Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J 2014; 35: 3033-69. Konstantinides SV Torbicki A Agnelli G Danchin N Fitzmaurice D Galiè N Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism Eur Heart J 2014 35 3033 69
2 Borloz MP, Frohna WJ, Phillips CA, Antonis MS. Emergency department focused bedside
–6 months after evaluating the initial tumor response. The cause of death was determined as lung cancer when patients had local recurrence or metastases and no other causes of death except for cancer, were presented. Toxicities were evaluated using the Radiation Therapy Oncology Group and European Organization for Research and Treatment of Cancer criteria. 19 The following dosimetric factors were examined with the use of a dose volume histogram of the lung minus the GTV and heart: mean lung dose, lung V5 (lung irradiated 5 Gy [RBE]), lung V10, lung V15, lung V20, and
Tadej Dovšak, Alojz Ihan, Vojislav Didanovič, Andrej Kansky and Nataša Hren
Black RJ, Bray F, Ferlay J, Parkin DM. Cancer incidence and mortality in the EuropeanUnion: cancer registry data and estimates of national incidence for 1990. Eur J Cancer 1997; 33: 1075-107.
Forastiere A, Koch W, Trotti A, Sidransky D. Head and Neck Cancer. N Engl J Med 2001; 345: 1890-900.
Rogers SN, Brown JS, Woolgar JA, Lowe D, Magennis P, Shaw RJ, et al. Survival following primary surgery for oral cancer. Oral Oncol 2009; 45: 201
Lei Du, Xin Xin Zhang, Lin Chun Feng, Jing Chen, Jun Yang, Hai Xia Liu, Shou Ping Xu, Chuan Bin Xie and Lin Ma
2014-048-01, and all eligible patients provided informed consent in written form.
Inclusion criteria were as follows: histologically proven type I and II NPC according to World Health Organization (WHO) criteria; stage I–IVa according to the Union for International Cancer Control (UICC) 2002 Staging System; aged between 15 and 75 years; Karnofsky performance status score ≥ 70; white blood cell count ≥ 3,500/μL, platelet count ≥ 100,000/μL, serum creatinine concentration < 133 umol/L, and liver transaminase level < 2.0 times of the upper normal value. Exclusion
Irena Oblak, Monika Cesnjevar, Mitja Anzic, Jasna But Hadzic, Ajra Secerov Ermenc, Franc Anderluh, Vaneja Velenik, Ana Jeromen and Peter Korosec
the Union for International Cancer Control (UICC). 20
Pre-treatment evaluation consisted of physical and digital rectal examination, rectoscopy with biopsy and fine needle aspiration biopsy of enlarged inguinal lymph nodes, also ultrasound-guided, like in other cancer patients. 21 Imaging included chest X-ray or computer tomography (CT) of chest, abdominal ultrasound (US) or CT and magnetic resonance imaging (MRI) of the pelvis. Laboratory tests included serum chemistry and complete blood count in all patients, and testing for HIV
Tomaz Jagric, Bojan Ilijevec, Vaneja Velenik, Janja Ocvirk and Stojan Potrc
conducted in Japan, proved beyond any doubt that adjuvant treatment can improve survival even in patients after adequate lymphadenectomy. 6 But the results from FLAGS trial showed that the tolerance of S1 agent in Caucasian population was poor, and only a fraction of patients with esophago-gastric junction were included. 2 Meanwhile, in Europe the results of the MAGIC trial proved the efficiency of perioperative chemotherapy. 3 Nonetheless, a sufficient lymph node dissection was performed only in 40% of patients and only 40% of patients could successfully end all
Mirjam Cvelbar, Marko Hocevar, Srdjan Novakovic, Vida Stegel, Andraz Perhavec and Mateja Krajc
EOC aged 45 to 49 years at the time of diagnoses who were diagnosed in the period 1999–2010.
All germinal BRCA1/2 mutation (gBRCA1/2m) positive patients were offered inclusion into the screening and prophylactic program for the highrisk group for breast cancer. In addition, since in the meantime the first PARP inhibitor was registered in EuropeanUnion for therapy of BRCA positive serous ovarian cancers, in case of relapses mutation carriers were offered this treatment. Following new guidelines of SGO and National Comprehensive Cancer Network (NCCN), genetic
Igor Stojkovski, Valentina Krstevska and Snezhana Smichkoska
in definition of gross tumor volume (GTV) in patients with glioblastoma. In studies conducted by EORTC (European Organization for Research and Treatment of Cancer) only one contoured gross tumor volume is used which is defined as an enhanced visible tumor on MR images prior the surgery expanded respectively to clinical target volume (CTV) and planning target volume (PTV) according ESTRO-ACROP Guidelines. 7
In contrast in studies conducted by RTOG (Radiation Therapy Oncology Group) definition of volumes in according to “cone-down” approach, which means that there
Alenka Franko, Nika Kotnik, Katja Goricar, Viljem Kovac, Metoda Dodic-Fikfak and Vita Dolzan
asbestos cement manufacturing plant of Salonit Anhovo, Slovenia, but did not develop any disease associated with asbestos exposure. All patients and controls were from Central European Caucasian (Slovenian) population. The study was approved by the Slovenian Ethics Committee for Research in Medicine and was carried out according to the Helsinki Declaration. The subjects were included in the study after providing a written informed consent.
The diagnosis of MM was made by means of thoracoscopy or video-assisted thoracoscopic surgery (VATS) in patients with
Urska Ivanus, Tine Jerman, Alenka Repse Fokter, Iztok Takac, Veronika Kloboves Prevodnik, Mateja Marcec, Ursula Salobir Gajsek, Maja Pakiz, Jakob Koren, Simona Hutter Celik, Kristina Gornik Kramberger, Ulrika Klopcic, Rajko Kavalar, Simona Sramek Zatler, Biljana Grcar Kuzmanov, Mojca Florjancic, Natasa Nolde, Srdjan Novakovic, Mario Poljak and Maja Primic Zakelj
regular cervical cancer screening programme by offering self-sampling kits: a systematic review and meta-analysis of randomised trials Eur J Cancer 2015 51 2375 85 10.1016/j.ejca.2015.07.006
12 Von Karsa L, Arbyn A, De Vuyst H, Dillner J, Dillner L, Franceschi S, et al. (2015). Executive summary. In: European guidelines for quality assurance in cervical cancer screening. Second edition, Supplements. Anttila A, Arbyn A, De Vuyst H, Dillner J, Dillner L, Franceschi S, et al, editors. Luxembourg: Office for Official Publications of the EuropeanUnion. p. XIII