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Liquid chromatographic enantioseparation of thalidomide and its derivatives on cyclodextrin-bonded stationary phases

Irodalomjegyzék 1. Eriksson T, Bjorkman S, Hoglund P. Clinical pharmacology of thalidomide. Eur J Clin Pharmacol. 2001; 57(5):365-376. 2. Melchert M, List A. The thalidomide saga. Int J Biochem Cell Biol. 2007; 39(7-8):1489-1499. 3. Ridings JE. The thalidomide disaster, lessons from the past. Methods Mol Biol. 2013; 947:575-586. 4. Eriksson T, Bjorkman S, Roth B, Hoglund P. Intravenous formulations of the enantiomers of thalidomide: pharmacokinetic and initial pharmacodynamic characterization in man. J Pharm Pharmacol. 2000; 52

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8-Prenylnaringenin from hop (Humulus lupulus L.) – a panacea for menopause?

. Rad M, Hümpel M, Schaefer O, Schoemaker RC, Schleuning WD, Cohen AF et al. Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women. Br J Clin Pharmacol 2006; 62(3):288-296. 29. Nilsson S, Kela SM, Treuter E, Tujague M, Thomsen J, Andersson GR et al. Mechanisms of estrogen action. Physiological Reviews 2001; 81(4):1535-1565. 30. van Breemen RB, Yuan Y, Banuvar S, Shulman LP, Qiu X, Alvarenga RF et al. Pharmacokinetics of prenylated hop phenols in women

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Indirect relationship between lipophilicity and maximum residue limit of drugs determined for fatty tissue

References 1. Balaz S., Lukacova V.: Subcellular pharmacokinetics and its potential for library focusing. J Mol Graph Model 2002, 20, 479–490. 2. Blackwell T.: Veterinary Medical Ethics: Ethical question of the month - July 2002. Can Vet J 2002, 43, 749–750. 3. Bolton S., Bon C.: Pharmaceutical Statistics: Practical and Clinical Applications, Fourth Edition, Revised and Expanded, Informa Health Care, New York, 2003. 4. Bonora E., Willeit J., Kiechl, S., Oberhollenzer F., Egger G., Bonadonna R., Muggeo M.: Relationship between insulin and

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Analysis of scopoletin and mangiferin in botanicals and formulations of Shankhpushpi by HPLC

. The determination of scopoletin in environmental tobacco smoke by high-performance liquid chromatography. J Liq Chromatogr 1994; 17(12): 2723-2736. doi: 18. Suryawanshi S, Asthana RK, Gupta RC. Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation. J Chromatogr B: Anal Technol Biomed Life Sci 2007; 858: 211–219. doi:

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Comparison of laparoscopic and traditional abomasal cannulation in sheep

parameters during NOTES compared with laparoscopy in a randomized blinded porcine trial. Surg Endosc 2009, 23, 178-181. 4. Cambridge A.J., Tobias K.M., Newberry R.C., Sarkar D.K.: Subjective and objective measurements of postoperative pain in cats. J Am Vet Med Assoc 2000, 217, 685-690. 5. Charles B.G., Filippich L., Pass M.A.: Pharmacokinetics and absolute bioavailability of cyclosporine following intravenous and abomasal administration to sheep. J Pharm Pharmacol 1993, 45, 821-824. 6. Choileain N.N., Redmond P.: Cell

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Resveratrol improves the lipid profile promoted by red yeast rice (monacolin k) in patients with moderate dyslipidemia: An open-label, randomized, parallel-group controlled clinical trial

, Williams T, Luo H, Ke H, Rehmann H, Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V, Chung JH. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting Camp phosphodiesterases. Cell. 2012; 3;148:421-33. 6. Das S, Lin HS, Ho PC, Ng KY. The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol. Pharm Res. 2008; 25:2593-600. 7. Subramanian L, Youssef S, Bhattacharya S, Kenealey J, Polans AS, van Ginkel PR. Resveratrol: challenges in translation to the clinic-- a critical

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Synthesis and analgesic activities of some new 5-chloro-2(3H)-benzoxazolone derivatives

pharmacokinetic-pharmacodynamic model of tolerance to morphine analgesia during infusion in rats. J Pharmacokinet Biopharm 1995; 23: 531-549.

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Experimental gentamicin-induced nephrotoxicity in the sheep

-156. 7. Fadel A.A., Larking H.A.: Gentamicin-induced nephrotoxicosis in lambs. Res Vet Sci 1996, 61, 187-192. 8. Frazier D.L., Aucoin D.P., Riviere J.E.: Gentamicin pharmacokinetics and nephrotoxicity in naturally acquired and experimentally induced disease in dogs. J Am Vet Med Assoc 1988, 192, 57-63. 9. Fukuda Y., Malmborg A.S., Aperia A.: Gentamicin inhibition of Na+, K+ ATPase in rat kidney cells. Acta Physiol Scand 1991, 141, 27-34. 10. Garry F., Chew D.J., Hoffsis G.F.: Enzymuria as an index of renal damage in sheep

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Advances in antibiotic therapy for infection after the surgical installation of implants to treat internal fractures

therapy for chronic osteomyelitis in adults. Clin Infect Dis, 2012, 54(3): 393-407. 6 Conterno LO, Turchi MD. Antibiotics for treating chronic osteomyelitis in adults. Cochrane Database Syst Rev, 2013, 9(19): 1292. 7 Tone A, Nguyen S, Devemy F, et al . Six-week versus twelve – week antibiotic therapy for nonsurgically treated diabetic foot osteomyelitis: a multicenter open-label controlled randomized study. Diabetes Care, 2015, 38(2): 302-307. 8 Landersdorfer CB, Bulitta JB, Kinzig M, et al . Penetration of antibacterials into bone pharmacokinetic

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P-R interval in porcine model of chronic tachycardia-induced cardiomyopathy

atypical atrioventricular Wenckelbach periodicity. J Electrocardiol 1989, 22 , 227-233. 12. Koike Y., Shimamura K., Shudo I., Saito H.: Pharmacokinetics of verapamil in man. Res Commun Chem Pathol Pharmacol 1979, 24, 37-47. 13. Laitinen T., Lyyra-Laitinen T., Huopio H., Vauhkonen I., Halonen T., Hartikainen J., Niskanen L., Laakso M.: Electrocardiographic alterations during hyperinsulinemic hypoglycemia in healthy subjects. Ann Noninvasive Electrocardiol 2008, 13, 97-105. 14. Levy M.N., Zieske H.: Autonomic control of

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