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Nevena Gajovic, Ivan Jovanovic, Aleksandar Ilic, Nevena Jeremic, Vladimir Jakovljevic, Nebojsa Arsenijevic and Miodrag L. Lukic

, Priatel JJ, Tan R. (2011). Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling. Diabetes. 60(3), 857-66. 12. Slauenwhite D, Johnston B. (2015). Regulation of NKT cell localization in homeostasis and infection. Frontiers in Immunology 6:255. doi: 10.3389/fimmu.2015.00255. 13. Kumar V, Delovitch TL. (2014). Different subsets of natural killer T cells may vary in their roles in health and disease. Immunology. 142(3), 321-36. 14. Coquet JM, Kyparissoudis K, Pellicci DG

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T. Maślanka and J.J. Jaroszewski

References Blache C, Adriouch S, Calbo S, Drouot L, Dulauroy S, Arnoult C, Le Corre S, Six A, Seman M, Boyer O ( 2009 ) Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells. J Immunol 183: 4182- -4186. Chen X, Oppenheim JJ, Winkler-Pickett RT, Ortaldo JR, Howard OM ( 2006 ) Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3+CD4+CD25+ T regulatory cells in vivo and enhances their capacity to suppress EAE. Eur J Immunol 36: 2139-2149. Maeda Y, Tanaka R

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Bojana Stojanović, Jelena Milovanović, Aleksandar Arsenijević, Marija Milovanovic and Miodrag L. Lukic

induction of active EAE but not to EAE mediated by the intact T lymphocyte line. Eur J Immunol. 1981; 11(11): 949-952. 9. Costantino CM, Baecher-Allan C, Hafler DA. Multiple sclerosis and regulatory T cells. J Clin Immunol. 2008; 28(6): 697-706. 10. O’Connor RA, Anderton SM. Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease. J Neuroimmunol. 2008; 193(1-2): 1-11. 11. Zhang X, Koldzic DN, Izikson L, et al. IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD

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Ting Miao

References 1 Koichi Yanaba, Jean-David Bouaziz, et al . A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immun, 2008, 28(5):639-50. 2 Mizoguchi A, Bhan AK. A case for regulator y B cells. J Immun, 2006,176(2):705-10. 3 Yang M, Rui K, Wang SG, et al . Regulatory B cells in autoimmune diseases. Cell Mol Immun, 2013, 10(13):122-32 4 Wolf SD, Dittel BN, Hardardottir F, et al . Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med

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Paweł Wojtaszczyk, Krzysztof Kostro, Krzysztof Niemczuk, Urszula Lisiecka, Krzysztof Stojecki and Andrzej Żmuda

References 1. Bernhagen J., Calandra T., Bucala R.: Regulation of the immune response by macrophage migration inhibitory factor: biological and structural features. J Mol Med 1998, 76, 151-161. 2. Bevan M.J.: Helping the CD8+ T-cell response. Nat Rev Immunol 2004, 4, 595-602. 3. Biller B.J., Elmslie R.E., Burnett R.C., Avery A.C., Dow S.W.: Use of Foxp3 expression to identify regulatory T cells in healthy dogs and dogs with cancer. Vet Immunol Immunopathol 2007, 116, 69-78. 4. Carlsson P

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Zlate Stojanoski, Anzelika Karadzova-Stojanoska, Aleksandra Pivkova-Veljanovska, Sonja Genadieva-Stavrik, Lazar Cadievski, Martin Ivanovski, Oliver Karanfilski, Lidija Cevreska and Borce Georgievski

References 1. Tyndall A, and Gratwohl A. Blood and marrow stem cell transplants in auto-immune disease: a consensus report written on behalf of the European League against Rheumatism (EULAR) and the European Group for Blood and marrow transplantation (EBMT). Bone Marrow Transplantation 1997; 19: 643-645. 2. van Laar JM, Farge D, Sont JK, et al . EBMT/EULAR Scleroderma Study Group.: Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial. JAMA

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Lamija Zecevic, Jasenko Karamehic, Jozo Coric, David Stubljar, Nesina Avdagic, Kenan Selmanovic, Tomislav Jukic and Sinisa Savic

Activity Index SLICC, Systemic Lupus International Collaborating Clinics SPE, specificity TCR, T-cell receptor Treg, T regulatory cells References 1. D’Cruz DP, Khamashta MA, Hughes GR. Systemic lupus erythematosus. Lancet 2007; 369 (9561): 587–96. 2. Choi J, Kim ST, Craft J. The pathogenesis of systemic lupus erythematosus: an update. Curr Opin Immunol 2012; 24: 651–7. 3. Castro C, Gourley M. Diagnostic testing and interpretation of tests for autoimmunity. J Allergy Clin Immunol 2010; 125: 238–47. 4. Tomioka R, Tani K, Sato K

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Nattiya Hirankarn, Krongkamol Hemwijit, Thitima Benjachat and Yingyos Avihingsanon

References 1. Tsao BP. Update on human systemic lupus erythematosus genetics. Curr Opin Rheumatol. 2004; 16:513-21. 2. Zhang H, Yang P, Zhou H, Meng Q, Huang X: Involvement of Foxp3-expressing CD4+ CD25+ regulatory T cells in the development of tolerance induced by transforming growth factor-beta2-treated antigen-presenting cells. Immunology. 2008; 124: 304-14. 3. Namba K, Kitaichi N, Nishida T, Taylor AW. Induction of regulatory T cells by the immunomodulating cytokines alpha-melanocyte-stimulating hormone and

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Sebastian Radej, Jacek Roliński, Karol Rawicz-Pruszyński, Paweł Bury, Grzegorz Borowski, Jacek Furmaga, Andrzej Chrościcki, Grzegorz Wallner and Ryszard Maciejewski

References 1. Scurr M, Ladell K, Besneux M et al.: Highly prevalent colorectal cancer-infiltrating LAPţFoxp3- T cells exhibit more potent immunosuppressive activity than Foxp3ţ regulatory T cells. MucosalImmunology 2014; 7(2): 428-39. 2. Madhav D. Sharma, De-Yan Hou, Yanjun Liu et al.: Indoleamine 2,3-dioxygenase controls conversion of Foxp3_ Tregs to TH17-like cells in tumordraining lymph nodes. Blood 2009; 113(24): 6102-11. 3. Liufu Deng, Haizeng Zhang, Yan Luan et al.: Accumulation of Foxp3+ T Regulatory

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Pei-yan Zhang, Si-min Yao, Fan Zhang, Ming-xia Zhang, Wei Li, Jing Yuan, Xin-chun Chen and Bo-ping Zhou

, Pitzalisd C, Lord GM, Kirkham BW, et al. In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. Proc Nati Acad Sci USA 2009;106:6232-6237. 4 O’Quinn DB, Palmer MT, Lee YK, Weaver CT. Emergence of the Th17 pathway and its role in host defense. Adv Immunol 2008;99:115-163. 5 Nan XP, Zhang Y, Yu HT, Li Y, Sun RL, Wang JP, et al. Circulating CD4+CD25high regulatory T cells and expression of PD-1 and BTLA on CD4+ T cells in patients with chronic hepatitis B virus infection. Viral Immunol 2010