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MR-proADM and MR-proANP levels in patients with acute pulmonary embolism

Introduction Classification of the Pulmonary embolism (PE) patients for early mortality as a high-risk, intermediate-risk or low-risk determines the treatment options and prognosis ( 1 ). Clinical parameters [Pulmonary Embolism Severity Index (PESI), simplified PESI score (sPESI)], right ventricular dysfunction (RVD) markers, thrombotic load markers and myocardial damage markers in hemodynamically stable acute symptomatic PE cases are the most commonly used prognostic factors. In the determination of the risk of early poor prognosis in normotensive PE cases

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The genes regulating maintenance of cellular protein location are differentially expressed in porcine epithelial oviductal cells during longterm in vitro cultivation

the relation between the genes belonging to the chosen GO terms using the GOplot package [ 5 ]. The GoPlot package had calculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of the count. This information allowed to estimate the change course of each gene-ontology term. Interactions between differentially expressed genes/proteins belonging to the studied gene ontology groups were investigated by the STRING10 software (Search Tool for the Retrieval of Interacting Genes) [ 6 ]. The list of gene

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Analysis of expression of genes responsible for regulation of cellular proliferation and migration – microarray approach based on porcine oocyte model

, Visualization and Integrated Discovery) [ 13 ], where genes belonging to the terms of all four Gene Ontologies (GOs) of interest were extracted. Expression data of these genes was also subjected to a hierarchical clusterization procedure, with their expression values presented as a heat map. Subsequently, we analyzed the relation between the genes belonging to the chosen GO terms using theGOplot package [ 14 ]. The GoPlot package had calculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of the count

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Genes encoding proteins regulating fatty acid metabolism and cellular response to lipids are differentially expressed in porcine luminal epithelium during long-term culture

Annotation, Visualization and Integrated Discovery) [ 7 ], where genes belonging to the terms of all four Gene Ontologies (GOs) of interest were extracted. Expression data of these genes was also subjected to a hierarchical clusterization procedure, with their expression values presented as a heat map. Subsequently, we analyzed the relation between the genes belonging to the chosen GO terms using theGOplot package [ 8 ]. The GoPlot package had calculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of

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Genes regulating biochemical pathways of oxygen metabolism in porcine oviductal epithelial cells during long-term IVC

, with their expression values presented as a heatmap. Subsequently, we analyzed the relation between the genes belonging to chosen GO terms with the GOplot package [ 21 ]. The GoPlot packagecalculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of the count. This information allowed to estimate the change course of each gene-ontology term. Interactions between differentially expressed genes/proteins belonging to the studied gene ontology group were investigated using the STRING10 software

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Biochemical properties of cofactor and coenzyme metabolism in porcine oviductal epithelial cells – a microarray study

analyzed the relation between the genes belonging to chosen GO terms with the GOplot package [ 13 ]. The GoPlot package calculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of the count. This information allowed to estimate the change course of each gene-ontology term. Interactions between differentially expressed genes/proteins belonging to the studied gene ontology group were investigated using the STRING10 software (Search Tool for the Retrieval of Interacting Genes) [ 14 ]. The list of the

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Pentoxifylline with metformin treatment improves biochemical parameters in patients with nonalcoholic steatohepatitis

, many biochemical parameters, for instance, liver enzymes, platelets, albumin, and scoring systems based on aforementioned markers, have been used to investigate NAFLD ( 14 , 15 , 16 ). Pentoxifylline (PTX), a phosphodiesterase inhibitor, although commonly used for peripheral vascular disease, is one of the antioxidants considered for NASH treatment. Besides its antioxidant activity and inhibition of proinflammatory cytokine production (tumor necrosis factor alpha – TNF-α), it exerts pleiotropic pharmacological effects ( 17 ). Additionally, it has been implied

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‘Cell cycle’ and ‘cell death’- related genes are differentially expressed during long – term in vitro real-time cultivation of porcine oviductal epithelial cells

, we analyzed the relation between the genes belonging to chosen GO terms with theGO-plot package [ 7 ]. The GoPlot package calculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of the count. This information allowed estimating the change course of each gene-ontology term. Interactions between differentially expressed genes/proteins belonging to the studied gene ontology group were investigated using the STRING10 software (Search Tool for the Retrieval of Interacting Genes) [ 8 ]. The list of

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Differential expression pattern of genes involved in oxygen metabolism in epithelial oviductal cells during primary in vitro culture

of these genes was also subjected to a hierarchical clusterization procedure, with their expression values presented as a heat map. Subsequently, we analyzed the relation between the genes belonging to the chosen GO terms using the GO plot package [ 7 ]. The Go plot package had calculated the z-score: the number of up- regulated genes minus the number of down- regulated genes divided by the square root of the count. This information allowed to estimate the change course of each gene-ontology term. Interactions between differentially expressed genes

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The impact of obesity to antioxidant defense parameters in adolescents with increased cardiovascular risk

, Božić-Antić I, Vekić J, Bjekić-Macut J, Kastratović-Kotlica B, Andrić Z, Ilić D. Evaluation of a summary score for dyslipidemia, oxidative stress and inflammation (the doi score) in women with polycystic ovary syndrome and its relationship with obesity. J Med Biochem 2018; 37: 476–85. 10.2478/jomb-2018-0008 30584408 Perović Blagojević I Ignjatović S Macut Dj Kotur-Stevuljević J Božić-Antić I Vekić J Bjekić-Macut J Kastratović-Kotlica B Andrić Z Ilić D Evaluation of a summary score for dyslipidemia, oxidative stress and

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