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Genetic Parameters for Clinical Mastitis, Fertility and Somatic Cell Score in Czech Holstein Cattle

References Alam M., Cho C.I., Choi T.J., Park B., Choi J.G., Choy Y.H., Lee S.S., Cho K.H. (2015). Estimation of genetic parameters for somatic cell scores of Holsteins using multi-trait lactation models in Korea. Asian Australas. J. Anim. Sci., 28: 303–310. Ali A.K.A., Shook G.E. (1980). An optimum transformation for somatic cell concentration in milk. J. Dairy Sci., 63: 487–490. Buch L.H., Sorensen M.K., Lassen J., Berg P., Jakobsen J.H., Johansson K., Sorensen A.C. (2011). Udder health and female fertility traits are favourably correlated and

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Serum ghrelin level is associated with cardiovascular risk score


Ghrelin, a newly discovered bioactive peptide, was originally reported to induce growth hormone release. Recent studies have shown beneficial hemodynamic effects of ghrelin in the cardiovascular system to support the wide distribution of its receptors in cardiovascular tissues. The aim of the study was to determine whether cardiovascular risk factors influence plasma ghrelin levels.

Methods. We evaluated in the Rehabilitation Hospital Cluj-Napoca, Cardiology - Department 88 consecutive subjects, 65 (73.86%) being women, with mean age 61.7±10.33 years. We assessed the presence of cardiovascular risk factors (obesity, arterial hypertension, diabetes mellitus, metabolic syndrome, smoking and lipid fractions). Plasma ghrelin levels were determined with a commercial ELISA kit (pg/ml).

Results. After the evaluation of cardiovascular risk factors, we found no statistically significant difference between ghrelin levels in the patients with vs those without cardiovascular risk factors (p>0.05). A negative correlation was found between ghrelin levels and age, r = −0.32 (p <0.05). Using the HeartScore Internet tool we calculated the cardiovascular risk for each patient according to the risk score system (SCORE) for high cardiovascular risk countries. Statistically, the risk of fatal cardiovascular events in the next 10 years was indirectly correlated with the ghrelin levels in each patient - correlation between ghrelin levels and SCORE system r=−0.25, p=0.015. In conclusion, low serum ghrelin concentrations are associated with an increased global cardiovascular risk, calculated based on the European SCORE scale. However, we could not demonstrate a direct relationship between any of the major risk factors and ghrelin.

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The Effect of Body Condition Score on the Biochemical Blood Indices and Reproductive Performance of Dairy Cows

References Akbar H., Grala T.M., Vailati Riboni M., Cardoso F.C., Verkerk G., Mc Gowa n J., Macdonald K., Webster J., Schutz K., Meier S., Matthews L., Roche J.R., Loor J.J. (2015). Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows. J. Dairy Sci., 98: 1019-1032. Busato A., Faissle D., Kupfer U., Blum J.W. (2002). Body condition scores in dairy cows: associations with metabolic and endocrine changes in healthy dairy cows. J. Vet

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Relationship between the pre- and postpartum body condition scores and periparturient indices and fertility in high-yielding dairy cows

References 1. Adamski M.: Kondycja krów w okresie okołoporodowym a poziom wybranych parametrów krwi i płodności. Publication of the Wrocław University of Environmental and Life Sciences, Wrocław, 2010, pp. 7-84. 2. Akbar H., Grala T.M., Vailati Riboni M., Cardoso F.C., Verkerk G., McGowan J., Macdonald K., Webster J., Schutz K., Meier S., Matthews L., Roche J.R., Loor J.J.: Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows. J

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Application of independent component analysis for speech–music separation using an efficient score function estimation

Source Separation by Adaptive Estimation of Score Function Difference, Proceedings of ICA 2004, Granada, Spain, 2004, pp. 9-17. [15] VLASSIS, N.-MOTOMURA, Y. : Efficient Source Adaptivity in Independent Component Analysis, IEEE Transaction on Neural Networks 12 No. 3 (2001), 559-566. [16] BABAIE-ZADE, M.-JUTTEN, C. : A General Approach for Mutual Information Minimization and its Application to Blind Source Separation, Signal Processing 85 No. 5 (2005), 975-995. [17] AMARI, S.-CICHOCKI, A.-YANG, H. H. : A New Learning

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Predictive Value of Updating te Score Cardiovascular Risk Assessment Engine with Novel Biomarkers in a Type 2 Diabetes Population

, Simmons RK, Sharp SJ, Griffin SJ, Wareham NJ. Cardiovascular risk assessment scores for people with diabetes: a systematic review. Diabetologia 52: 2001-2014, 2009. 9. Pearson TA, Mensah GA, Alexander RW et al. Markers of inflammation and cardiovascular disease: application to clinical public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107: 499-511, 2003. 10. Sinderman AJ, Williams K, Contois JH et al. A metaanalysis of low

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Net promoter score, growth, and profitability of transportation companies

1 Introduction Strategies of many contemporary companies are almost entirely focused on consumers. These companies, with the use of, inter alia, surveys or focus groups, constantly put their consumers under a microscope, aiming to understand their behavior. This is, however, not a straightforward task. Typically, companies tend to look at satisfaction measures, market shares, or sales figures. According to research undertaken by Bain Company, there exists a certain body of consumers, who, despite providing scores indicating “satisfied” in surveys, soon move

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Impact of perioperative treatment on survival of resectable gastric cancer patients after D2 lymphadenectomy: a single European centre propensity score matching analysis

) chemotherapy. Therefore, we conducted an analysis with propensity score matched patients to determine the role of perioperative and adjuvant chemotherapy in patients after D2 lymphadenectomy. Patients and methods Patients Since 1991, 1563 patients were operated for gastric cancer in the department for Abdominal and General Surgery at the University Clinical Centre Maribor, Slovenia. The demographic characteristics of patients, the characteristics of the surgical procedures, and the pathological characteristics of tumours were prospectively stored on a computer

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Brief communication (Original). Pregnancy-associated plasma protein A (PAPP-A) and severity of coronary atherosclerosis assessed by angiographic Gensini score

GG. A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol. 1983; 51:606. 12. Oishi Y, Wakatsuki T, Nishikado A, Oki T, Ito S. Circulating adhesion molecules and severity of coronary atherosclerosis. Coron Artery Dis. 2000; 11: 77-81. 13. Qin QP, Wittfooth S, Pettersson K. Measurement and clinical significance of circulating PAPP-A in ACS patients. Clin Chim Acta. 2007; 380:59-67. 14. Lund J, Qin QP, Ilva T, Nikus K, Eskola M, Porela P, et al. Pregnancy-associated plasma

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Integrated ST Segment Elevation Scores and In-hospital Mortality in STEMI Patients Undergoing Primary PCI


The objective of this study was to study the integrated score of ST-segment resolution (ISSTE) and in-hospital death in patients undergoing primary percutaneous intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI).

Material and Methods: This prospective study included 586 consecutive patients admitted with STEMI to the Cardiology Clinic of the County Emergency Clinical Hospital of Tîrgu Mureș, between January 1st, 2013 and December 31, 2014, who underwent pPCI in less than twelve hours after the onset of symptoms. Clinical and demographic data were analyzed in 539 (91.9%) survivors (Group 1) and 47 (8.1%) nonsurvivors (Group 2). The Integrated Score of ST elevation (ISSTE) was calculated by summing the amplitude of the ST segment elevation in all the 12 leads, before and at 2 hours after revascularization.

Results: The ISSTE score calculated at baseline, immediately before the primary percutaneous coronary intervention, was significantly higher in Group 2 as compared to Group 1 (13.9 ± 1.2 vs. 11.0 ± 0.2, p = 0.026). At the same time, the ISSTE score calculated at 2 hours after the coronary intervention was significantly higher for patients in Group 2 (7.36 ± 1.12 vs. 2.9 ± 0.1, p <0.0001). Analysis of the dynamics of the ISSTE score indicated that patients who survived presented a more expressed reduction in the ISSTE score following pPCI, as compared to those who subsequently died (73.5% reduction in Group 1 compared to 47.2% reduction in Group 2, p <0.0001). In-hospital mortality was significantly higher in the group of patients with >50% reduction in the ISSTE score. The in-hospital death rate was 5.4% in patients with >50% reduction in the ISSTE score, compared to 19.4% for those who presented less than 50% reduction in the ISSTE score following pPCI (p <0.0001). The rate of successful reperfusion rate, expressed by the reduction in ISSTE score, was 83.8% in Group 1, compared to 55.3% in Group 2 (p <0.0001), indicating that the absence of an efficient reperfusion after pPCI is associated with a higher mortality in STEMI patients, and could be evaluated using regression of the ISSTE score, which proved to be directly associated with mortality.

Conclusion: The ISSTE score is shown to be an effective ECG-derived marker of myocardial damage in STEMI patients. A high ISSTE score is associated with higher mortality, while a reduction in the ISSTE score after pPCI may indicate an efficient reperfusion and a decrease in mortality in the first days after infarction.

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