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Gamma-enolase: a well-known tumour marker, with a less-known role in cancer

serum markers of neuronal damage following severe hypoglycaemia in adults with insulin-treated diabetes mellitus. Diabetes Metab Res Rev 1999; 15: 5-12. 109. Collazos J, Genolla J, Ruibal A. Neuron-specific enolase concentrations in serum in benign liver diseases. Clin Chem 1991; 37: 579-81. 110. Massabki PS, Silva NP, Lourenco DM, Andrade LE. Neuron specific enolase concentration is increased in serum and decreased in platelets of patients with active systemic sclerosis. J Rheumatol 2003; 30: 2606-12. 111. Petrak J, Ivanek R, Toman O

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Nuclear Transcription Factor Kappa B (NF-кB) and Molecular Damage Mechanisms in Acute Cardiovascular Diseases. A Review

Res. 2010;106:1035-1039. doi: 10.1161/CIRCRESAHA.110.218297. 64. Caporali A, Meloni M, Vo C, et al. Deregulation of microRNA-503 Contributes to Diabetes Mellitus-Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia. Circulation. 2011;123:282-291. doi: 10.1161/CIRCULATIONAHA.110.952325. 65. Liu C, Liu N, Cao B, et al. CircRNAs as Potential Biomarkers in Gastrointestinal Tract Tumors : Opportunities and Challenges. Clin Lab. 2018;64:141-145. doi: 10.7754/Clin.Lab.2017.170731. 66. Giden R, Gökdemir MT, Erel Ö, et

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Treatment-related cardiovascular toxicity in long-term survivors of testicular cancer

31 Stehouwer CD, Yudkin JS, Fioretto P, Nosadini R. How heterogeneous is microalbuminuria in diabetes mellitus? The case for „benign“ and „malignant“ microalbuminuria. Nephrol Dial Transplant 1998; 13 : 2751-4. 10.1093/ndt/13.11.2751 Stehouwer CD Yudkin JS Fioretto P Nosadini R How heterogeneous is microalbuminuria in diabetes mellitus? The case for „benign“ and „malignant“ microalbuminuria Nephrol Dial Transplant 1998 13 2751 4 32 Hillege HL, Fidler V, Diercks GF, van Gilst WH, de Zeeuw D, van Veldhuisen DJ, et al. Urinary albumin excretion predicts

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Expression of LOC285758, a potential long non-coding biomarker, is methylation-dependent and correlates with glioma malignancy grade

inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer Oncotarget 2016 7 44505 44521 10.18632/oncotarget.9887 48 Qu X, Yu H, Jia B, Yu X, Cui Q, Liu Z, et al., Association of downregulated HDAC 2 with the impaired mitochondrial function and cytokine secretion in the monocytes/macrophages from gestational diabetes mellitus patients. Cell Biol Int 2016; 40 : 642-51. 10.1002/cbin.10598 Qu X, Yu H, Jia B, Yu X, Cui Q, Liu Z, et al Association of downregulated HDAC 2 with the impaired

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Cerebral toxoplasmosis in a diffuse large B cell lymphoma patient

systemic diffuse large B cell lymphoma (DLBCL) presented to our oncology clinic in the beginning of September 2013 with high fever, headache and altered mental status. Her past medical history included arterial hypertension and type 2 diabetes mellitus, both well controlled with medications. Since 2010, she was treated for marginal zone B cell lymphoma stage IV A, involving the spleen, bone marrow and lymph nodes. A splenectomy was performed in July 2011. At that time, no other treatment was administered due to clinical remission. In August 2012, the disease progressed

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Optic nerve ultrasound for fluid status assessment in patients with severe preeclampsia

diabetes mellitus. None had prior ocular surgery or ocular trauma. Median maternal age was 31 years (range 21–44 years); median maternal pre-pregnancy body mass index was 23 kg/m 2 (range 19–32 kg/m 2 ), and median gestational age at study inclusion was 32 5/7 weeks (range 22 3/7–39 4/7 weeks). Twenty-three (77%) patients were nulliparous. Severe features of preeclampsia meeting the inclusion criteria were: hypertension in all 30 cases, headache in 14 (47%) cases, visual disturbances in four (13%) cases, elevated liver enzymes in 10 (33%) cases, thrombocytopenia in

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Is carotid stiffness a possible surrogate for stroke in long-term survivors of childhood cancer after neck radiotherapy?

in controls and cancer survivors Charasteristics and risk factors Controls Survivors P value Total 26 23 Sex (male (%)) 6 (77) 7 (70) 0.40 Smoking (%) 8 (30.8) 7 (30.4) 0.613 Family history (%) 5 (20) 0 0.031 Arterial hypertension (%) 4 (15.4) 6 (26.1) 0.354 Diabetes mellitus 0 0 Age (years) 42.65 ± 5.38 40.22 ± 6.56 0.16 Total cholesterol (mmol/l) 5.7 ± 1.00 5.6 ± 1,01 0.646 Body mass index 25.4 ± 2.98 24.9 ± 1.85 0

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Voluntary deep inspiration breath-hold reduces the heart dose without compromising the target volume coverage during radiotherapy for left-sided breast cancer

. Patients with cardiac V25Gy ≥ 5% on FB treatment plan were offered V-DIBH. In addition, selected cases with lower V25Gy were entered on the V-DIBH protocol. This selection was performed at discretion of the treating radiation oncologist by considering patient-related factors such as age, pre-existent ischemic cardiac events and other co-morbidities, application of cardio-toxic medications, history of smoking, diabetes mellitus, hyperlipidemia and arterial hypertension. Our V-DIBH approach was adapted from the technique used in the UK HeartSpare study and was based on

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Perioperative increase in neutrophil CD64 expression is an indicator for intra-abdominal infection after colorectal cancer surgery

-test (mean, standard deviation) 1 Gender male 131 (65.5%) 86 (65.2%) 45 (66.2%) 1 Chi-square test 1 female 69 (34.5%) 46 (34.8%) 23 (33.8%) ASAscore I 14 (7%) 12 (9.1%) 2 (2.9%) 0.0503 Fisher’s exact test 0.8546 II 105 (52.5%) 74 (56.1%) 31 (45.6%) III 76 (38%) 42 (31.8%) 34 (50%) IV 5 (2.5%) 4 (3%) 1 (1.5%) Diabetes mellitus no 161 (80.5%) 110 (83.3%) 51 (75%) 0.2222 Chi-square test 1 yes 39 (19.5%) 22 (16.7%) 17 (25%) BMI

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