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Superoxide dismutase 1 and 2 gene polymorphism in Turkish vitiligo patients

puzzle: The pieces fall in place Pigment Cell Res. 2007 20 5 345 359 5 Ben Ahmed M, Zaraa I, Rekik R, Elbeldi-Ferchiou A, Kourda N, Belhadj Hmida N, et al . Functional defects of peripheral regulatory T lymphocytes in patients with progressive vitiligo. Pigment Cell Melanoma Res. 2011; 25(1): 99-109. 21985183 Ben Ahmed M Zaraa I Rekik R Elbeldi-Ferchiou A Kourda N Belhadj Hmida N Functional defects of peripheral regulatory T lymphocytes in patients with progressive vitiligo Pigment Cell Melanoma Res. 2011 25 1 99 109 6 Ongenae K, Geel NV, Naeyaert JM. Evidence for

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Analysis of the PPARD gene expression level changes in football players in response to the training cycle

]. Collection of Biological Material . Blood samples were collected before (T 1 ) and 12 hours after training (T 2 ). Before blood collection, the players had been resting in the supine position for 10 min. Blood was aspirated into 5 mL EDTA-containing tubes. For lymphocyte isolation, a density gradient cell separation solution Histopaque®-1077 (Sigma-Aldrich Co., St. Louis, MO, USA) was used. Blood needed for determination of lipid profiles was collected into the serum separator tubes. Gene Expression Analyses . RNA isolation was performed using the mirVana™ miRNA

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Hyperinsulinism-hyperammonemia syndrome in an infant with seizures

Brennan MF Cahill Jr GF Blood cell and plasma amino acid levels across forearm muscle during a protein meal Diabetes 1973 22 10 768 – 775 21 Flanagan SE, Patch AM, Locke JM, Akcay T, Simsek E, Alaei M, et al . Genome-wide homozygosity analysis reveals HADH mutations as a common cause of diazoxide-responsive hyperinsulinemic-hypoglycemia in consanguineous pedigrees. J Clin Endocrinol Metab. 2011; 96(3): 498-502. 10.1210/jc.2010-1906 Flanagan SE Patch AM Locke JM Akcay T Simsek E Alaei M Genome-wide homozygosity analysis reveals HADH

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The role of RNA metabolism in neurological diseases

21 Bartel DP. MicroRNAs: Target recognition and regulatory functions. Cell. 2009; 136(2): 215-233. Bartel DP MicroRNAs: Target recognition and regulatory functions. Cell 2009 136 2 215 233 22 Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by micro-RNAs: Are the answers in sight? Nat Rev Genet. 2008; 9(2): 102-114. 10.1038/nrg2290 Filipowicz W Bhattacharyya SN Sonenberg N Mechanisms of post-transcriptional regulation by micro-RNAs: Are the answers in sight? Nat Rev Genet 2008 9 2 102 114 23 Vasudevan S, Tong Y

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Effects of Taurine Against Histomorphological and Ultrastructural Changes in the Testes of Mice Exposed to Aluminium Chloride

agents in cAMP production and in steroidogenic response of isolated rat Leydig cells. Biol Cell 1984;52:259-66. PMID: 6273135 47. Dobashi M, Fujisawa M, Yamazaki T, Okuda Y, Kanzaki M, Tatsumi N, Tsuji T, Okada H, Kamidono S. Inhibition of steroidogenesis in Leydig cells by exogenous nitric oxide occurs independently of steroidogenic acute regulatory protein (star) mRNA. Arch Androl 2001;47:203-9. PMID: 11695844 48. Kostić TS, Andrić SA, Marić D, Kovačević RZ. Inhibitory effects of stress-activated nitric oxide on antioxidant enzymes and

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Investigation of circulating serum microRNA-328-3p and microRNA-3135a expression as promising novel biomarkers for autism spectrum disorder

Casallo G Gene and miRNA expression profiles in autism spectrum disorders Brain Res 2011 1380 85 97 13 Sarachana T, Zhou R, Chen G, Manji HK, Hu VW. Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med. 2010; 2(4): 23. 10.1186/gm144 Sarachana T Zhou R Chen G Manji HK Hu VW Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of

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Association of the MMP7 –181A>G promoter polymorphism with early onset of chronic obstructive pulmonary disease

-ligand, pro-tumor necrosis factor (TNF), and E-cadherin [ 10 , 11 ]. The production of the enzyme is highly up-regulated by injury or exposure to bacteria, stimulating cell migration and coordinating the inflammatory response [ 12 , 13 , 14 ]. Thus, MMP-7 participates in the processes of defense, repair and inflammation. In the promoter of the gene of MMP-7 an A>G transition has been identified as a functional polymorphism ( MMP7 –181A>G; rs11568818). The polymorphism has been shown to modulate transcriptional activity by influencing the binding of nuclear regulatory

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Complement Factor H Y403H Polymorphism in the Turkish Population

common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to agerelated macular degeneration. Proc Natl Acad Sci USA. 2005; 102(20): 7227-7232. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA. Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005; 308(5720): 419-421. Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS

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Glutathionylation: a regulatory role of glutathione in physiological processes

References 1. Josephy PD. Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. Hum Genomics Proteomics 2010;2010:876940. doi: 10.4061/2010/876940 2. Wu D, Meydani SN, Sastre J, Hayek M, Meydani M. In vitro glutathione supplementation enhances interleukin-2 production and mitogenic response of peripheral blood mononuclear cells from young and old subjects. J Nutr 1994;124:655-63. PMID: 8169657 3. Espinosa-Diez C, Miguel V, Mennerich D, Kietzmann T, Sánchez

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Association of E-selectin S128R polymorphism with hereditary breast carcinoma susceptibility in Turkish patients without BRCA1/2 germline mutations

-dependent lectin domain, an epidermal growth factor-like domain, regulatory elements, a transmembrane domain, and a short cytoplasmic tail [ 9 ]. Intracellular and extracellular interactions mediated by adhesion molecules are critical for the dissemination of metastatic tumor cells. Loss of cell-cell and/or cell-matrix adhesions allows malignant tumor cells to escape from their primary micro environment and to acquire a more motile and invasive phenotype, and thereby enables them to migrate to the other sides of the body. Consistent with this, E-selectin is involved in migration

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