Ioannis Zachos, Kalliopi Zachou, George N. Dalekos and Vasileios Tzortzis
considered a major risk factor carrying an increased morbidity and mortality in cirrhotic patients undergoing any kind of surgery, as they can often decompensate because of both anesthesia and surgery. [ 12 , 13 , 14 , 15 ] Diverse scores and indexes have been used for predicting the outcome of patients preoperatively, among which the American Society of Anesthesiologists (ASA) score and the age-adjusted Charlson Comorbidity Index (aaCCI) are the most validated for the pre- and perioperative evaluation. [ 14 , 15 , 16 ] However, in cirrhotic patients, the Child
Nikolaos-Dimitrios Pantzaris, Christina Platanaki, Charalampos Pierrako, Vasilios Karamouzos and Dimitrios Velissaris
Sepsis and the related multiple organ failure remains a worldwide problem leading to high morbidity and mortality rates. The currently available organ failure scoring systems, such as the Sequential Organ Failure Assessment (SOFA), the Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Simplified Acute Physiology II (SAPS II) scores are useful in the assessment of organ dysfunction over time and have been established as clinically useful indexes of severity and prognosis. The neutrophil-to-lymphocyte ratio (NLR) calculated
Shahinul Alam, Mohammad Jahid Hasan, Md. Abdullah Saeed Khan, Mahabubul Alam and Nazmul Hasan
progression to cirrhosis or hepatocellular carcinoma (HCC). At present, the resolution of the histological findings of NASH is now approved as a surrogate endpoint. The major treatment offered for NAFLD remains lifestyle changes including weight reduction by a healthy diet and performing regular physical activity. [ 12 , 13 ] It is evident that improvements of liver histology in NASH can be achieved through losing a certain amount of weight. [ 14 ] Promrat et al . in his RCT showed that almost 7–10% of weight reduction can improve the NAFLD activity score (NAS) and its
Herbert Spapen, Johan van Laethem, Maya Hites, An Verdoodt, Marc Diltoer and Patrick M. Honoré
in all patients: age, gender, Acute Physiology and Chronic Health Evaluation (APACHE) II score, Sequential Organ Failure Assessment (SOFA) score, comorbidities, concomitant antibiotic therapy, body mass index, and type/MIC of the causative pathogen. Occurrence of acute kidney injury (AKI) was assessed based on serum creatinine values recorded before the start of CVVH, 2 days after withdrawing CVVH, and at hospital discharge in survivors. Values were stratified according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria and duration of COL therapy
J. David Spence, Chrysi Bogiatzi, Mariya Kuk, George K. Dresser and Daniel G. Hackam
evaluate resistance to medication. We, therefore, developed a Medication Intensity Score and a Hypertension Resistance Score to assess the effect of eplerenone on resistance to concomitant medication.
Patients and methods
Patients being followed in our hypertension clinics (Drs. Dresser and Hackam) and stroke prevention clinics (Drs. Spence and Hackam) with a history of resistant hypertension that had led to assessment of plasma renin and aldosterone were screened for inclusion based on the previous levels of plasma aldosterone. Plasma
ultrasonic images of lungs and pleura. The results showed that when the patients had high WELLS scores (i.e., high PE probability), the specificity of the diagnosis is extremely high if the transthoracic ultrasonography found typical signs of PE; when the patients had low WELLS scores (i.e., low PE probability), the negative predictive value is extremely high if the transthoracic ultrasonography showed a negative result or only a small amount of typical PE signs.[ 7 ] Another study performed contrast-enhanced ultrasonography on the infarcted lung tissues of patients with
Amal Ahmed Mohamed, Eman R. Abd Almonaem, Amira I. Mansour, HebatAllah Fadel Algebaly, Rania Abdelmonem Khattab and Yasmine S. El Abd
encephalopathy and ascites, which is confirmed by ultrasound) and biochemical markers analysis, including serum aspartate aminotransferase (AST), alanine transaminase (ALT), serum bilirubin concentration, albumin, INR, hepcidin, and body iron content markers, including iron and ferritin concentrations. Patients were classified based on Child Pugh score: 31 patients with score A and 19 patients with score B and C. The biochemical serum tests were performed using Biosystem A15 autoanalyzer (Biosystems S.A., Barcelona) using appropriate kits. Serum hepcidin was measured using DRG
Aysegul Kahraman, Hakan Akdam, Alper Alp, Mustafa Ahmet Huyut, Cagdas Akgullu, Tuba Balaban, Fadime Dinleyen, Aynur Topcu, Husniye Gelmez, Nevin Atakan, Harun Akar and Yavuz Yenicerioglu
factors for higher mortality at the highest levels of spkt/V in haemodialysis patients. Nephrol Dial Transplant 2003; 18: 1339-1344.
24. Agroyannis B, Fourtounas C, Tzanatos H, et al. Relationship between interdialytic weight gain and acid-base status in hemodialysis by bicarbonate. Artif Organs 2002; 26: 385-387.
25. Janardhan V, Soundararajan P, Rani NV, et al. Prediction of Malnutrition Using Modified Subjective Global Assessmentdialysis Malnutrition Score in Patients on Hemodialysis. Indian J Pharm Sci 2011; 73: 38
Des Crowley, Walter Cullen, Eamon Laird, John S. Lambert, Tina Mc Hugh, Carol Murphy and Marie Claire Van Hout
population ranges from 62-81% [ 42 , 43 ] with risk factors similar to those reported elsewhere. These are injecting drug use, [ 42 , 43 - 47 ] frequency and length of time injecting, [ 45 , 48 , 49 ] needle sharing and having a history of imprisonment. [ 45 ] Low uptake of screening and follow up assessments are also reported [ 51 - 53 ] In Ireland, the treatment with DAAs is restricted to those with more advanced liver disease, determined by fibroscan score, with current guidelines identifying those with scores of > 8.5 kPa as being eligible for the treatment
Rafael Torres-Valadez, Sonia Roman, Alexis Jose-Abrego, Maricruz Sepulveda-Villegas, Claudia Ojeda-Granados, Ingrid Rivera-Iñiguez and Arturo Panduro
regardless of etiology. Finally, the diagnostic values of these biochemical parameters were compared with scores for the detection of liver fibrosis in Table 6 . In general, the sensitivity and specificity values were similar, fundamentally with the GPRI-Score and the FORNS-Index, but the PPV and concordance values were higher as compared to the other scores.
Cut-off values and ROC curve of biochemical parameters related to advanced liver damage using TE