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Management of patients with liver cirrhosis and invasive bladder cancer: A case-series

considered a major risk factor carrying an increased morbidity and mortality in cirrhotic patients undergoing any kind of surgery, as they can often decompensate because of both anesthesia and surgery. [ 12 , 13 , 14 , 15 ] Diverse scores and indexes have been used for predicting the outcome of patients preoperatively, among which the American Society of Anesthesiologists (ASA) score and the age-adjusted Charlson Comorbidity Index (aaCCI) are the most validated for the pre- and perioperative evaluation. [ 14 , 15 , 16 ] However, in cirrhotic patients, the Child

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Neutrophil-to-lymphocyte ratio relation to sepsis severity scores and inflammatory biomarkers in patients with community-acquired pneumonia: A case series

Introduction Sepsis and the related multiple organ failure remains a worldwide problem leading to high morbidity and mortality rates. The currently available organ failure scoring systems, such as the Sequential Organ Failure Assessment (SOFA), the Acute Physiology and Chronic Health Evaluation II (APACHE II) and the Simplified Acute Physiology II (SAPS II) scores are useful in the assessment of organ dysfunction over time and have been established as clinically useful indexes of severity and prognosis. The neutrophil-to-lymphocyte ratio (NLR) calculated

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Effect of weight reduction on histological activity and fibrosis of lean nonalcoholic steatohepatitis patient

progression to cirrhosis or hepatocellular carcinoma (HCC). At present, the resolution of the histological findings of NASH is now approved as a surrogate endpoint. The major treatment offered for NAFLD remains lifestyle changes including weight reduction by a healthy diet and performing regular physical activity. [ 12 , 13 ] It is evident that improvements of liver histology in NASH can be achieved through losing a certain amount of weight. [ 14 ] Promrat et al . in his RCT showed that almost 7–10% of weight reduction can improve the NAFLD activity score (NAS) and its

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Treatment of ventilator-associated pneumonia with high-dose colistin under continuous veno-venous hemofiltration

in all patients: age, gender, Acute Physiology and Chronic Health Evaluation (APACHE) II score, Sequential Organ Failure Assessment (SOFA) score, comorbidities, concomitant antibiotic therapy, body mass index, and type/MIC of the causative pathogen. Occurrence of acute kidney injury (AKI) was assessed based on serum creatinine values recorded before the start of CVVH, 2 days after withdrawing CVVH, and at hospital discharge in survivors. Values were stratified according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria and duration of COL therapy

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Effects of eplerenone on resistance to antihypertensive medication in patients with primary or secondary hyperaldosteronism

evaluate resistance to medication. We, therefore, developed a Medication Intensity Score and a Hypertension Resistance Score to assess the effect of eplerenone on resistance to concomitant medication. Patients and methods Study population Patients being followed in our hypertension clinics (Drs. Dresser and Hackam) and stroke prevention clinics (Drs. Spence and Hackam) with a history of resistant hypertension that had led to assessment of plasma renin and aldosterone were screened for inclusion based on the previous levels of plasma aldosterone. Plasma

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Clinical value of ultrasonography in diagnosis of pulmonary embolism in critically ill patients

ultrasonic images of lungs and pleura. The results showed that when the patients had high WELLS scores (i.e., high PE probability), the specificity of the diagnosis is extremely high if the transthoracic ultrasonography found typical signs of PE; when the patients had low WELLS scores (i.e., low PE probability), the negative predictive value is extremely high if the transthoracic ultrasonography showed a negative result or only a small amount of typical PE signs.[ 7 ] Another study performed contrast-enhanced ultrasonography on the infarcted lung tissues of patients with

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Importance of studying the levels of hepcidin and vitamin D in Egyptian children with chronic hepatitis C

encephalopathy and ascites, which is confirmed by ultrasound) and biochemical markers analysis, including serum aspartate aminotransferase (AST), alanine transaminase (ALT), serum bilirubin concentration, albumin, INR, hepcidin, and body iron content markers, including iron and ferritin concentrations. Patients were classified based on Child Pugh score: 31 patients with score A and 19 patients with score B and C. The biochemical serum tests were performed using Biosystem A15 autoanalyzer (Biosystems S.A., Barcelona) using appropriate kits. Serum hepcidin was measured using DRG

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Impact of Interdialytic Weight Gain (IDWG) on Nutritional Parameters, Cardiovascular Risk Factors and Quality of Life in Hemodialysis Patients

factors for higher mortality at the highest levels of spkt/V in haemodialysis patients. Nephrol Dial Transplant 2003; 18: 1339-1344. 24. Agroyannis B, Fourtounas C, Tzanatos H, et al. Relationship between interdialytic weight gain and acid-base status in hemodialysis by bicarbonate. Artif Organs 2002; 26: 385-387. 25. Janardhan V, Soundararajan P, Rani NV, et al. Prediction of Malnutrition Using Modified Subjective Global Assessmentdialysis Malnutrition Score in Patients on Hemodialysis. Indian J Pharm Sci 2011; 73: 38

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Exploring patient characteristics and barriers to Hepatitis C treatment in patients on opioid substitution treatment attending a community based fibro-scanning clinic

population ranges from 62-81% [ 42 , 43 ] with risk factors similar to those reported elsewhere. These are injecting drug use, [ 42 , 43 - 47 ] frequency and length of time injecting, [ 45 , 48 , 49 ] needle sharing and having a history of imprisonment. [ 45 ] Low uptake of screening and follow up assessments are also reported [ 51 - 53 ] In Ireland, the treatment with DAAs is restricted to those with more advanced liver disease, determined by fibroscan score, with current guidelines identifying those with scores of > 8.5 kPa as being eligible for the treatment

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Early detection of liver damage in Mexican patients with chronic liver disease

regardless of etiology. Finally, the diagnostic values of these biochemical parameters were compared with scores for the detection of liver fibrosis in Table 6 . In general, the sensitivity and specificity values were similar, fundamentally with the GPRI-Score and the FORNS-Index, but the PPV and concordance values were higher as compared to the other scores. Table 5 Cut-off values and ROC curve of biochemical parameters related to advanced liver damage using TE Variable AUCs P -value Optimal Sensitivity Specificity PPV NPV Concordance

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