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“Pulling hair out of the head” - the importance of traumatic family events in the development and maintenance of trichotillomania symptoms - case report

Abstract

Introduction: Trichotillomania is a mental disorder characterized by a repetitive and compulsive hair pulling, classified in ICD-10 to a group of habit and impulse disorders, and in the DSM-5 to the group of obsessive-compulsive disorders.

Aim: The aim of the study is to present on the basis of case study:1). the importance of traumatic family experiences in releasing as well as maintaining the symptoms of Trichotillomania, 2). comprehensive medical care, the application of which has resulted in a beneficial therapeutic effect.

Results: In the described case of 16-year-old patient, Trichotillomania was triggered by traumatic events related to lack of support and family stabilization resulting from parental disputes and grandfather’s death, when she was 11 years old. The subsequent years of her life, in spite of the divorce of her parents and their separate residence, abounded in periods of turbulent quarrels between the parents in which she was involved. Each time this type of incident was associated with the recurrence of behavior associated with Trichotil-lomania, the course of which was more severe with the occurrence of self-harm and suicidal thoughts.

Conclusions: 1. In the described case, traumatic events and pathological relations of the immediate family members were not only thetriggering factor, but also maintaining the Trichotillomania symptoms. 2. In accordance with the guidelines of Trichotillomania Learning Center-Scientific Advisory Board (2008), the use of a comprehensive treatment including both the patient - individual psycho-therapy (especially cognitive-behavioral therapy) and pharmacotherapy, as well as her family (family psychotherapy, family mediation, workshops for parents), brought about positive therapeutic effects.

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The role of retinoic acid receptors and their cognate ligands in reproduction in a context of triorganotin based endocrine disrupting chemicals

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Mechanisms promoting and inhibiting the process of proteasomal degradation of cells

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Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance

and epithelial mesenchymal transformation of high glucose induced-podocytes. Exp Ther Med 16, 1095–1102, 2018. Chen J, Van Gulden S, McGuire TL, Fleming AC, Oka C, Kessler JA, Peng CY. BMP-responsive protease HtrA1 is differentially expressed in astrocytes and regulates astrocytic development and injury response. J Neurosci 38, 3840–3857, 2018. Chevet E, Hetz C, Samali A. Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis. Cancer Discov 5, 586–597, 2015. Contois LW, Akalu A, Caron JM, Tweedie E, Cretu A, Henderson T, Liaw L

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Effect of the autonomic nervous system on cancer progression depends on the type of tumor: solid are more affected then ascitic tumors

, Lutgendorf SK, Sood AK. Neuroendocrine influences on cancer progression. Brain Behav Immun 30 Suppl, S19–25, 2013. Bauman J, McVary K. Autonomic nerve development contributes to prostate cancer progression. Asian J Androl 15, 713–714, 2013. Bayon Lara AM, Landa Garcia I, Alcalde Escribano J, Rodriguez Dapena S, Ortega Medina L, Balibrea Cantero JL. Colonic carcinogenesis in vagotomyzed rats. Rev Esp Enferm Dig 93, 576–586, 2001. Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 3, 401–410, 2003. Bjelakovic G, Tasic T

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Neuronal morphology alterations in autism and possible role of oxytocin

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Psychological Support for Families During Crises (as exemplified by families members of Ukrainian war veterans)

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Multiple functions and essential roles of nuclear receptor coactivators of bHLH-PAS family

M. Development of stapled short helical peptides capable of inhibiting vitamin D receptor (VDR)-coactivator interactions. Bioorg Med Chem Lett 23, 4292-4296, 2013. Ding L, Yang L, Wang Z, Huang W. Bile acid nuclear receptor FXR and digestive system diseases. Acta Pharm Sin B5 135-144, 2015. D’Rozario M, Zhang T, Waddell EA, Zhang Y, Sahin C, Sharoni M, Hu T, Nayal M, Kutty K, Liebl F, Hu W, Marenda DR. Type I bHLH Proteins Daughterless and Tcf4 Restrict Neurite Branching and Synapse Formation by Repressing Neurexin in Postmitotic

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Review paper. Gluten-related disorders and schizophrenia - potential linking mechanisms, diagnostic and therapeutic challenge

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Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells

. Nanomedicine 6, 714-729, 2010. Kolena J, Scsukova S, Jezova M, Furdova J, Tatara M, Jasem P. Eff ect of phospholipids on the reconstitution and thermal stability of delipidated rat ovarian luteinizing hormone/human chorionic gonadotropin receptors in proteoliposomes. Mol Cell Endocrinol 113, 53-60, 1995. Lu X, Kong X, Lobie PE, Chen Ch, Zhu T. Nanotoxicity: a growing need for study in the endocrine system. Small 9, 1654-1671, 2013. Moritz M, Gezske-Moritz M. Recent developments in the application of polymeric nanoparticles as

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