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The role of neuronal apoptosis inhibitory protein (NAIP) in acute myeloid leukemia patients

cells. Nakagawa et al. studied NAIP mRNA expression in BM samples from 13 healthy individuals, 9 patients with AML, 7 with acute lymphoblastic leukemia (ALL) and 8 with acute mixed linage leukemia (AMLL) by quantitative RT-PCR. They found that NAIP expression was present in all examined cases and was higher in AML, ALL, and AMLL than in healthy BM samples [ 26 ]. The present study is the first to assess the expression of NAIP protein in AML cells using cytometry. It identified NAIP expression in 98% of AML patients with a range 1–79.6%. The presence of NAIP mRNA

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Selected factors influencing angiogenesis and hematopoietic niche

mRNA degradation? The deepening mystery of microRNA function Cell Res 2012 9 1322 4 10.1038/cr.2012.80 [65] Fan SJ, Li HB, Cui G, et al. miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia. Leuk Res 2016;41:62–70. doi: 10.1016/j. leukres.2015.11.016. 10.1016/j.leukres.2015.11.016 Fan SJ Li HB Cui G miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia Leuk Res 2016 41 62 70 10.1016/j.leukres.2015

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