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Thitima Ngoenmak, Julintorn Somran, Chutima Phuaksaman and Jaruwat Khunrat
not specific and lacked of usual morphologic changes, especially microvesicular and macrovesicular steatosis, which have been described in galactosemia [ 13 , 14 ]. Therefore, many potential causes of neonatal hepatitis, including viral infection and metabolic disorders were excluded by investigations.
The appropriate treatment for an infant with galactosemia is to (1) eliminate any lactose-containing formula and breast feeding, and begin a formula such as a soy-based formula that contains no lactose as soon as possible, (2) monitor for signs of sepsis, and (3
biopsy using standard procedures with ultrasonography guidance. Data of all patients were recorded, including demographic data, anthropometric data and biochemical tests on the day of liver biopsy or within 2 weeks of the procedure. All patients were followed-up with the results of liver histological findings within the following 2 weeks. We used the histological findings of liver fibrosis as the criterion standard or index diagnosis.
The diagnosis of NAFLD was based on the following criteria: (1) liver biopsy showing steatosis in at least 5% of
Amal Ahmed Mohamed, Eman R. Abd Almonaem, Amira I. Mansour, HebatAllah Fadel Algebaly, Rania Abdelmonem Khattab and Yasmine S. El Abd
stores upregulate hepcidin expression, while anemia, hypoxia, and oxidative stress downregulate it. [ 4 , 5 ] Hepcidin is recognized as a biomarker for systemic inflammatory states because of upregulation by inflammatory cytokines. [ 3 , 4 , 5 , 6 ] Patients with chronic liver disease (CLD) usually have iron overload, especially hepatitis C virus (HCV), steatosis, and cirrhotic liver; this iron produces free oxygen radicals with harmful effects on various organs. This consensus pay attention to studying the overall iron homeostasis and the regulatory mechanisms
Aleksandra Klisic, Gordana Kocic, Nebojsa Kavaric, Radmila Pavlovic, Ivan Soldatovic and Ana Ninic
without MetS (n=58) and a group with MetS (n=51).
Exclusion criteria for all potential participants were: hsCRP >10 mg/L, acute inflammatory disease, diabetes mellitus, liver diseases other than steatosis, kidney diseases, malignant diseases, gout, ethanol consumption >20 g/day, pregnancy, as well as unwillingness to participate in the study.
The Ethical Committee of the Primary Health Care Center in Podgorica, Montenegro approved the study protocol. All the volunteers provided signed informed consent, and the research was carried out in compliance with the
Miroslav Zeman, Marek Vecka, František Perlík, Barbora Staňková, Robert Hromádka, Eva Tvrzická, Jakub Širc, Jakub Hrib and Aleš Žák
. L. Kashyap and V. S. Kamanna, Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease, Am. J. Physiol. Gastrointest. Liver Physiol. 306 (2014) G320-G327; DOI: 10.1152/ajpgi.00181.2013.
88. M. Hara, M. Kurano, K. Tsuneyama, K. Kikuchi, A. Takai, T. Matsushima and K. Tsukamoto, Nicotinic acid prevents and restores steatohepatitis together with amelioration of postprandial dyslipidemia, Arterioscler. Thromb. Vasc. Biol. 34 (2014) A601. American Heart Association (AHA