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Fifty-Five years of Pediatric Endocrinology and 50 years of the Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases in Slovenia / 55 Let Pediatrične Endokrinologije in 50 Let Kliničnega Oddelka Za Endokrinologijo, Diabetes in Presnovne Bolezni Pediatrične Klinike

-acting pegylated human GH in children with GH deficiency: a single-dose, dose-escalation trial investigating safety, tolerability, pharmacokinetics and pharmacodynamics. Eur J Endocrinol 2011; 165: 401-9. 5. Raivio T, Avbelj M, McCabe MJ, Romero CJ, Dwyer AA, Tommiska J. et al. Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia. J Clin Endocrinol Metab 2012; 97: E694-9. 6. Kotnik P, Keuper M, Wabitsch M, Fischer-Posovszky P. Interleukin-1β downregulates RBP4 secretion in human adipocytes. PLoS

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Trends in vascular pharmacology research in the Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, Bratislava

, Kriška M, Kovalčík V. (1978). Bayliss myogenic response in the isolated ductus arteriosus of guinea-pig and rabbit fetuses. Experientia   34 : 745-746. Turnheim K. (2003). When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol   38 : 843-853. Varga Z, Kriška M, Kristová V, Hudec. (2010). Prescription of NSAIDs and risk of cardiovascular adverse effects in hospitalized patients. Rheumatologia 24 : 87-90. Vojtko R., Villaris R., Petrová M., Líšková S

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Analysis of Protein Adducts as Biomarkers of Short-Term Exposure to Ethylene Oxide and Results of Follow-Up Biomonitoring

, Törnqvist M, Kessler W, Ehrenberg L. Pharmacokinetics of ethylene oxide in man; body burden with ethylene oxide and hydroxyethylation of hemoglobin due to endogenous and environmental ethylene. Arch Toxicol 1992;66:157-63.

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Evaluation of Oxime K203 as Antidote in Tabun Poisoning

colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1960;7:88-95. Thiermann H, Mast U, Klimmek R, Eyer P, Hibler A, Pfab R, Flegenhauer N, Zilker T. Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients. Hum Exp Toxicol 1997;16:473-80. Eddleston M, Szinicz L, Eyer P, Buckley N. Oximes in acute organophosphorus pesticide poisoning: a systemic review of clinical trials. Qjm-Mon J Assoc Phys 2002

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Evaluation of Teratogenic Activity of Antiepileptic Drug Lamotrigine in Mouse Fetuses

, Bastaki S, et al. Experimental studies on reproductive toxicologic effects of lamotrigine in mice. Birth Defects Res B Dev Reprod Toxicol 2003; 68(5): 428-38. 30. Ohman I, Vitols S, Tomson T. Lamotrigine in pregnancy: pharmacokinetics during delivery, in the neonate, and during lactation. Epilepsia 2000; 41(6): 709-13. 31. Tunbridge EM, Attenburrow MJ, Gardiner A, et al. Biochemical and genetic predictors and correlates of response to lamotrigine and folic acid in bipolar depression: Analysis of the CEQUEL clinical trial. Bipolar Disorders 2017; 19(6): 477

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Photochemical toxicity of drugs intended for ocular use

. Chromatographia 2009;69(Supplement):115-22. doi: 10.1365/s10337-009-1082-3 21. Epaulard O, Saint-Raymond C, Villier C, Charles J, Roch N, Beani JC, Leccia MT. Multiple aggressive squamous cell carcinomas associated with prolonged voriconazole therapy in four immunocompromised patients. Clin Microbiol Infect 2010;16:1362-4. doi: 10.1111/j.1469-0691.2009.03124.x 22. Scholz I, Oberwittler H, Riedel KD, Burhenne J, Weiss J, Haefeli WE, Mikus G. Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation

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Platinum Complexes with Edda (Ethylenediamine -N, N - Diacetate) Ligands as Potential Anticancer Agents

-22. 21. Hamilton, G., & Olszewski, U. (2013). Picoplatin pharmacokinetics and chemotherapy of non-small cell lung cancer. Drug Evaluations. 9(10), 1381-1390. 22. Jakupec, M.A., Galanski, M., & Keppler, B.K. (2003). Tumor inhibiting platinum complexes- state of the art and future perspectives. Rev Physiol Biochem Pharmacol. 146, 1-53. 23. Armand, J.P., Bolgie, V., Raymond, E., Fizazi, K., Faivre, S., & Ducreux, M. (2000). Oxaliplatin in colorectal cancer: an overview. Semin Oncol., 27, 96-104. 24. Kelland, L. (2007). The

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The Wnt Signalling Pathways: A Short Review and Specific Roles in Bone Biochemistry

-related stimulus toward a cure for osteoporosis, Frontiers in Endocrinology, 2015; 6:1-4 39. Fulciniti M, Tassone P, Hideshima T et al. - Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma, Blood Journal, 2009; 114:371-379 40. Goldstein SD, Trucco M, Guzman WB et al. - A monoclonal antibody against the Wnt signaling inhibitordickkopf-1 inhibits osteosarcoma metastasis in a preclinical model, 2016; Oncotarget, 7:21114-21123 41. Betts AM, Clark TH, Yang J et al. – The application of target information and preclinical pharmacokinetic

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Efficacy of Intravenous Administration of Iron Sucrose for Treatment of Iron Deficiency Anaemia in Patients With Abnormal Uterine Bleeding

-2115(03)00113-1 Hashmi Z, Bashir G, Azeem P, Shah S. Effectiveness of intravenous iron sucrose complex versus intramuscular iron sorbitol in iron deficiency anemia Ann Pak Inst Med Sci 2006; 2: 188-91. Petewusnyk G, Huch R, Huch A, Breymann C. Parenteral iron therapy in obstetrics: 8 years experience with iron-sucrose complex. Br J Nutr 2002;88:3-10. Danielson B G. Structure, Chemistry, and Pharmacokinetics of Intravenous Iron Agents J Am Soc Nephrol 2004; 15: 93

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Changes In QTc Interval Duration Among Heroin Addicts On Methadone Treatment

. Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence. Clin. Pharmacokinet.41, 1153–1193 (2002). 8. Gerber, J.G., Rhodes, R.J. & Gal, J. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. Chirality 16, 36–44 (2004). 9. Crettol, S. et al. Methadone enantiomer plasma levels CYP2B6, CYP2C19 and CYP2C9 genotypes, and response to treatment. Clin. Pharmacol. Ther. 78, 593–604 (2005). 10. McCance-Katz EF, Sullivan LE, Nallani S. Drug interactions of clinical

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