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Vitamin D Immunomodulatory Potential in Multiple Sclerosis

. Pugliatti M, Sotgiu S, Rosati G. The worldwide prevalence of multiple sclerosis. Clin Neurol Neurosur 2002;104:182-91. 9. Cantorna MT. Vitamin D and multiple sclerosis: an update. Nutr Rev 2008;66(2):S135- S138. 10. Peeien E, Knippenberg S, Muris A-H, et al. Effects of vitamin D on the peripheral adaptive immune system: a review. Autoimmunity Rev 2011;10(12):733-43. 11. Mellanby RJ, Thomas DC, Lamb J. Role of regulatory T-cells in autoimmunity. Clin Sci 2009;116:639-49. 12. Lysandropoulos AP, Jaquiery E

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Overview of Deep Learning Models in Biomedical Domain with the Help of R Statistical Software

al. “Identifying medical diagnoses and treatable diseases by image-based deep learning.” Cell 172, no. 5 (2018): 1122-1131. 12. Gerard, S. E., Patton, T. J., Christensen, G. E., Bayouth, J. E., & Reinhardt, J. M. (2018). FissureNet: A deep learning approach for pulmonary fissure detection in CT images. IEEE transactions on medical imaging. 1-1. 13. Hinton, G. (2018). Deep learning-a technology with the potential to transform health care. JAMA. 320(11):1101-1102. 14. Chen, M., Hao, Y., Hwang, K., Wang, L., & Wang, L

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Effects of Taurine Against Histomorphological and Ultrastructural Changes in the Testes of Mice Exposed to Aluminium Chloride

agents in cAMP production and in steroidogenic response of isolated rat Leydig cells. Biol Cell 1984;52:259-66. PMID: 6273135 47. Dobashi M, Fujisawa M, Yamazaki T, Okuda Y, Kanzaki M, Tatsumi N, Tsuji T, Okada H, Kamidono S. Inhibition of steroidogenesis in Leydig cells by exogenous nitric oxide occurs independently of steroidogenic acute regulatory protein (star) mRNA. Arch Androl 2001;47:203-9. PMID: 11695844 48. Kostić TS, Andrić SA, Marić D, Kovačević RZ. Inhibitory effects of stress-activated nitric oxide on antioxidant enzymes and

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Investigation of circulating serum microRNA-328-3p and microRNA-3135a expression as promising novel biomarkers for autism spectrum disorder

Casallo G Gene and miRNA expression profiles in autism spectrum disorders Brain Res 2011 1380 85 97 13 Sarachana T, Zhou R, Chen G, Manji HK, Hu VW. Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med. 2010; 2(4): 23. 10.1186/gm144 Sarachana T Zhou R Chen G Manji HK Hu VW Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of

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Endocrine and Metabolic Effects of Adipose Tissue in Children and Adolescents / Endokrina in Presnovna Funkcija Maščobnega Tkiva Pri Otrocih in Mladostnikih

of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002; 110: 1093-103. 7. Fiorenza CG, Chou SH, Mantzoros CS. Lipodystrophy: pathophysiology and advances in treatment. Nat Rev Endocrinol 2011; 7: 137-50. 8. Hebebrand J, Muller TD, Holtkamp K, Herpertz-Dahlmann B. The role of leptin in anorexia nervosa: clinical implications. Mol Psychiatry 2007; 12: 23-35. 9. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce

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Fatigue in Patients with Autoimmune Thyroid Diseases

four models predicting fatigue in multiple sclerosis. Arch Clin Neuropsychol 2005; 20: 631-46. 18. Zivancevic-Simonovic S, Djukic A, Arsenijevic N, Dimitrijevic Lj. Autoimunska bolest štitaste žlezde:patogeneza Gravesove bolesti i Hashimoto tireoiditisa. Medicus 2003; 4: 21-6. 19. Sinclair D. Clinical and laboratory aspects of thyroid autoantibodies. Ann Clin Biochem 2006; 43: 173-83. 20. McLachlan SM, Nagayama Y, Pichurin PN, et al. The link between Graves’ disease and Hashimoto’s thyroiditis: A role for regulatory T

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Association of the MMP7 –181A>G promoter polymorphism with early onset of chronic obstructive pulmonary disease

-ligand, pro-tumor necrosis factor (TNF), and E-cadherin [ 10 , 11 ]. The production of the enzyme is highly up-regulated by injury or exposure to bacteria, stimulating cell migration and coordinating the inflammatory response [ 12 , 13 , 14 ]. Thus, MMP-7 participates in the processes of defense, repair and inflammation. In the promoter of the gene of MMP-7 an A>G transition has been identified as a functional polymorphism ( MMP7 –181A>G; rs11568818). The polymorphism has been shown to modulate transcriptional activity by influencing the binding of nuclear regulatory

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Complement Factor H Y403H Polymorphism in the Turkish Population

common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to agerelated macular degeneration. Proc Natl Acad Sci USA. 2005; 102(20): 7227-7232. Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA. Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005; 308(5720): 419-421. Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS

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Glutathionylation: a regulatory role of glutathione in physiological processes

References 1. Josephy PD. Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. Hum Genomics Proteomics 2010;2010:876940. doi: 10.4061/2010/876940 2. Wu D, Meydani SN, Sastre J, Hayek M, Meydani M. In vitro glutathione supplementation enhances interleukin-2 production and mitogenic response of peripheral blood mononuclear cells from young and old subjects. J Nutr 1994;124:655-63. PMID: 8169657 3. Espinosa-Diez C, Miguel V, Mennerich D, Kietzmann T, Sánchez

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Oral Disorders in Sjögren’s Syndrome

salivary gland cells by IL-18. J Immunol. 181: 2898-2906. 14. Alunno A, Carubbi F, Bistoni O, Caterbi S, Bartoloni E, Mirabelli G, Cannarile F, Cipriani P, Giacomelli R, Gerli R. (2015) T Regulatory and T Helper 17 Cells in Primary Sjögren’s Syndrome: Facts and Perspectives. Mediators Inflamm. 243723 15. Fogel O, Riviere E, Seror R, Nocturne G, Boudaoud S, Ly B, Gottenberg JE,Le Guern V, Dubost J-J, Nititham J, Taylor KE, Chanson P, Dieudé P, Criswell LA, Jagla B, Thai A,Mingueneau M, Mariette X, Miceli-Richard C. (2017) Role of the IL-12

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