regression analysis was made for prediction of all postoperative infections. It included ASA score, type of surgical procedure, duration of surgery and perioperative transfusion. Independent risk factors for infections were found to be duration of surgery (odds ratio [OR] 1.63, 95% CI 1.14–2.40, p = 0.01) and perioperative transfusion (OR 1.10, 95% CI 1.02–1.19, p = 0.014). The expectedodds for infection increased with every hour of surgery by 63% (95% CI 14–140%) or with every 100mL of transfusion by 10% (95% CI 2–19%).
The values of all
Sabrina Bimonte, Maddalena Leongito, Vincenza Granata, Antonio Barbieri, Vitale del Vecchio, Michela Falco, Aurelio Nasto, Vittorio Albino, Mauro Piccirillo, Raffaele Palaia, Alfonso Amore, Raimondo di Giacomo, Secondo Lastoria, Sergio Venanzio Setola, Roberta Fusco, Antonella Petrillo and Francesco Izzo
-operative PET examination was lower in respect to pre-operative evaluations. No serious side effects for the patients were observed. In addition, pain reduction of patients (evaluated by VAS-score) was reported immediately after the ECT treatment compared to pre-operative status. Preliminary data on feasibility and safety of the ECT treatment on patients with locally advanced cancer were reported by Granata et al. 15 For a significant number of patients, a reduced diameter and tumourigenicity of the lesions associated with good clinical parameters were reported.
Jinwei Luan, Xianglan Li, Rutao Guo, Shanshan Liu, Hongyu Luo and Qingshan You
the interactions between the proteins encoded by the common DEGs. A required confidence (combined score) > 0.4 was used as the cut-off criterion. Subsequently, Cytoscape software 16 was used to visualize the PPI network.
ClueGO 17 in Cytoscape was used to conduct GO, KEGG and BioCarta enrichment analyses. Further, ClueGO divided terms into different functional groups based on the common genes involved in different terms. In our study, ClueGO was used for KEGG pathway enrichment analysis. A p-value < 0.05 was used as the cut-off criterion
Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE). 8 Patients were evaluated for disease control, survival, and late toxicities of radiotherapy at 2–3 month intervals for the first 2 years, at 3–6 month intervals between the third and fifth year. Late toxicities were assessed by the RTOG/EORTC late radiation morbidity scoring system. 9 At every visit fiber-optic endoscopy by an otolaryngologists has been done. CT scan of the neck was performed every 6 months in the first 2 years and annually thereafter.
OS and LRFFS were estimated using the Kaplan
within normal range. Patient underwent stereotactic radiotherapy of cerebral metastasis with dose 1 × 25 Gy after the fourth cycle and afterwards received two additional cycles of EMA-CO regimen with standard dose of metotrexate. To completely rule out the origin of the tumour in reproductive tract the vaginal total hysterectomy with bilateral salpingoectomy was performed after 6 cycles of chemotherapy and histopathological examination was negative.
According to FIGO clinical and prognostic staging patient had stage IV disease with high-risk score. 12 Brain MRI was
Irena Oblak, Monika Cesnjevar, Mitja Anzic, Jasna But Hadzic, Ajra Secerov Ermenc, Franc Anderluh, Vaneja Velenik, Ana Jeromen and Peter Korosec
was to evaluate the influence of anaemia on radiochemotherapy treatment outcome in patients with squamous cell carcinoma of the anal canal.
Patients and methods
One hundred consecutive patients (60 females and 40 males) with histologically confirmed squamous cell carcinoma of the anal canal were included in the retrospective study. They were treated at the Institute of Oncology Ljubljana from January 2003 till June 2013.
For performance status (PS) the scoring system of the World Health Organization (WHO) was used 19 , and for TNM staging the criteria of
Lei Du, Xin Xin Zhang, Lin Chun Feng, Jing Chen, Jun Yang, Hai Xia Liu, Shou Ping Xu, Chuan Bin Xie and Lin Ma
2014-048-01, and all eligible patients provided informed consent in written form.
Inclusion criteria were as follows: histologically proven type I and II NPC according to World Health Organization (WHO) criteria; stage I–IVa according to the Union for International Cancer Control (UICC) 2002 Staging System; aged between 15 and 75 years; Karnofsky performance status score ≥ 70; white blood cell count ≥ 3,500/μL, platelet count ≥ 100,000/μL, serum creatinine concentration < 133 umol/L, and liver transaminase level < 2.0 times of the upper normal value. Exclusion
Zdenek Rehak, Andrea Sprlakova-Pukova, Zbynek Bortlicek, Zdenek Fojtik, Tomas Kazda, Marek Joukal, Renata Koukalova, Jiri Vasina, Jana Eremiasova and Petr Nemec
trochanteric bursae, and the glenohumeral or hip joints. 3 , 4 The diagnosis of PMR is made primarily on clinical grounds and is bolstered by laboratory evidence of an acute phase reaction. There is no single diagnostic test for PMR, but several diagnostic and classification criteria have been suggested by some groups. 5 – 9 Each set of criteria has advantages and disadvantages. A PMR-associated ultrasound lesion(s) in the shoulders and/or hips is currently acknowledged as diagnostic criteria for the scoring algorithm in the differential diagnosis of PMR. 10 However
Arndt-Christian Müller, Johannes Mischinger, Theodor Klotz, Bernd Gagel, Gregor Habl, Gencay Hatiboglu and Michael Pinkawa
progression through the full thickness of the Denonvilliers’ fascia. 26
After successful injection, the benefit for the patients was measured by acute toxicity scores and by radiation planning parameters (dose-volume histograms). In brief, the theoretical benefit of an additional space between prostate and rectum translated into improved radiation treatment plans with approximately 10% reduction in relevant high-dose areas (dose level from 40–70Gy). 8 These improved radiation treatment plans with lower rectal doses converted into reduced acute toxicity rates. Grade 2