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Perioperative increase in neutrophil CD64 expression is an indicator for intra-abdominal infection after colorectal cancer surgery

regression analysis was made for prediction of all postoperative infections. It included ASA score, type of surgical procedure, duration of surgery and perioperative transfusion. Independent risk factors for infections were found to be duration of surgery (odds ratio [OR] 1.63, 95% CI 1.14–2.40, p = 0.01) and perioperative transfusion (OR 1.10, 95% CI 1.02–1.19, p = 0.014). The expectedodds for infection increased with every hour of surgery by 63% (95% CI 14–140%) or with every 100mL of transfusion by 10% (95% CI 2–19%). Biomarkers analysis The values of all

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Electrochemotherapy in pancreatic adenocarcinoma treatment: pre-clinical and clinical studies

-operative PET examination was lower in respect to pre-operative evaluations. No serious side effects for the patients were observed. In addition, pain reduction of patients (evaluated by VAS-score) was reported immediately after the ECT treatment compared to pre-operative status. Preliminary data on feasibility and safety of the ECT treatment on patients with locally advanced cancer were reported by Granata et al. 15 For a significant number of patients, a reduced diameter and tumourigenicity of the lesions associated with good clinical parameters were reported. These

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Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

the interactions between the proteins encoded by the common DEGs. A required confidence (combined score) > 0.4 was used as the cut-off criterion. Subsequently, Cytoscape software 16 was used to visualize the PPI network. ClueGO analysis ClueGO 17 in Cytoscape was used to conduct GO, KEGG and BioCarta enrichment analyses. Further, ClueGO divided terms into different functional groups based on the common genes involved in different terms. In our study, ClueGO was used for KEGG pathway enrichment analysis. A p-value < 0.05 was used as the cut-off criterion

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The outcome of the first 100 nasopharyngeal cancer patients in thailand treated by helical tomotherapy

Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE). 8 Patients were evaluated for disease control, survival, and late toxicities of radiotherapy at 2–3 month intervals for the first 2 years, at 3–6 month intervals between the third and fifth year. Late toxicities were assessed by the RTOG/EORTC late radiation morbidity scoring system. 9 At every visit fiber-optic endoscopy by an otolaryngologists has been done. CT scan of the neck was performed every 6 months in the first 2 years and annually thereafter. OS and LRFFS were estimated using the Kaplan

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Primary pulmonary choriocarcinoma

within normal range. Patient underwent stereotactic radiotherapy of cerebral metastasis with dose 1 × 25 Gy after the fourth cycle and afterwards received two additional cycles of EMA-CO regimen with standard dose of metotrexate. To completely rule out the origin of the tumour in reproductive tract the vaginal total hysterectomy with bilateral salpingoectomy was performed after 6 cycles of chemotherapy and histopathological examination was negative. According to FIGO clinical and prognostic staging patient had stage IV disease with high-risk score. 12 Brain MRI was

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The impact of anaemia on treatment outcome in patients with squamous cell carcinoma of anal canal and anal margin

was to evaluate the influence of anaemia on radiochemotherapy treatment outcome in patients with squamous cell carcinoma of the anal canal. Patients and methods One hundred consecutive patients (60 females and 40 males) with histologically confirmed squamous cell carcinoma of the anal canal were included in the retrospective study. They were treated at the Institute of Oncology Ljubljana from January 2003 till June 2013. For performance status (PS) the scoring system of the World Health Organization (WHO) was used 19 , and for TNM staging the criteria of

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Treatment of nasopharyngeal carcinoma using simultaneous modulated accelerated radiation therapy via helical tomotherapy: a phase II study

2014-048-01, and all eligible patients provided informed consent in written form. Inclusion criteria were as follows: histologically proven type I and II NPC according to World Health Organization (WHO) criteria; stage I–IVa according to the Union for International Cancer Control (UICC) 2002 Staging System; aged between 15 and 75 years; Karnofsky performance status score ≥ 70; white blood cell count ≥ 3,500/μL, platelet count ≥ 100,000/μL, serum creatinine concentration < 133 umol/L, and liver transaminase level < 2.0 times of the upper normal value. Exclusion

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PET/CT imaging in polymyalgia rheumatica: praepubic 18F-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis

trochanteric bursae, and the glenohumeral or hip joints. 3 , 4 The diagnosis of PMR is made primarily on clinical grounds and is bolstered by laboratory evidence of an acute phase reaction. There is no single diagnostic test for PMR, but several diagnostic and classification criteria have been suggested by some groups. 5 – 9 Each set of criteria has advantages and disadvantages. A PMR-associated ultrasound lesion(s) in the shoulders and/or hips is currently acknowledged as diagnostic criteria for the scoring algorithm in the differential diagnosis of PMR. 10 However

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Interdisciplinary consensus statement on indication and application of a hydrogel spacer for prostate radiotherapy based on experience in more than 250 patients

progression through the full thickness of the Denonvilliers’ fascia. 26 After successful injection, the benefit for the patients was measured by acute toxicity scores and by radiation planning parameters (dose-volume histograms). In brief, the theoretical benefit of an additional space between prostate and rectum translated into improved radiation treatment plans with approximately 10% reduction in relevant high-dose areas (dose level from 40–70Gy). 8 These improved radiation treatment plans with lower rectal doses converted into reduced acute toxicity rates. Grade 2

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Similar complication rates for irreversible electroporation and thermal ablation in patients with hepatocellular tumors

summarized in Table 1 . Table 1 Patient and tumor characteristics of the RFA/MWA and IRE group RFA/MWA (n = 117) IRE (n = 47) p-value Male, n (%) 98 (83.8) 46 (97.9) 0.013 Age median (IQR) 66 (14) 71 (15) 0.239 range 45 - 82 45 - 83 Child-Pugh-Score, n (%) 0.892 A 76 (65.0) 30 (63.8) B 41 (35.0) 17 (36.2) BCLC, n (%) 0.412 A 68 (58.1) 24 (51.1) B 49 (41.9) 23 (48.9) Tumor size, mm (mean +- SD) 22 +- 9 20 +- 8 0

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