Search Results

91 - 100 of 358 items :

  • pharmacokinetics x
Clear All
Drug Methods for Arteficial Termination of Unwanted Pregnancy

of Clinical Endocrinology & Metabolism 60.1 (1985): 156-163. 4. Kekkonen, Raimo, et al. “Pharmacokinetics of mifepristone after low oral doses.” Contraception 54.4 (1996): 229-234. 5. Peyron, Remi, et al. “Early termination of pregnancy with mifepristone (RU 486) and the orally active prostaglandin misoprostol.” New England Journal of Medicine 328.21 (1993): 1509-1513. 6. Ledger, W. L., et al. “Inhibition of ovulation by low-dose mifepristone (RU 486).” Human Reproduction 7.7 (1992): 945-950. 7. Batista, Marcelo C., et al. “Delayed

Open access
Pixantrone, a new anticancer drug with the same old cardiac problems? An in vitro study with differentiated and non-differentiated H9c2 cells

toxicity: the cardiac susceptibility to oxidative stress. Chem Res Toxicol 26 : 1285–1311. Costa VM, Silva R, Tavares LC, Vitorino R, Amado F, Carvalho F, Bastos ML, Carvalho M, Carvalho RA, Remiao F. (2009). Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes. Toxicology 260 : 84–96. Dawson LK, Jodrell DI, Bowman A, Rye R, Byrne B, Bernareggi A, Camboni G, Smyth JF. (2000). A clinical phase I and pharmacokinetic study of BBR 2778, a novel anthracenedione analogue

Open access
Effect of stilbene derivative on superoxide generation and enzyme release from human neutrophils in vitro

-90. Perečko T, Drabikova K, Nosaľ R, Harmatha J, Bauerova K, Mihalova D, Jančinova V. (2010 a). Inhibition of oxidant production in rat adjuvant arthritis with pterostilbene. Interdiscip Toxicol 3: A73-74. Remsberg CM,Yanez JA, Ohgami Y,Vega-Villa KR, Rimando AM, Davies NM. (2008). Pharmacometrics of pterostilbene. Preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity. Phytother Res 22 : 169-179. Rimando AM, Cuendet M, Desmarchelier C, Mehta RG, Pezzuto JM, Duke SO. (2002). Cancer

Open access
Photochemical toxicity of drugs intended for ocular use

. Chromatographia 2009;69(Supplement):115-22. doi: 10.1365/s10337-009-1082-3 21. Epaulard O, Saint-Raymond C, Villier C, Charles J, Roch N, Beani JC, Leccia MT. Multiple aggressive squamous cell carcinomas associated with prolonged voriconazole therapy in four immunocompromised patients. Clin Microbiol Infect 2010;16:1362-4. doi: 10.1111/j.1469-0691.2009.03124.x 22. Scholz I, Oberwittler H, Riedel KD, Burhenne J, Weiss J, Haefeli WE, Mikus G. Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation

Open access
Effects of Progesterone on Benzene Toxicity in Rats

1991;755-762. Porter TD, Coon MJ Cytochrome P450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. J Biol Chem 1991;266:13469-72. Kato R, Kamataki T Cytochrome P450 as a determinant of sex difference of drug metabolism in the rat. Xenobiotica 1982;12:787-800. Harris RZ, Benet LZ, Schwartz JB Gender effects in pharmacokinetics and pharmacodynamics. Drugs 1995;50:222-39. Luis FOH, Adolfo SS, Mariano EC, Manno M, Albores A

Open access
Can a Person with Attention Deficit Hyperactivity Disorder be an Athlete?

-Deficit Hyperactivity Disorder in Athletes, Curr Sports Med Rep. 2011;10(1):32-36. 23. Comiran E, Kessler FH, Fröehlich PE et al - Lisdexamfetamine: A pharmacokinetic review, Eur J Pharm Sci. 2016;89:172–179. 24. Garnock-Jones KP, Keating GM - Atomoxetine: a review of its use in attention-deficit hyperactivity disorder in children and adolescents, Pediatr Drugs. 2009;11(3):203-226. 25. Strange BC– Once-daily treatment of ADHD with guanfacine: patient implications. Neuro psychiatr Dis Treat. 2008;4(3):499-506. 26. Söderlund GBW, Björk C, and Gustafsson P

Open access
Fifty-Five years of Pediatric Endocrinology and 50 years of the Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases in Slovenia / 55 Let Pediatrične Endokrinologije in 50 Let Kliničnega Oddelka Za Endokrinologijo, Diabetes in Presnovne Bolezni Pediatrične Klinike

-acting pegylated human GH in children with GH deficiency: a single-dose, dose-escalation trial investigating safety, tolerability, pharmacokinetics and pharmacodynamics. Eur J Endocrinol 2011; 165: 401-9. 5. Raivio T, Avbelj M, McCabe MJ, Romero CJ, Dwyer AA, Tommiska J. et al. Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia. J Clin Endocrinol Metab 2012; 97: E694-9. 6. Kotnik P, Keuper M, Wabitsch M, Fischer-Posovszky P. Interleukin-1β downregulates RBP4 secretion in human adipocytes. PLoS

Open access
Evaluation of Teratogenic Activity of Antiepileptic Drug Lamotrigine in Mouse Fetuses

, Bastaki S, et al. Experimental studies on reproductive toxicologic effects of lamotrigine in mice. Birth Defects Res B Dev Reprod Toxicol 2003; 68(5): 428-38. 30. Ohman I, Vitols S, Tomson T. Lamotrigine in pregnancy: pharmacokinetics during delivery, in the neonate, and during lactation. Epilepsia 2000; 41(6): 709-13. 31. Tunbridge EM, Attenburrow MJ, Gardiner A, et al. Biochemical and genetic predictors and correlates of response to lamotrigine and folic acid in bipolar depression: Analysis of the CEQUEL clinical trial. Bipolar Disorders 2017; 19(6): 477

Open access
Cholinesterases: Structure, Role, and Inhibition

blood cholinesterases by the Ellman method. Arh Hig Rada Toksikol 2000;51:13-8. Thiermann H, Mast U, Klimmek R, Eyer P, Hibler A, Pfab R, Flegenhauer N, Zilker T. Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients. Hum Exp Toxicol 1997;16:473-80. Velan B, Kronman C, Ordentlich A, Flashner Y, Leitner M, Cohen S, Shafferman A. N-glycosylation of human acetylcholinesterase: effects on activity, stability and biosynthesis. Biochem J 1993

Open access
Evaluation of Oxime K203 as Antidote in Tabun Poisoning

colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1960;7:88-95. Thiermann H, Mast U, Klimmek R, Eyer P, Hibler A, Pfab R, Flegenhauer N, Zilker T. Cholinesterase status, pharmacokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients. Hum Exp Toxicol 1997;16:473-80. Eddleston M, Szinicz L, Eyer P, Buckley N. Oximes in acute organophosphorus pesticide poisoning: a systemic review of clinical trials. Qjm-Mon J Assoc Phys 2002

Open access