Yeltay Rakhmanov, Paolo Enrico Maltese, Stefano Paolacci, Carla Marinelli and Matteo Bertelli
sclerosing glomerulopathy), diabetesmellitus ( 2 ), varicose veins, cleft palate, extradural cysts, congenital heart defects (tetralogy of Fallot, ventricular septal defects), ocular findings, such as photophobia, exotropia, droopy eyelids (ptosis), ectropion and cataracts ( 3 , 4 ).
The estimated prevalence of LD is currently unknown.
The clinical diagnosis of LD is based on: primary lymphedema (chronic swelling of the extremities caused by intrinsic dysfunction of the lymphatic vessels); distichiasis (aberrant and/or extra row of eyelashes originating from the
Antonio Malvasi, Andrea Tinelli, Domenico Baldini, Rossana G. Iannitti and Bernard Fioretti
, neural tube closure and the prevention of neural tube defects Birth Defects Res 2017 Jan 30 109 2 68 80
7 Farren M, Daly N. The Prevention of Gestational DiabetesMellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017 Jun;40(6):759-763. 28325784 10.2337/dc16-2449
Farren M Daly N The Prevention of Gestational DiabetesMellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial Diabetes Care 2017 40 6 759 763
8 Brown J, Crawford TJ. Dietary supplementation with myo
Samuel O. Onoja, Glory C. Onyebuchi, Ifeoma I. Ijeh and Maxwell I. Ezeja
practice with suspected anti-inflammatory activity ( 7 ).
Helianthus annuus Linn. belong to the family Asteraceae. It has wide folkloric uses in the ethnomedical practice of South Eastern Nigeria, India and Pakistan ( 8 ). The plant is used in the treatment of pyrexia, inflammation, worm infestation, diabetesmellitus and other stomach problems ( 9 ). The phytochemical screening of the leaf have reported the presences of alkaloids, saponins, glycosides, terpenes, sterols, tannins and flavonoids ( 10 , 11 ). Bioactive compounds such as Helivypolide G, annuionones a, b
Peter M. Eze, Joy C. Nnanna, Ugochukwu Okezie, Happiness S. Buzugbe, Chika C. Abba, Chidimma R. Chukwunwejim, Festus B. C. Okoye and Charles O. Esimone
plants in the search for biologically active molecules.
Newbouldia laevis (Bignoniaceae), Ocimum gratissimum (Lamiaceae), and Carica papaya (Caricaceae) are medicinal plants commonly found in Nigeria. These plants have been used ethnomedicinally in the treatment of several disease conditions including ulcers, burns, diarrhea, bleeding, haemorrhoids, dysentery, abdominal pains, cough, colds, pruritus, stress, headache, pneumonia, conjunctivitis, diabetesmellitus, epilepsy and convulsions ( 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ).