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Ketogenic Diet and Skeletal Muscle Hypertrophy: a Frenemy Relationship?

.1016/S0092-8674(00)80595-4 Brunet A Bonni A Zigmond MJ Lin MZ Juo P Hu LS Anderson MJ Arden KC Blenis J Greenberg ME Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor Cell 1999 96 857 868 Bueno NB, de Melo IS, de Oliveira SL, da Rocha Ataide T. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. Br J Nutr , 2013; 110: 1178-1187 23651522 10.1017/S0007114513000548 Bueno NB de Melo IS de

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Mechanism of Action and the Effect of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation on Different Types of Physical Performance - A Systematic Review

study in human myoblast satellite cells, an increase in the expression of the MyoD protein, one of the markers indicating proliferation of muscle cells, was observed ( Kornasio et al., 2009 ). The same study also noted an increase in the number of cells following the rise of the others myogenic regulatory factors (MRFs, myogenin and MEF2) that are responsible for the differentiation of satellite cells, thus suggesting a direct effect of HMB on myoblast proliferation and differentiation ( Kornasio et al., 2009 ). A similar trend, i.e. an increase in the number of

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Management of immune-related adverse events in patients treated with immune checkpoint inhibitors– Rheumatology point of view

1 Introduction The immune checkpoints, such as cytotoxic T-lymphocyte-associated antigen 4, programmed cell death protein and programmed cell death protein ligand 1, were the normal self-regulatory pathways to control T-cell activities in human body. In tumor microenvironment, these molecules were overexpressed to inhibit the normal T-cell function and survival, leading to an escape from the destruction from immune system. The immune checkpoint inhibitors (ICPis) block this mechanism and restore the T-cell immunity to achieve tumor destructions. However, the

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Mesenchymal Stem Cell Therapy for rheumatic diseases

regulatory T cells in peripheral blood. Further studies will be needed for any conclusive evidence for the application of MSCT in patients with RA. Another potential reason for conflicting results in MSCT studies in RA is that the effective mode of administration of MSCs is still unknown. A comparative study of MSCs showed that intra-articular MSCs were superior in cartilage formation compared with other modes of administration ( 22 ). In previous studies, intraarticular administration of MSCs had a low efficacy in patients with RA ( 23 ). A new delivery method of MSCs

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Changes of standard physiological-perceptual markers and circulating MicroRNAs in response to tennis match-play: A case report of two elite players

different blood samples used ( Wehmeier and Hilberg, 2014 ). While we analyzed capillary whole blood, venous blood serum had been examined in a previous study ( Aoi et al., 2013 ). In contrast to blood serum, capillary blood still contains cells, which may contribute to the differences in observed C T values ( Wehmeier and Hilberg, 2014 ). Since all C T values of this study were below the cut-off value of 35 PCR cycles, where circulating miRs are difficult to quantify ( Aoi et al., 2013 ), our results are appropriate and allow further discussions. Our first major

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The Role of Adrenomedullin in Cardiovascular Response to Exercise – A Review

nitroprusside: interactions with ANG II and norepinephrine Am J Physiol Regul Integr Comp Physiol 2001 281 R1887 1894 Chini EN, Choi E, Grande JP, Burnett JC, Dousa TP. Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway. Biochem Biophys Res Commun , 1995; 215: 868-873 10.1006/bbrc.1995.2544 Chini EN Choi E Grande JP Burnett JC Dousa TP Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway Biochem Biophys Res Commun 1995 215 868 873 Cockcroft JR, Noon JP, Gardner-Medwin J, Bennett T. Haemodynamic effects of

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The GABPB1 gene A/G polymorphism in Polish rowers

:63,269-273. Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP, Holloszy JO. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 2002:16,1879-1886. Bouchard C, Rankinen T, Chagnon YC, Rice T, Perusse L, Gagnon J, Borecki I, An P, Leon AS, Skinner JS, Wilmore JH, Province M, Rao DC. Genomic scan for maximal oxygen uptake and its response to training in the HERITAGE Family Study. J Appl Physiol. 2000:88,551-559. Druzhevskaya AM, Ahmetov II, Astratenkova IV

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Complementary and alternative medicine for rheumatic diseases

groups. The tender joint count significantly reduced for the EA and TCA groups. The physician’s global score was significantly reduced for the EA group, and the patient’s global score was significantly reduced for the TCA group. [ 4 ] Systemic lupus erythematosus In Systemic lupus erythematosus (SLE), several diet supplements were investigated for their efficacy, as shown in table 1 . Table 1 Proposed mechanism Results Vitamin D supplement Increase regulatory T cells and decrease Th17, Th1 and memory B cells. Lower levels

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Impact of the Polymorphism Near MC4R (rs17782313) on Obesity- and Metabolic-Related Traits in Women Participating in an Aerobic Training Program

Langenberg C Aadahl M Grarup N Linneberg A Paré G. Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry PLoS Genet 2013 9 7 e1003607 Balthasar N, Dalgaard LT, Lee CE, Yu J, Funahashi H, Williams T, Ferreira M, Tang V, McGovern RA, Kenny CD, Christiansen LM, Edelstein E, Choi B, Boss O, Aschkenasi C, Zhang CY, Mountjoy K, Kishi T, Elmquist JK, Lowell BB. Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell , 2005; 123(3): 493-505 10.1016/j.cell.2005

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Contribution of Peripheral and Central Fatigue in Different Conditions (Gender and Time of Day Differences)

menstrual cycle and sport performance. Clin Sports Med. 2005. 24:51-82. Chen XY, Chen L, Wolpaw JR and Jakman LB. Corticospinal tract transaction reduces H-reflex circadian rhythm in rats. Brain research, 2002. 942(1-2): p101-108. Darleen A, Sandoval S, Katheleen S. Gender differences in the endocrine and metabolic responses to hypoxic exercise. Appl Physiol 2002. 92: 504-512. Davis, SN, Galassett P, Wasserman DH, and Tate D. Effects of gender on neuroendocrine and metabolic counter regulatory

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