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  • Author: Wei Ming x
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Open access

Joe-Ming Yang, Zen-Wei Yang and Chien-Ming Tseng

ABSTRACT

In this study, numerical analysis was carried out by using the finite element method to construct the first mode shape of damaged stiffened plates, and the damage locations were detected with two-dimensional discrete wavelet analysis. In the experimental analysis, four different damaged stiffened structures were observed. Firstly, each damaged structure was hit with a shaker, and then accelerometers were used to measure the vibration responses. Secondly, the first mode shape of each structure was obtained by using the wavelet packet, and the location of cracks were also determined by two-dimensional discrete wavelet analysis. The results of the numerical analysis and experimental investigation reveal that the proposed method is applicable to detect single crack or multi-cracks of a stiffened structure. The experimental results also show that fewer measurement points are required with the proposed technique in comparison to those presented in previous studies.

Open access

Wei-Hsien Hou, Chun-Wei Wang, Chiao-Ling Tsai, Feng-Ming Hsu and Jason Chia-Hsien Cheng

Abstract

Background

Changes in head and neck anatomy during radiation therapy (RT) produce setup uncertainties of nasopharyngeal cancer (NPC) irradiation. We retrospectively analyzed image guidance data to identify clinical predictors of setup errors.

Patients and methods

The data of 217 NPC patients undergoing definitive RT on a helical tomotherapy (HT) unit were analyzed. Factors including tumor stage, body mass index, weight loss, and planning target volume (PTV) were assessed as predictors of daily megavoltage computed tomography (MVCT) setup displacements, which were automatically registered using software.

Results

Mean daily setup displacements (in mm) were 1.2 ± 0.6, 1.8 ± 0.8, 3.4 ± 1.4 in the medial-lateral (ML), superior-inferior (SI), and anterior-posterior (AP) directions, respectively. Mean weight loss was 4.6 ± 3.3 kg (6.8 ± 4.9%). Patients with weight loss > 5% had significantly larger setup displacements in the AP (3.6 ± 1.5 vs. 2.9 ± 1.1 mm, p < 0.001) and SI (1.6 ± 0.7 vs. 1.9 ± 0.9 mm, p = 0.01) direction, but not in the ML direction (p = 0.279). The AP setup error increased 0.06 mm (y = 0.055x + 2.927, x: percentage of weight loss/PTV, y: AP displacement) per one percent increase in weight loss normalized to PTV.

Conclusions

Patients with weight loss > 5% and smaller PTVs, possibly because of small body frame or neck girth, were more likely to have increased setup errors in the AP direction.

Open access

Jing Zhang, Shu-Ming Zhou, Li Xu, Wei Wu and Xiucai Ye

Abstract

The connected dominating set (CDS) has become a well-known approach for constructing a virtual backbone in wireless sensor networks. Then traffic can forwarded by the virtual backbone and other nodes turn off their radios to save energy. Furthermore, a smaller CDS incurs fewer interference problems. However, constructing a minimum CDS is an NP-hard problem, and thus most researchers concentrate on how to derive approximate algorithms. In this paper, a novel algorithm based on the induced tree of the crossed cube (ITCC) is presented. The ITCC is to find a maximal independent set (MIS), which is based on building an induced tree of the crossed cube network, and then to connect the MIS nodes to form a CDS. The priority of an induced tree is determined according to a new parameter, the degree of the node in the square of a graph. This paper presents the proof that the ITCC generates a CDS with a lower approximation ratio. Furthermore, it is proved that the cardinality of the induced trees is a Fibonacci sequence, and an upper bound to the number of the dominating set is established. The simulations show that the algorithm provides the smallest CDS size compared with some other traditional algorithms.

Open access

Ya-Ya Guan, Mian Li, Xiao-Ou Chen, Wei Yang, Ming-Ming Tang, Yu-Hong Chen and Yin-Fei Zhang

Abstract

Objective: The objective of the following study is to investigate the relationship between blood lipid levels and carotid intima-media thickness (CIMT) in Shanghai urban population. Materials and Methods: A total of 2504 residents over 40 years old in Jiading District of Shanghai municipality were divided into two groups in terms of the CIMT value 0.7 mm: Thickened group (n = 478) and normal group (n = 2026). All the patients received examinations of height, weight, waist, blood pressure, blood lipid level, hepatic and renal function, oral glucose tolerance test and carotid artery B-ultrasonography. Results: In comparison with those in CIMT normal group, the proportion of males, ages, body mass index, systolic blood pressure and levels of fast blood glucose, total cholesterol (TC), triglyceride (TG) and lowdensity lipoprotein cholesterol (LDL-C) were increased, but the levels of fast insulin were decreased (all P < 0.05). The risks of CIMT thickness were elevated by 19% and 25% as every increase in the standard deviation of the TC and LDL-C levels respectively (95% of confidence interval [CI] 1.08-1.31; 95% CI 1.13-1.37). Statistical analysis showed a significant correlation between CIMT thickness and TC/LDL-C. The levels of TG and high-density lipoprotein cholesterol were not associated with CIMT thickness. Conclusions: Levels of blood TC and LDL-C have significant correlations with the CIMT thickness in Shanghai urban population.

Open access

Jing-Yi Cheng, Yi-Dong Zhang, Liang Cheng, Ming Ji, Wei Gu and Lin-Sheng Gao

Abstract

According to complex geological conditions of working face E1108 in Xin-ji mine #2, loading and running characteristic of hydraulic support, influence of depression angle on mining pressure behaviors, as well as relation between advancing speed and the support loading were measured and analyzed. The results indicate that depression angle is inversely proportional to support resistance, in other words, larger depression angle area coincides with lower support resistance area. Moreover, support resistance is generally high when working face advancing speed is slow. Technologies for controlling hydraulic support stability such as improving advancing speed properly, controlling mining height and increasing support resistance are put forward based on research.

Open access

Likai Zhuang, Ming Bai, Wei Zhou, Yongguo Yu, Jian Wang, Qihua Fu and Jie Sun

Summary

Background: This study aimed to investigate the significance of MAMLD1 mutations in the incidence of hypospa-dias in a Chinese population.

Methods: The experimental group consisted of 150 domestic children with hypospadias, aged 0.5 to six years and living in different provinces. A total of 120 normal children, aged two to six years, served as the control group. DNA was extracted for the direct sequencing of MAMLD1 genes.

Results: Twelve cases (8.0%) of the missense mutation p.N589S were found in the experimental group, whereas four cases (3.0%) of the same mutation were found in the control group. No significant difference was observed in the mutation rate between the two groups (P>0.05). Four cases (2.7%) had a new missense mutation p.P567S in the experimental group, and three cases (2.5%) possessed the same mutation in the control group. No significant difference was observed between the two groups (P>0.05).

Conclusions: In this study, the importance of repeated experiments in mutation-related studies was confirmed, which revealed the difference in predisposing genes among different populations. Although the mutation of the MAMLD1 gene had no apparent connection with the incidence of hypospadias in a Chinese population, a new mutation site of the MAMLD1 gene was discovered, which could provide new research topics for future studies.

Open access

Gui-lin Yang, Ying-xia Liu, Mu-tong Fang, Wei-long Liu, Xin-chun Chen, John Nunnari, Jing-jing Xie, Ming-feng Liao, Ming-xia Zhang, Guo-bao Li, Pei-ze Zhang, Yi Guan and Boping Zhou

Abstract

Objective To explore whether age, disease severity, cytokines and lymphocytes in H1N1 influenza A patients correlate with viral load and clearance.

Methods Total of 70 mild and 16 severe patients infected with H1N1 influenza A virus were enrolled in this study.

Results It was found that the patients under 14 years old and severe patients displayed significantly higher viral loads and prolonged viral shedding periods compared with the patients over 14 years old and mild patients, respectively (P < 0.05). Moreover, the patients under 14 years old and severe patients displayed significantly lower Th17 cell frequency than the patients over 14 years old and mild patients (P < 0.01). The viral shedding period inversely correlated with the frequency of IL-17+IFN-γ-CD4+ T cells. Additionally, the decreased concentration of serum TGF-β correlated with the decreased frequency of IL-17+IFN-γ-CD4+ T cells.

Conclusions Both younger and severe patients are associated with higher viral loads and longer viral shedding periods, which may partially be attributed to the impaired Th17 cell response.