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Tiberius Mogoș, Carmen Dondoi and Andra Evelin Iacobini

Abstract

Oxalosis is an inborn error of metabolism, with autosomal recessive transmission, defined by an excessive endogenous production of oxalic acid, with secondary deposits in different tissues (eyes, bones, muscles, blood vessels, heart and other organs) and a high renal excretion. Hyperoxaluria is rare, though it can be identified in about 20 % of individuals with kidney stones. Its quick diagnosis and treatment are essential to the long-term health of kidneys. The aim of this article was to make a review of the literature regarding this potentially lethal condition.

Open access

Tiberius Mogoş, Carmen Dondoi and Andra Evelin Iacobini

Abstract

Dietary fibers are a type of carbohydrates that are found in plant-based foods. They are not absorbed or digested by the body, but play an important role in maintaining good health. There are two types of dietary fiber - soluble and insoluble. Most foods contain both types, but are usually richer in one type than the other. Current evidence suggests that high-fiber diets, especially of the soluble variety, may offer some improvement in weight management, in carbohydrate metabolism, lower total and LDL cholesterol, and have other positive effects in patients diagnosed with diabetes (improvement of insulin sensitivity, modulation of the secretion of certain gut hormones, improvement of various metabolic and inflammatory markers associated with the metabolic syndrome), thus reducing the risk of cardio-metabolic diseases. The aim of our review is to reinforce the role of dietary fiber in the improvement of diabetes management

Open access

Tiberius Mogoş and Andra Evelin Iacobini

Abstract

Fructose intolerance is a metabolic disorder with hereditary determinism, clinically manifested on terms of fructose intake. Untreated, hereditary fructose intolerance may result in renal and hepatic failure. Unfortunately, there are no formal diagnostic and surveillance guidelines for this disease. If identified and treated before the occurrence of permanent organ damage, patients can improve their symptoms and self-rated health. Implementation and adherence to a strict fructose free diet is often difficult, but not impossible.

Open access

Tiberius Mogoş, Carmen Dondoi, Claudia-Valeria Chelan, Andra Iacobini and Mihaela Buzea

Abstract

Background and aims: Insulin resistance (IR) is a common pathogenic factor of several diseases: diabetes mellitus, the metabolic syndrome, arterial hypertension, atherosclerosis, dyslipidemia, etc. There are many therapeutic factors involved in decreasing IR. Among them we mention metformin, pioglitazone, physical activity, weight loss, diet, etc. In the last decade, there are more observations of the influence of polyunsaturated fatty acids on IR. The most powerful seem to be omega-3 fatty acids. In our study, we wanted to asses if the administration of omega-3 fatty acids is involved in modifying IR. Materials and methods: We evaluated 126 diabetic patients with IR from January 2011 until July 2014. The study was open-label and non-randomized. For the determination of IR we used the HOMA-IR method. Results: For both males and females there was a regression of HOMA-IR during the 4 weeks of treatment with omega-3 and also after 2 weeks after stopping the administration of these fatty acids. The decrease of HOMA-IR was statistically significant (p<0.05). The statistic result observed in the next 2 weeks after stopping administration of omega-3 was also significant (p<0.05).

Conclusion: The results of the study showed that the omega-3 fatty acids can reduce IR. The greater the IR, the smaller the results for the same dose of omega-3. The effect of these fatty acids on IR continues after the end of treatment.

Open access

Tiberius Mogoş, Carmen Dondoi, Claudia Chelan and Andra Evelin Iacobini

Abstract

Both the medical practice and the scientific research proved that a number of nutritional products or nutritive elements could have a preventive role (especially in subjects in whom these reach a lower level than the physiological ones) in the prevention of cancer. The list of these products is quite large, but in this article we shall present only part of them. We emphasize that the aliments described are easy to find and are not expensive.

Open access

Tiberius Viorel Mogos, Claudia Valeria Chelan, Carmen Ionela Dondoi, Andra Evelin Iacobini and Mihaela Buzea

Abstract

Background and Aims: Ileostomy induces important local and general complications. The present study evaluates if nutrition therapy can influence the development of these complications. Methods: We evaluated a group of 43 patients with ileostomy, without general complications after the surgical intervention, starting from the second day following surgery, for a period of 8 weeks. The mean age was 58.2 ±8.7 years and body mass index (BMI) of 28.2 ±6.5 kg/m2. The patients were divided into 2 groups: one following a diet prescribed by a nutrition specialist (group 1), and another with scarce notions of nutrition given by the attending surgeon (group 2). Results: When comparing group 1 with group 2, we observed: obstruction of the ileostomy in 1% vs. 49% (p<0.01); skin abrasions around the ileostomy in 21% vs. 97% (p<0.01); unpleasant odors at the site of the stoma in 16% vs. 99% (p<0.01); mean BMI 26.2 ± 4.3 kg/m2 vs. 19.4 ± 3.3 kg/m2 (p<0.01); natremia 138.1 ± 2.1 mEq/l vs. 129.2 ± 3.3 mEq/l (p<0.01); kalemia 4.2 ± 0.2 mEq/l vs. 3.1 ± 0.3 mEq/l (p<0.01). Conclusion: A correct nutrition of patients with ileostomy reduces the rate of local and general complications related to surgical procedures.