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Open access

Stefan Sacchi and Thomas Meyer


Am Übergang in nachobligatorische Ausbildungsgänge durchlaufen viele Jugendliche in der Schweiz eine sogenannte Übergangslösung oder ein Brückenangebot wie z. B. ein zehntes Schuljahr. Wir beleuchten in diesem Beitrag zum einen, wie schulische, individuelle, familiäre und systemische Kontextfaktoren den Übertritt in solche Brückenangebote beeinflussen. Zum anderen gehen wir der Frage nach, wie sich ein verzögerter Einstieg über ein Brückenangebot auf die Chance auswirkt, eine Ausbildung auf Sekundarstufe II zu beginnen bzw. abzuschliessen. Auf der Basis der TREE-Daten modellieren wir zunächst die interessierenden Übertrittsprozesse mittels einer multinomialen logistischen Regression, um dann mittels Propensity Score Matching deren Wirkung auf die nachobligatorischen Bildungschancen abzuschätzen.

Open access

André Berchtold, Joan-Carles Surís, Thomas Meyer and Zhivko Taushanov


In this study we explored the development of somatic complaints among adolescents and young adults aged 16 to 30 years in Switzerland. Using data from the Transitions from Education to Employment (TREE) study, we applied a hidden Markovian model with covariates to cluster trajectories representing the sum of eight somatic complaints. The resulting groups differed mainly in terms of gender, reading literacy, and substance use. The trajectories of somatic complaints were also related to the number of critical events experienced by the respondents.

Open access

Stefan Meyer, Karsten Wesche, Christoph Leuschner, Thomas van Elsen and Jürgen Metzner

A new conservation strategy for arable plant vegetation in Germany-the project "100 fields for biodiversity"

It is prudent to conserve communities which are as species-rich as possible. This is the only means of ensuring that species diversity but also gene diversity is high enough to allow for the necessary adaptations to changed environmental conditions. Arable plant communities are a special case here because losses in the last 5 decades have been particularly severe. Numerous studies from Central Europe reported dramatic declines of the segetal flora.

In most of the federal states of Germany, successful measures for protecting the segetal flora, such as the establishment of field flora reserves and field margin strip programmes have often unfortunately come to a halt due to changes in funding, lack of regional support or high levels of bureaucracy. The new project "100 fields for biodiversity", which has been funded by the Deutsche Bundesstiftung Umwelt (DBU) since 2007, aims to establish a network of protected areas for the preservation of endangered segetal species in Germany. Management aimed at preserving and fostering arable wild plants is to be guaranteed in the long term on at least 100 particularly suitable arable sites.

The feasibility study, funded by the DBU during 2007-2008 undertook: 1)Identification of floristically valuable arable sites throughout Germany and their incorporation in a database; 2)Compilation of an overview of field flora reserves/conservation fields still in existence based on a countrywide search; 3)Discussions about funding instruments and the options for implementing protection measures at a regional level with governmental authorities of all the federal states of Germany (excluding Hamburg, Bremen and Berlin); 4)Analysis of several alternative strategies for long-term financing of arable plant conservation.

The project "100 fields for biodiversity - establishing a nationwide conservation field network for wild arable plants" - is a national endeavour to provide a network of conservation sites as a long-term response to the loss of arable wild plants which has advanced unabated for decades. As a first milestone in the implementation phase it is aimed at securing 30 sites during the first two years of the project. By the end of the entire funding period there should be a network of at least 100 conservation fields under long-term protection. This is a unique opportunity in the history of the protection of arable wild plants of creating an urgently needed conservation system with at least medium-term protection for native arable wild plants.

Open access

Ingo Gastinger, Frank Meyer, Thomas Lembcke, Uwe Schmidt, Henry Ptok and Hans Lippert

Impact of Fast-Track Concept Elements in the Classical Pancreatic Head Resection (Kausch-Whipple Procedure)

The aim of the study was to determine statistically significant factors with an impact on the early postoperative surgical outcome.

Material and methods. The influence of applied fast-track components on surgical results and early postoperative outcome in 143 consecutive Kausch-Whipple procedure patients was evaluated in a single-center retrospective analysis of a prospective collection of patient-associated pre-, peri- and postoperative data from 1997-2006.

Results. The in-hospital mortality rate was 2.8% (n=4). Fast-track measures were shown to have no effect on the morbidity rate in the multi-variate analysis. Over the study period, a decrease of intraoperative infusion volume from 14.2 mL/kg body weight/h in the first year to 10.7 mL/kg body weight/h in the last year was accompanied by an increase in patients requiring intraoperative catecholamines, up from 17% to 95%. The administration of ropivacain/sufentanil via thoracic peri-dural catheter injection initiated in 2000 and now considered the leading analgesic method, was used in 95% of the cases in 2006. Early extubation rate rose from 16.6% to 57.9%.

Conclusions. Fast-track aspects in the perioperative management have become more important in several surgical procedure even in those with a greater invasiveness such as Kausch-Whipple. However, such techniques used in peri-operative management of Kausch-Whipple pancreatic-head resections had no impact on the morbidity rate. In addition, the low in-hospital mortality rate was particularly attributed to surgical competence.

Open access

Frank Meyer, Thomas Buerger, Zuhir Halloul, Hans Lippert, Brigitte König and Joerg Tautenhahn


The aim of the study was to investigate the immune-modulatory potential of commercially available PTFE and polyester vascular grafts with and without gelatine-coating. The biomaterial-cell-interaction was characterized by changes of established parameters such as PMN-related receptors/mediators, phagocytosis potential and capacity as well as the effect of an additional plasma-dependent modulation.

Material and methods. By means of a standardized experimental in vitro model, various vascular graft material (PTFE/polyester/uncoated/gelatine-coated) was used for incubation with or without plasma and co-culturing with human neutrophile granulocytes (PMN) followed by analysis of representative receptors and mediators (CD62L, CD11b, CXCR2, fMLP-R, IL-8, Elastase, LTB4). Oxidative burst assessed phagocytosis capacity.

Results. Comparing the vascular grafts, un-coated PTFE induced the lowest magnitude of cell stimulation whereas in case of gelatine-coating, cell response exceeded those of the other vascular grafts. This was also found comparing the polyester-based prosthetic material. Gelatine-coated polyester led to a more pronounced release of elastase than gelatine-coated PTFE and the uncoated materials. The results of oxidative burst indicated a reduced phagocytosis capacity in case of gelatine-coated polyester. Plasma incubation did also provide an impact on the cellular response. While in case of gelatine-coating, PMN-related receptor stimulation became lower, it increased by native polyester. The latter one did also induce more mediators such as IL-8 and LTB4 than gelatine-coated material.

Conclusions. There have been no extensive data on cell-cell interactions, cytokines and general histo-/hemocompatibility of human cells by the new generation of vascular grafts. It remains still open whether healing process and infectious resistance can be compromised by material-dependent over-stimulation or reduced phagocytosis potential of the immune cells of the primary unspecific immune response induced by gelatine-coated materials.