In a piled-raft foundation, the interaction between structural elements and soil continuum can be simulated very precisely by numerical modeling. In the present study, 3D finite element model has been used to examine the settlement, load-sharing, bending moment, and shear force behavior of piled-raft foundation on different soil profiles for different load configurations and pile-raft configurations (PRCs). The model incorporates the pile-to-soil and raft-to-soil interactions by means of interface elements. The effect of parameters such as pile spacing and raft thickness are also studied. For any soil profile, larger pile spacing is observed to be more efficient in reducing the average settlement and enhancing the load-sharing coefficient. The smaller pile spacing is observed to be efficient in reducing the differential settlement. For any soil profile, the behavior of piled-raft foundation is significantly affected by the PRCs and load configurations. Furthermore, the raft thickness has significant effect on settlement, bending moment, and shears force. Thus, the results of the present study can be used as guidelines for analyzing and designing large piled-raft foundation.