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R. Sharma, P. Samadhiya, S. Srivastava and S. Srivastava

Synthesis of Some New Thiazolidine Derivatives and Their Biological Significance

An efficient route for the synthesis of new series of N-[3-(1H-1,2,3-benzotriazol-1-yl)-propyl]-2-(substituted phenyl)-4-oxo-5-(substituted benzylidene)-1,3-thiazolidine carboxamide, compounds 5 (a-j) has been elaborated. The compounds 5 (a-j) have been synthesized and characterized by IR, 1H NMR, 13C NMR, FAB Mass spectra and chemical analysis. All final compounds were screened for their antimicrobial activity against some selected bacteria, fungi, antituberculosis (against M. tuberculosis) and antiinflammatory activity on albino rats.

Open access

H. M. Srivastava, S. Sivasubramanian and R. Sivakumar

Abstract

Let ∑ denote the class of functions

belonging to the normalized analytic function class A in the open unit disk U, which are bi-univalent in U, that is, both the function f and its inverse f-1 are univalent in U. The usual method for computation of the coefficients of the inverse function f-1(z) by means of the relation f-1(f(z))= z is too difficult to apply in the case of m-fold symmetric analytic functions in U. Here, in our present investigation, we aim at overcoming this difficulty by using a general formula to compute the coefficients of f-1(z) in conjunction with the residue calculus. As an application, we introduce two new subclasses of the bi-univalent function class ∑ in which both f(z) and f-1(z) are m-fold symmetric analytic functions with their derivatives in the class P of analytic functions with positive real part in U. For functions in each of the subclasses introduced in this paper, we obtain the coefficient bounds for |am+1| and |a2m+1j|.

Open access

S. Gupta, N. Banu and A. Srivastava

Abstract

Glutathione metabolism represents a prospective target for antifilarial drug design, and therefore, the alterations in glutathione (GSH) content of filarial worms by known mammalian GSH depletors i.e. dimethylmaleate (DMM) and phorone were first thought for investigation in model filarial worms Setaria cervi. The dose dependent GSH depletion was achieved when these worms were incubated at 37°C for 6 h in Hanks balanced salt solution with varying concentrations (10–250 μM) of DMM or phorone. During the short incubation period of 6 h, 250 μM of DMM and phorone declined more than 90 % of the GSH content of filarial worms.

Open access

H. S. Ginwal, S. S. Phartyal, P. S. Rawat and R. L. Srivastava

Abstract

The aim of the study was to determine source variation in Jatropha curcas seeds collected from ten locations in Central India. A significant seed source variation was observed in seed morphology (colour, size and weight), seed germination (viability, germination percent, germination energy, germination value) and seedling growth parameters (survival percentage, seedling height, collar diameter, leave/plant, and seedling biomass). The seed source of Chhindwara (M.P.) was found as the best source in comparison to others. The phenotypic and genotypic variance, their coefficient of variability and broad sense heritability also showed a sizeable variability. This offers a breeder ample scope to undertake screening and selection of seed sources for the desired traits. Further, high percentage of heritability coupled with moderate intensity of genetic gain, was observed for seed germination traits, which signifies that germination is under strong genetic control and good amount of heritable additive genetic component can be exploited for improvement of this species.

Open access

H. S. Ginwal, P. S. Rawat and R. L. Srivastava

Abstract

Results of a seed source evaluation trial of Jatropha curcas Linn. laid out in 1996 at Jabalpur (M.P), a semi arid region of India are reported and discussed. Seeds collected from ten sources from central India representing the states Madhya Pradesh and Maharashtra viz. Gondia, Bichia, Balaghat, Niwas, Khandwa, Burhanpur, Nasik, Chindwara, Kundam and Jabalpur were evaluated for their growth performance from nursery stage (3 months) to field (two years). Variation in seed oil content of different sources were also studied and reported. Significant differences between the seed sources at age 27 months were observed for height, collar diameter, number of branches leaf area and field survival. Seeds collected from different sources also varied significantly in respect of seed and kernel weight and oil content in seed/kernel. The Chhindwara (M.P.) source performed the best and yielded a maximum oil of 39.12% from whole seed and 58.12% from kernel. The oil content ranged from 33.02 to 39.12% in whole seeds and 47.08 to 58.12% in kernel, across the seed sources. The performance of Kundam (M.P.), Jabalpur (M.P.), Bichia (M.P.), Niwas (M.P.) and Nasik (Maharashtra) sources were also found satisfactory for oil yield. Results indicate that genetic differences exist between the seed sources of J. curcas. The growth traits showed significant positive correlation with each other. Fair differences between phenotypic and genotypic coefficient of variability were observed. Heritability (broad sense) values were fairly good with regard to leaf area, height and collar diameter in comparison to survival percent. The relative performance of these sources was fairly consistent throughout the observation period.

Open access

Ashok K. Srivastava, Pravin S. Ingle, Harihar S. Lunge and Neloy Khare

Abstract

Sediment samples have been collected from the Schirmacher Oasis and adjoining area in East Antarctica; these areas consist of polar ice, ice-free area, lakes and the coastal shelf area. The 37 samples have been analysed for their grain-size parameters and statistical relationships. The oasis is characterised by ongoing glacial processes, including deposition and erosion of the sediments by ice, meltwater and winds, thus influencing the sediments in various ways. Basic statistical grain-size parameters like graphic mean, standard deviation, skewness and kurtosis have been calculated for the four units. The sediments of all areas are almost all poorly to very poorly sorted, fine-skewed to near-symmetrical and platykurtic to leptokurtic in nature. Bivariate plots between the grain-size parameters have been interpreted. They do, apart from a few exceptions, not show any trend suggesting relationships between the sediments of the four landscape types. Both t- and F-tests have been applied on the samples, and the phi values and grain-size parameters have been analysed; these show that the group variances of the samples are not significant, but that the phi-values are significant.

Open access

A.K.L. Srivastava, S.R. Pandey and A. Kumar

The vibration characteristics of stiffened plates with cutouts subjected to in-plane partial edge loadings at one end at the plate boundaries are studied using the finite element method. Buckling loads and vibration frequencies are determined for different cutout ratios and extent of partial edge loading at one end. In the structural modelling, the plate and the stiffeners are treated as separate elements where the compatibility between these two types of elements is maintained. The main elegance of the formulation lies in the treatment of the stiffeners. The stiffeners can be placed anywhere within the plate element, and need not be placed on the nodal lines. The vibration characteristics are discussed and the results are compared with those available in the literature. Numerical results are presented for a range of cutout to plate size from 0 to 0.8.

Open access

Asheesh Kumar Gupta, Aditya Srivastava and R.L.S. Sengar

Abstract

The vertebral column is involved in less than 1% of all the cases of tuberculosis. It can associated with major neurological deficits due to compression of adjacent neural structures with significant deformity of spinal column. Therefore, early diagnosis and management of spinal TB has special importance in preventing these serious complications. In order to extract current trends in diagnosis and medical or surgical treatment of spinal TB we performed a review with patients admitted to our hospital between 2016 and 2017. Although the development of more accurate imaging modalities such as magnetic resonance imaging and advanced surgical techniques have made the early diagnosis and management of spinal TB much easier, these are still very challenging topics. In this review we aim to discuss the diagnosis and management of spinal TB based on studies with acceptable design, clearly explained results and justifiable conclusions.

Open access

Pankaj Kumar Srivastava and Dinesh C. S. Bisht

Abstract

This research article discusses the problems having flexible demand, supply and cost in range referred as interval data based transportation problems and these cannot be solved directly using available methods. The uncertainty associated with these types of problems motivates authors to tackle it by converting interval to fuzzy numbers. This confront of conversion has been achieved by proposing a dichotomic fuzzification approach followed by a unique triangular incenter ranking approach to optimize interval data based transportation problems. A comparison with existing methods is made with the help of numerical illustrations. The algorithm proposed is found prompt in terms of the number of iteration involved and problem formation. This method is practical to handle the transportation problems not having a single valued data, but data in form of a range.

Open access

Julee Srivastava and Neeta Singh

Abstract

Some fixed point convergence properties are proved for compact and demicompact maps acting over closed, bounded and convex subsets of a real Hilbert space. We also show that for a generalized nonexpansive mapping in a uniformly convex Banach space the Ishikawa iterates con- verge to a fixed point. Finally, a convergence type result is established for multivalued contractive mappings acting on closed subsets of a com- plete metric space. These are extensions of results in Ciric, et. al. [7], Panyanak [2] and Agarwal, et. al. [9].