The study was conducted to perform a comparative analysis of the mechanical properties of wood samples derived from oaks in the Krotoszyn Plateau, which depend on the health state of the trees. Strength parameters of oak wood were calculated for selected diseased and healthy trees (according to the Roloff classification). The study was conducted by a modified method described in the standard Polish Norm PN EN 408+ A1: 2012. For testing, prior selection of wood samples showed that more wood samples of diseased trees compared with those of healthy oaks did not fulfil the Polish standard requirements. According to the method used, the average results of strength tests of timber structures from healthy oaks exhibited higher strength parameters than those of the diseased trees.