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Onanong Jitkritsadakul, Priya Jagota and Roongroj Bhidayasiri

Abstract

Tremor is one of the most common and most debilitating symptoms of Parkinson’s disease (PD). Classic pill-rolling resting tremor is characteristic of PD and distinguishes it from other neurodegenerative disorders. Although it represents the most typical and most common form of tremor in PD, other tremor manifestations have also been reported to occur in PD. In this article, we review the current clinical classification of tremor with a focus on different types of parkinsonian tremor based on the consensus statement of the Movement Disorders Society. We also provide an overview of different hypotheses on the central mechanisms of the pathophysiology of parkinsonian tremor, and provide evidence for why peripheral mechanisms may play a role in the modulation of PD tremor.

Open access

Dootchai Chaiwanichsiri, Wuttiganok Wangno, Wasuwat Kitisomprayoonkul and Roongroj Bhidayasiri

Abstract

Background: It has been pointed that cueing techniques may have influence upon gait training in Parkinson’s disease (PD).

Objective: Study the effects of music cue on treadmill training in PD patients.

Subject and methods: A randomized single-blind controlled trial was conducted. Thirty male PD patients, aged 60 to 80 years with Hoehn and Yahr stage 2-3 were allocated into three groups (each 10 patients). Group A: treadmill with music three days and home walking three days/week, Group B: treadmill three days and home walking three days/week, and Group C: home walking six days/week. Each group received four weeks training followed by self-practice for other four weeks. Gait performances at pre-program, fourth, and eighth week were compared.

Results: The results showed that A, B, and C, stride length gained 12%, 5.2%, and 6.7% (p=0.042), walking-speed gained 8.6%, 6.5%, and -2.4%, six-minute walk distance gained 10.2%, 5.4%, and 2.9%, and Timed Up and Go (TUG) gained 14.2%, 12.5%, and 7.6%.

Conclusion: Music cue enhanced gait training in mild to moderate PD patients.