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  • Author: Qiang Shi x
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Open access

Zhengyao He, Qiang Shi and Shaoxuan Wu

Abstract

In underwater unmanned vehicles, complex acoustic transducer arrays are always used to transmitting sound waves to detect and position underwater targets. Two methods of obtaining low-sidelobe transmitting beampatterns for acoustic transmitting arrays of underwater vehicles are investigated. The first method is the boundary element model optimization method which used the boundary element theory together with the optimization method to calculate the driving voltage weighting vector of the array. The second method is the measured receiving array manifold vector optimization method which used the measured receiving array manifold vectors and optimization method to calculate the weighting vector. Both methods can take into account the baffle effect and mutual interactions among elements of complex acoustic arrays. Computer simulation together with experiments are carried out for typical complex arrays. The results agree well and show that the two methods are both able to obtain a lower sidelobe transmitting beampattern than the conventional beamforming method, and the source level for each transmitting beam is maximized in constraint of the maximum driving voltage of array elements being constant. The effect of the second method performs even better than that of the first method, which is more suitable for practical application. The methods are very useful for the improvement of detecting and positioning capability of underwater unmanned vehicles.

Open access

Jun Li, Shi-hong Li, Gui-qiang Wang and Hong Zhao

Abstract

Chronic active Epstein-Barr virus (CAEBV) infection is a systemic Epstein-Barr virus (EBV) positive lymphoprolifetative disease characterized by fever, lymphadenopathy, splenomegaly, unusual pattern of anti- EBV antibodies, and/or increased EBV genomes in affected tissues. Most cases are from Asia. So far, there is hardly any adult case reported from mainland of China. We herein presented a 33-year-old man with fever, facial erythema and rash, lymphadenopathy, lower limbs weakness, splenomegaly and liver lesion. EBV VCA, EA and EBNA were all positive. EBV DNA could be found in serum and PBMC. In situ hybridization of EBV encoded RNA in skin and liver biopsy was positive. Viral load in serum decreased under interferon alpha therapy. To our knowledge, it’s the first adult case reported from mainland of China.

Open access

Yong Han, Bingyi Shi, Ming Cai, Xiaoguang Xu, Liang Xu, Qiang Wang, Wenqiang Zhou and Li Xiao

CD20 Expression in the Transplanted Kidney of Patients with Graft Loss and Transient Allograft Dysfunction

This study aimed to explore the relationship between the infiltration of CD20+ B cells and the survival time of a renal allograft and to investigate the role of infiltrated B cells in the rejection of the renal allograft. A total of 40 patients with renal allograft loss due to refractory rejection and 20 patients with transient renal allograft dysfunction were recruited. Renal biopsy was done and CD20 expression was detected by immunohistochemistry. In addition, the survival time of the renal allograft was also obtained. The relationships between the CD20 expression and the survival time of the renal allograft and graft loss due to rejection were analyzed. The associations of gender, age and clinicopathogical types with the CD20 expression were also investigated. The proportion of patients positive for CD20 in the transplanted kidney was higher in patients receiving nephrectomy of the allograft due to rejection than in those with transient allograft dysfunction. The diffuse infiltration of CD20+ B cells was considered as positive staining. In 40 samples from patients with graft loss, 19 had diffuse infiltration of CD20+ B cells (47.5%). In 19 patients positive for CD20, hyperacute rejection was found in 1 patient, acute rejection in 5 and chronic rejection in 13. Statistical analysis showed the CD20 expression was not associated with the age and gender of donors and recipients, regimen for immunosuppressive treatment, cold/warm ischemia time and secondary transplantation. CD20+ B cell infiltration predicts a poor prognosis of patients with kidney transplantation and is one of the risk factors of graft loss.

Open access

Xiangbo Xu, Zhaohui Bai, Qingchun Zhao, Hongyu Li, Qiang Shi, Jiao Deng, Jingqiao Zhang, Xiaozhong Guo and Xingshun Qi

Abstract

Acute-on-chronic liver failure (ACLF) is a potentially lethal syndrome, which is characterized by an acute deterioration of liver function in patients with chronic liver diseases. The present paper reported that an alcoholic cirrhotic patient with ACLF developed septic shock, hydrothorax, ascites, hepatic encephalopathy, acute kidney injury, and acute upper gastrointestinal bleeding at the same hospitalization and was successfully rescued by pharmacotherapy alone without any invasive intervention.

Open access

Guo-liang Zhang, Jian-bo Ding, Shuang-jie Li, Xi Zhang, Yi Xu, Hua-sheng Yang, Dan Wei, Qin Li, Qing-sheng Shi, Qing-xiong Zhu, Tong Yang, Zi-qiang Zhuo, Yi-mei Tian, Hao-jie Zheng, Liu-ping Tang, Xin-ying Zou, Tao Wen and Xiu-hui Li

Objective To evaluate the efficacy and safety of traditional Chinese medicine (TCM) combined with Western medicine in the treatment of patients with common hand, foot and mouth disease (HFMD) by conducting a prospective, controlled, and randomized trial.

Methods A total of 452 patients with common HFMD were randomly assigned to receive Western medicine alone (n = 220) or combined with TCM (Reduning or Xiyanping injections) (n = 232). The primary outcome was the incidence rate of rash/herpes disappearance within 5 days, while secondary outcomes included the incidence rate for fever, cough, lethargy, agitation, and vomiting clearance within 5 days.

Results The rash/herpes disappearance rate was 45.5% (100/220) in Western medicine therapy group, and 67.2% (156/232) in TCM and Western medicine combined therapy group, with significant difference (P < 0.001). Moreover, TCM remarkably increased the incidence rate of secondary disappearance, which was 56.4% in Western medicine therapy group and 71.4% in TCM and Western medicine combined therapy group (P = 0.001). No drug-related adverse events were observed.

Conclusions It’s suggested that the integrative TCM and Western medicine therapy achieved a better therapeutic efficacy. TCM may become an important complementary therapy on relieving the symptoms of HFMD.