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  • Author: Paweł Kalinowski x
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Paweł Kalinowski, Urszula Bojakowska and Marta Kowalska

Abstract

Introduction. Breast cancer is the most commonly found type of cancer in women. One cancer risk factor related to lifestyle that seems to be particularly worth examining is physical activity. The aims of the study were to analyse the physical activity of women who had been diagnosed with breast cancer for the first time and had undergone surgical treatment as well as to determine how their physical activity patterns changed with respect to the patterns from before the diagnosis.

Material and methods. The research was carried out by means of a diagnostic survey. The instrument used was an original questionnaire designed for the purposes of the study. A total of 200 female breast cancer patients were surveyed between September 2015 and April 2016. The data collected in the study were subjected to statistical analysis.

Results. The study showed that after developing cancer, a considerable percentage of women who were not physically active earlier started to perform regular physical activity. Before being diagnosed with cancer, 58% of the respondents did not spend any time engaging in physical activity or only performed it up to 30 minutes per week, whereas after receiving the diagnosis, more than half of the respondents spent a few hours a week being physically active.

Conclusions. After being diagnosed with breast cancer, the majority of patients led a healthy lifestyle; the women surveyed in the study were more active and spent more time engaging in sports and recreation.

Open access

Paweł Kalinowski, Łukasz Woźniak, Anna Strzelczyk, Piotr Jasinski and Grzegorz Jasinski

Abstract

Electrocatalytic gas sensors belong to the family of electrochemical solid state sensors. Their responses are acquired in the form of I-V plots as a result of application of cyclic voltammetry technique. In order to obtain information about the type of measured gas the multivariate data analysis and pattern classification techniques can be employed. However, there is a lack of information in literature about application of such techniques in case of standalone chemical sensors which are able to recognize more than one volatile compound. In this article we present the results of application of these techniques to the determination from a single electrocatalytic gas sensor of single concentrations of nitrogen dioxide, ammonia, sulfur dioxide and hydrogen sulfide. Two types of classifiers were evaluated, i.e. linear Partial Least Squares Discriminant Analysis (PLS-DA) and nonlinear Support Vector Machine (SVM). The efficiency of using PLS-DA and SVM methods are shown on both the raw voltammetric sensor responses and pre-processed responses using normalization and auto-scaling

Open access

Paweł Kalinowski, Elwira Sliwinska and Jerzy Kruk

Abstract

To investigate present and historical distribution of Equisetum ×moorei in Poland and its habitat requirements, field studies at sites of potential occurrence of this hybrid taxon as well as literature and herbarium search were performed. As a results of these investigations, E. ×moorei was found at five contemporary and at a few historical localities in the present territory of Poland. Since the Equisetum populations near Olkusz (S Poland) showed phenotype similar, to some extent, to triploid hybrid E. ×ascendens, we performed nuclear DNA content analysis of these populations. However, it turned out that the investigated individuals belonged to a diploid taxon that can be ascribed to E. ×moorei.

Open access

Artur Pliszko, Grzegorz Łazarski, Paweł Kalinowski, Wojciech Adamowski, Lucjan Rutkowski and Radosław Puchałka

Abstract

In this paper, an updated map of the distribution of Solidago ×niederederi, a natural hybrid between S. canadensis and S. virgaurea, in Poland is presented using the ATPOL cartogram method. A compiled list of 55 localities of the hybrid within 40 cartogram units (10-km squares) is provided and its negative impact on S. virgaurea is highlighted.

Open access

Marek Krawczyk, Michał Grąt, Karolina Grąt, Karolina Wronka, Maciej Krasnodębski, Jan Stypułkowski, Łukasz Masior, Wacław Hołówko, Joanna Ligocka, Paweł Nyckowski, Tadeusz Wróblewski, Rafał Paluszkiewicz, Waldemar Patkowski, Krzysztof Zieniewicz, Leszek Pączek, Piotr Milkiewicz, Urszula Ołdakowska-Jedynak, Bogusław Najnigier, Krzysztof Dudek, Piotr Remiszewski, Ireneusz Grzelak, Oskar Kornasiewicz, Marcin Kotulski, Piotr Smoter, Mariusz Grodzicki, Michał Korba, Piotr Kalinowski, Michał Skalski, Krzysztof Zając, Rafał Stankiewicz, Marta Przybysz, Bartosz Cieślak, Łukasz Nazarewski, Małgorzata Nowosad, Konrad Kobryń, Michał Wasilewicz, Joanna Raszeja-Wyszomirska, Jolanta Piwowarska, Dorota Giercuszkiewicz, Joanna Sańko-Resmer, Sławomir Rejowski, Monika Szydłowska-Jakimiuk, Barbara Górnicka, Bogna Wróblewska-Ziarkiewicz, Michał Mazurkiewicz, Grzegorz Niewiński, Jacek Pawlak and Ryszard Pacho

Abstract

Liver transplantation is a well-established treatment of patients with end-stage liver disease and selected liver tumors. Remarkable progress has been made over the last years concerning nearly all of its aspects.

The aim of this study was to evaluate the evolution of long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery (Medical University of Warsaw).

Material and methods. Data of 1500 liver transplantations performed between 1989 and 2014 were retrospectively analyzed. Transplantations were divided into 3 groups: group 1 including first 500 operations, group 2 including subsequent 500, and group 3 comprising the most recent 500. Five year overall and graft survival were set as outcome measures.

Results. Increased number of transplantations performed at the site was associated with increased age of the recipients (p<0.001) and donors (p<0.001), increased rate of male recipients (p<0.001), and increased rate of piggyback operations (p<0.001), and decreased MELD (p<0.001), as well as decreased blood (p=0.006) and plasma (p<0.001) transfusions. Overall survival was 71.6% at 5 years in group 1, 74.5% at 5 years in group 2, and 85% at 2.9 years in group 3 (p=0.008). Improvement of overall survival was particularly observed for primary transplantations (p=0.004). Increased graft survival rates did not reach the level of significance (p=0.136).

Conclusions. Long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery are comparable to those achieved in the largest transplant centers worldwide and are continuously improving despite increasing recipient age and wider utilization of organs procured from older donors.

Open access

Marek Krawczyk, Michał Grąt, Krzysztof Barski, Joanna Ligocka, Arkadiusz Antczak, Oskar Kornasiewicz, Michał Skalski, Waldemar Patkowski, Paweł Nyckowski, Krzysztof Zieniewicz, Ireneusz Grzelak, Jacek Pawlak, Abdulsalam Alsharabi, Tadeusz Wróblewski, Rafał Paluszkiewicz, Bogusław Najnigier, Krzysztof Dudek, Piotr Remiszewski, Piotr Smoter, Mariusz Grodzicki, Michał Korba, Marcin Kotulski, Bartosz Cieślak, Piotr Kalinowski, Piotr Gierej, Mariusz Frączek, Łukasz Rdzanek, Rafał Stankiewicz, Konrad Kobryń, Łukasz Nazarewski, Dorota Leonowicz, Magdalena Urban-Lechowicz, Anna Skwarek, Dorota Giercuszkiewicz, Agata Paczkowska, Jolanta Piwowarska, Remigiusz Gelo, Paweł Andruszkiewicz, Anna Brudkowska, Renata Andrzejewska, Grzegorz Niewiński, Beata Kilińska, Aleksandra Zarzycka, Robert Nowak, Cezary Kosiński, Teresa Korta, Urszula Ołdakowska-Jedynak, Joanna Sańko-Resmer, Bartosz Foroncewicz, Jacek Ziółkowski, Krzysztof Mucha, Grzegorz Senatorski, Leszek Pączek, Andrzej Habior, Robert Lechowicz, Sławomir Polański, Elżbieta Leowska, Ryszard Pacho, Małgorzata Andrzejewska, Olgierd Rowiński, Sławomir Kozieł, Jerzy Żurakowski, Bogna Ziarkiewicz-Wróblewska, Barbara Górnicka, Piotr Hevelke, Bogdan Michałowicz, Andrzej Karwowski and Jerzy Szczerbań

1000 Liver Transplantations at the Department of General, Transplant and Liver Surgery, Medical University of Warsaw - Analysis of Indications and Results

The aim of the study was to analyze indications and results of the first one thousand liver transplantations at Chair and Clinic of General, Transplantation and Liver Surgery, Medical University of Warsaw.

Material and methods. Data from 1000 transplantations (944 patients) performed at Chair and Clinic of General, Transplantation and Liver Surgery between 1994 and 2011 were analyzed retrospectively. These included 943 first transplantations and 55 retransplantations and 2 re-retransplantations. Frequency of particular indications for first transplantation and retransplantations was established. Perioperative mortality was defined as death within 30 days after the transplantation. Kaplan-Meier survival analysis was used to estimate 5-year patient and graft survival.

Results. The most common indications for first transplantation included: liver failure caused by hepatitis C infection (27.8%) and hepatitis B infection (18%) and alcoholic liver disease (17.7%). Early (< 6 months) and late (> 6 months) retransplantations were dominated by hepatic artery thrombosis (54.3%) and recurrence of the underlying disease (45%). Perioperative mortality rate was 8.9% for first transplantations and 34.5% for retransplantations. Five-year patient and graft survival rate was 74.3% and 71%, respectively, after first transplantations and 54.7% and 52.9%, respectively, after retransplantations.

Conclusions. Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Liver failure caused by hepatitis C and B infections remains the most common cause of liver transplantation and structure of other indications is consistent with European data.