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  • Author: Nóra Papp x
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Comparative Histological Evaluation of the Fruit of Ribes nigrum and Ribes rubrum


To complete the wide range of studies on chemical composition and pharmacological potential of the fruit of Ribes nigrum and Ribes rubrum, this work aimed to perform a comparative morpho-anatomical characterization of the fruits of both species and complete previously records of black currant as frequently studied species. Microslides of fruits were made with rotation microtome, and then cross sections were stained with toluidine blue. Documentation and evaluation were carried out in microphotos. In R. rubrum, the epidermis cells are ovoid to round, while those of R. nigrum are rectangular to almost round. Under the epidermis, in both fruits, there are two layers of oval hypodermal cells. Underneath the hypodermal layers, parenchyma cells of different size with thin walls and scattered collateral closed bundles were detected. The seeds are embedded in a gelatinous sheath having large thin-walled cells. Endocarp separates the arillar tissue from parenchyma cells, in addition, a gap can be found among these layers, endocarp, arillar tissue, and seeds. The seed coat consists of sclerenchyma cells in both species. In conclusion, histological differences and similarities were described in the fruits of the selected Ribes species, highlighted the first morpho-anatomical description of the berry of Ribes rubrum.

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The Care of Central Venous Catheters in the Oncopediatric Department


Introduction: Childhood cancer, with its major psycho-social and health impact, needs long-term chemotherapy. Increasing the intensity of treatment results in improved outcomes of hematological malignancies and solid tumors. As cytostatics have a vascular irritating effect and multiple peripheric venous punctures cause pain, insertion of a long-term central venous catheter (CVC) during chemotherapy is often necessary.

Materials and methods: All pediatric patients (aged below 18 years) with hematologic and malignant pathologies who underwent CVC insertion at the Pediatric Hemato-oncology Department of the County Emergency Clinical Hospital of Tîrgu Mureș in the February 2014 – May 2016 period were enrolled in the study.

Results: We recorded 24 cases who received central venous catheters, out of which 14 patients received tunneled CVC, 7 patients port CVC, and 3 patients received initially tunneled CVC which was changed with port CVC. Tunneled catheters were preserved in average for 186.06 days and portacaths for 256.6 days. For infection prophylaxis and treatment every child received adequate antibiotic medication.

Conclusions: The use of central lines in pediatric hemato-oncology is accessible and benefic not only for increasing patient comfort, but also to ease the nurses' work, who are often overburdened.

Open access