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  • Author: Mustafa Ergun x
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Abstract

Businesses today face great competition in their operations, making it necessary for them to adopt a “customer-oriented” approach. In this competitive environment, where customers are more valuable, enterprises accrue great advantages from an understanding of the characteristics of the target audience in all dimensions. This is where the importance of geo-marketing and demographic segmentation for enterprises emerges. This study performed a geo-demographic segmentation of the urban neighbourhoods of Eskişehir province and sought to determine the characteristics of the people living in these neighbourhoods at the household level. The Groups created using the SPSS package program as well as Principal Components Analysis (PCA) and Hierarchical Clustering Analysis were then mapped on the GIS platform as urban neighbourhoods.

Abstract

Objective: To evaluate the prevalence of HPV DNA and cervical cytological abnormalities, to compare cervical cytology results and HPV DNA and to define HPV types distribution in a large series of Turkish women who have undergone HPV analysis in hospitals that are members of the Turkish Gynecological Oncology Group.

Material and Method: Between 2006 and 2010, a total of 6388 patients’ data was retrospectively evaluated at 12 healthcare centers in Turkey. Demographic characteristics, cervical cytology results, HPV status and types were compared.

Results: The mean age of the patients was 38.9±10.2. Overall, 25% of the women were found to be HPV positive. Presence of HPV-DNA among patients with abnormal and normal cytology was 52% and 27%, respectively. There was significant difference with respect to decades of life and HPV positivity (p < 0.05). HPV was positive in (within the HPV (+) patients) 37%, 9%, 27%, 20%, 22%, and 41% of the ASCUS, ASC-H, LSIL HSIL, glandular cell abnormalities, and SCC cases respectively The most common HPV types in our study were as follows; HPV 16 (32%), HPV 6 (17%), HPV 11 (9%), HPV 18 (8%), HPV 31 (6%), HPV 51 (5%), HPV 33 (3%).

Conclusion: In this hospital based retrospective analysis, HPV genotypes in Turkish women with normal and abnormal cytology are similar to those reported from western countries. Further population based prospective multicenter studies are necessary to determine non-hospital based HPV prevalence in Turkish women