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Jalaluddin Akbar, Syed Tanveer Shah, Muhammad Naeem Khan and Ahmad Naeem

Abstract

Natural landscape is an important resource for mountainous regions and play crucial role in tourism development. Tourism play a key role in economic development of a country. Developing tourist areas is the key to meet the expectations of mountain inhabitants, tourists, and the general public outside of mountainous areas. In order to know tourist perception, problems, and role of landscape & horticulture plants in the field of tourism. A research study entitled “Role of facilities available and un-available in attracting of tourist in swat valley Pakistan “The data was collected from the respondents through a questionnaire survey and analyzed using percentages, frequencies and Chi-square test (where applicable). The analyzed data revealed that most of the respondent (55 %) considered natural green environment as a reason for their visit and 67 % respondents wanted to visit with their friends and were satisfied with the tourist area, respectively. Most of the respondent (39 %) observed throwing of surplus food as major waste materials which turned the beautiful green environment into unattractive environment. Most of the visitors (52 %) dislike un-cleanliness of the locality, 74% respondents felt ill effect due to deforestation.53 % tourist disagree with the current maintenance of the locality by tourism department. The most missed facilities were non availability of dustbins and children playing areas. 75 % respondents agreed with the fact that most of the people (local inhabitants as well as tourist) were unaware with regard to maintenance activities of the area 15.7 % respondent agreed that road system should be improved to access most of the greenery in the locality, respectively to aware local people and tourist regarding maintenance of the locality will improve tourism in Swat valley. The studies need to be develop for the improvement of existing as well as artificial landscape of the tourist area (Kalam and Malamjabba) of Swat valley.

Open access

Naureen Shehzadi, Khalid Hussain, Muhammad Islam, Nadeem Irfan Bukhari, Muhammad Tanveer Khan, Muhammad Salman, Sabahat Zahra Siddiqui, Aziz-Ur Rehman and Muhammad Athar Abbasi

Abstract

The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate, 5-[(4-chlorophenoxy) methyl]-1,3,4-oxadiazole-2-thiol (OXCPM), in bulk and stressed solution, in order to find out the intrinsic stability behavior of the compound. Isocratic elution was carried out at a flow rate of 1.0 mL min-1 through a Promosil C18 column maintained at 25 °C, using the mobile phase comprising acetonitrile and aqueous o-H3PO4 (pH 2.67) (1:1, V/V). Detection was performed at 258 nm. The response of the detector was linear in a concentration range of 1.25-50.00 μg mL-1 with the correlation coefficient of 0.9996 ± 0.0001. Cumulative intra-day, inter-day and inter-instrument accuracy (99.5 ± 1.0, 100.2 ± 1.0 and 100.3 ± 0.4 %, resp.) with RSD less than 5 % indicated that the method was accurate and precise. The resolution and selectivity factor (>2 and >1, resp.), particularly in copper metal- and dry-heat-stress solutions, depicted the selectivity of the method. OXCPM remained stable under hydrolytic (acidic and neutral pH, ≤ 37 °C), photolytic and moist heat stress conditions. Under alkaline conditions (hydrolytic and photolytic), polar products were formed that eluted very fast through the column (tR < 3.75 min). At room temperature, the compound was susceptible to oxidation by hydrogen peroxide and transition metals. The ionogram of most of the stress solutions indicated the presence of a product having m/z 256, which might be a result of N- or Smethylation or -SH oxidation. The results of the study indicate that the method is selective, sensitive and suitable to be used for determination of OXCPM in bulk and under stress conditions.