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Open access

Anca Chiriac, Mihai Mares, Cristian Podoleanu, Cosmin Moldovan and Simona Stolnicu

Abstract

Introduction: Lately, a new idea has caught the attention of young people of both genders, being debated in consultation rooms, during classes, and especially on social media: is using horse shampoo for human hair wrong or not?

Material and methods: A simple questionnaire about horse shampoo and its use in humans was addressed to 85 students.

Results: Thirty-eight responders were aware of its existence, 27 have tried it and 3 were still using it as a weekly shampoo. All positive responders were young women who declared being completely satisfied by horse shampoo and none of them have reported side effects.

Conclusion: Although it has good reviews, horse shampoo is not available in human pharmacies. As dermatologists, we are still looking for an answer.

Open access

Irina Rosca, Andra-Cristina Bostanaru, Bogdan Minea, Valentin Nastasa, Iulian Gherghel, Carmen-Valentina Panzaru, Mihai Mares and Valentina Ruxandra Moroti-Constantinescu

Abstract

Background: During the last two decades a major increase in the proportion of severe fungal infections has been noted due to the excessive use of broad-spectrum antibiotics, catheters, and a growing number of immunocompromised patients.

Objectives: This is the first investigation providing complete data regarding the phenotypic and genotypic profiles of Candida albicans (C. albicans) isolates in Romanian patients.

Methods: We investigated 301 isolates in terms of genotype determination (G), resistogram (R), phospholipase activity (Pl), haemolysis (Hl), proteinase activity (Pt), and biofilm formation (BF).

Results: The analyzed isolates of C. albicans showed low values for Pt (61.73%), Hl (95.49%), and BF (60.71%), and did not present any Pl activity (92.23%). More than half of the investigated samples were genotype A with 450 bp (52.92%) and the majority (86.19%) were resistant to sodium selenite (A), boric acid (B), sodium periodate (D) and silver nitrate (E), but sensitive to cetrimide (-). One-way ANOVA analysis revealed significant effects of the infection site on biofilm formation (p = 0.0137) and no significant correlation was found between the genotype (A, B, C) and the infection site (p =0.449).

Conclusions: Based on the obtained results it can be concluded that C. albicans isolates in Romanian patients exhibit different genotypic and phenotypic patterns, and no significant correlations between genotype and infection site could be observed.