Aim of the present paper is to establish fractional integral formulas by using fractional calculus operators involving the generalized (p, q)-Mathieu type series. Then, their composition formulas by using the integral transforms are introduced. Further, a new generalized form of the fractional kinetic equation involving the series is also developed. The solutions of fractional kinetic equations are presented in terms of the Mittag-Leffler function. The results established here are quite general in nature and capable of yielding both known and new results.