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Rudīte Lagzdiņa, Leons Blumfelds, Maija Rumaka and Līga Aberberga-Augškalne

Abstract

Eating habits with uniform food preferences and increased energy intake can contribute to increased gain of body fat. An adequate diet, body self-evaluation, and recognition of unhealthy nutrition patterns should promote appropriate corrective actions. The aim of the present study was to determine whether energy intake, food diversity and corrective modification of body mass differed among student groups with low, normal and high body fat percentage. The study involved 737 (158 male and 579 female) students of the Rîga Stradiòð University (age 18-49 years). Dietary behaviour was determined using self-administered questionnaire. Body fat percentage was determined with a Tanita MC-180 bioimpedance analyser. Fluid and food intake, as well as physical activity before the test was restricted. The results showed that 15% of students in the low, 38% in the normal and 62% in the high body fat percentage groups considered that they eat too much. In the low, normal and high body fat percentage groups of students, 27%, 37% and 42%, respectively, agreed that they do restrict food intake. There were no significant differences in normalised energy intake and food diversity indexes between these student groups. Students in the high body fat percentage group more frequently admitted eating to much, and their corrective behaviour was associated more with reduced amounts of eaten food rather than minimisation of energy intake and increased food diversity. In all fat percentage groups, female students more frequently admitted that they eat too much and more often tended to restrict food intake than male students.

Open access

Pēteris Tretjakovs, Juris Hofmanis, Dace Hofmane, Gita Krieviņa, Leons Blumfelds, Vitolds Mackēvičs, Aivars Lejnieks and Guntis Bahs

Abstract

The aim of the present study was to evaluate plasma levels of chemerin, myeloperoxidase (MPO), fibroblast growth factor-21 (FGF-21), thioredoxin reductase-1 (TrxR1), and matrix metallopeptidase-9 (MMP-9) in acquired aortic valve (AoV) stenosis patients to determine correlations between the studied cellular factors, and also clarify the predictive values of these factors as biomarkers in AoV stenosis. AoV stenosis patients were classified into three groups: 17 patients with mild AoV stenosis; 19 with moderate and 15 with severe AoV stenosis. Twenty-four subjects without AoV stenosis were selected as a control group. Our findings suggest that AoV stenosis might be associated with increased chemerin, TrxR1, MPO, and FGF-21 levels in plasma. Moreover, these factors and also MMP-9 already reached statistically significantly elevated levels in the early stages of AoV stenosis, but MPO levels were more pronounced in patients with moderate and severe AoV stenosis. Chemerin was correlated with all of the studied cytokines; TrxR1 and MMP-9 were correlated with several other cellular factors. Our findings (by ROC analysis) suggest that MPO and chemerin might serve as specific and sensitive biomarkers for AoV stenosis without grading the severity, but, in relation to mild AoV stenosis, TrxR1, FGF-21, and MMP-9 also reached good or moderate levels as biomarkers. The cellular factors might serve as novel diagnostic and prognostic biomarkers in AoV stenosis patients, while chemerin and MPO may be more powerful.