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Krzysztof Kołodziejczyk

Hiking Trails for Tourists in the "Chełmy" Landscape Park - Assessment of Their Route and Infrastructure Development

Introduction. The objective of the work was to assess the development of hiking trails for tourists and their infrastructure in the "Chełmy" Landscape Park in Lower Silesia. Material and methods. The analysis concerned a network of tourist trails whose coherence and shape were evaluated based on the indices derived from the graph theory. Also the correspondence between the names given to some trails with the tourist attractions accessible via such trails was assessed, and their number was compared to the length of the relevant trails. The analysis of the development of infrastructure for hiking tourists was conducted based on the results of local stocktaking and determination of tourist traffic density. Results. The obtained results show that the network of trails across the Park is quite well developed and coherent, despite the diversity of infrastructural development. The correspondence between the names of trails with their tourist attractions was confirmed with some reservations. Conclusions. Diverse trails in the studied area should be integrated into a coherent network by their similar development level, and in particular by introducing uniform marking standards. It would be also worth providing better access to some attractions for hiking tourists by introducing appropriate access routes.

Open access

Krzysztof Kołodziejczyk

Abstract

The article describes the feasibility of numerical simulation of sedimentation process of coal suspension, with high concentration, using the Ansys Fluent package, with the assumption monodisperse grain composition of the disperse phase of the suspension. The analysis contains selection of computational model, determine the parameters for analysis and comparison of the results with laboratory tests. To comparison laboratory measurement and numerical simulation sedimentation test was used. In the analysis was used suspension from the coal purification process.

Open access

Dagmara Chylińska and Krzysztof Kołodziejczyk

Abstract

The aim of the article is to assess the role of degraded landscapes in tourism. The authors try to answer questions about the contexts in which such landscapes may be found in relation to those complex phenomena concerning the human need for travel, leisure, cognition and experience. They also pose questions about the physical and symbolic limits to tourism and recreation in degraded landscapes. The work is based on a literature review and observations on chosen degraded landscapes (mostly industrial and post-industrial) located at the Czech foreground of the Ore Mountains (Czech Krušné Hory, German Erzgebirge).

Open access

Adrian Głogowski, Zbigniew Marczyński, Michał Krzysztof Kołodziejczyk, Jerzy Jambor, Marta Kinga Stefan and Marian Mikołaj Zgoda

Summary

Introduction: Dietary supplements are a good way to supplement the deficiency of certain micronutrients and organic components (therapeutic agents) in human body. They are most often available in concentrated form as tablets, capsules, powder or liquid.

Objective: To investigate morphological parameters and the pharmaceutical availability of coated tablets – dietary supplements – that contain selected pharmacopeial titrated dry plant extracts.

Methods: Testing of the effective time of the tablet surface erosion was performed in model acceptor fluids using pharmacopeial methods in static (Erweka apparatus) and dynamic (unlimited diffusion method) conditions. Furthermore, morphological parameters of tablets (the original shape of an ellipse) as well as their hardness were determined.

Results: The effective erosion time was determined by conductometric method using carboxymethylcellulose sodium salt (NaCMC) contained in the tablet. The content of gum arabic and NaCMC in the tablet testifies that the granulate was produced using the “wet granulation” technique which resulted in high hardness of original, esthetic, elliptical tablets and in prolonged disintegration time (erosion).

Conclusions: The used excipients: gum arabic and NaCMC for the production of the tested tablets containing selected dry plant extracts result in their high hardness. The tested dietary supplements are characterized by esthetic design, original shape, and prolonged disintegration time which affects the pharmaceutical availability.

Open access

Bartosz Fotschki, Adam Jurgoński, Jerzy Juśkiewicz, Krzysztof Kołodziejczyk and Michał Sójka

Abstract

The aim of this study was to scrutinise if the dietary addition of a low-pectin fibre preparation obtained from apple pomace, the by-product of apple concentrate processing, is able to favourably affect the gut metabolism, antioxidant status and blood bio-markers of the organism, as it takes place when apple fibre is present in the diet as an unprocessed ingredient. The nutritional experiment was performed on rats allocated to 2 groups of 10 animals each and fed for 2 weeks with either a control cellulose-containing diet or an experimental low-pectin apple fibre-containing diet. To induce metabolic disorders a diet rich in saturated fat and fructose was used in both diet-specific groups. The dietary apple fibre preparation (AFP) significantly reduced the activity of sucrase and maltase in the mucosa of the small intestine. In the caecal digesta, the dietary AFP significantly increased bacterial α-glucosidase and α-galactosidase activity, whereas bacterial β-glucuronidase activity was significantly reduced. Also, the content of short chain fatty acids in the caecal digesta was significantly increased after the AFP supplementation. In the blood serum, the dietary AFP significantly reduced the glucose concentration, and decreased the ratio of total cholesterol to HDL cholesterol. In conclusion, the tested dietary AFP is still able to favourably affect the gut metabolism and can also ameliorate blood glucose concentration, which seems to be related to the inhibition of mucosal disaccharidase activities. However, the analysed preparation has no influence on the antioxidant status of the organism and may trigger adverse effects on cholesterol metabolism.

Open access

Violetta Sulżyc-Bielicka, Lidia Kołodziejczyk, Sylwia Jaczewska, Dariusz Bielicki, Józef Kładny and Krzysztof Safranow

Prevalence of Cryptosporidium sp. In Patients with Colorectal Cancer

Parasitic protozoans of the Cryptosporidium genus are intracellular intestinal parasites of mammals, causing cryptosporidiosis. Clinically, cryptosporidiosis manifests as chronic diarrhoea. Individuals with immune disorders, including those with neoplasms, are at risk of symptomatic invasion.

The aim of the study was the evaluation of Cryptosporidium sp. prevalence in patients with diagnosed colorectal cancer.

Material and methods. The studied group encompassed 87 patients with diagnosed colorectal cancer, undergoing surgery at the Department of General and Oncological Surgery, Pomeranian Medical University, in the years 2009-2010. Immunoenzymatic tests for Cryptosporidium sp. on faeces samples were performed with the use of commercial test kit, ProSpecT®Cryptosporidium Microplate Assay (Remel Inc).

Results. The presence of Cryptosporidium sp. was found in 12.6% of studied patients with colorectal cancer. The performed statistical analysis did not reveal any correlation between Cryptosporidium sp. infection and gender, age, neoplasm advancement stage as per Astler-Coller scale, neoplasm differentiation grade, or neoplastic tumour localisation in relation to the splenic flexure.

Conclusions. There was found high prevalence of Cryptosporidium sp. in patients with colorectal cancer. It was comparable to the prevalence reported for patients with immune deficiency.

Open access

Jan Kulig, Grzegorz Wallner, Michał Drews, Mariusz Frączek, Arkadiusz Jeziorski, Wojciech Kielan, Piotr Kołodziejczyk, Anna Nasierowska-Guttmejer, Teresa Starzyńska, Krzysztof Zinkiewicz and Marek Krawczyk

Open access

Jerzy Juśkiewicz, Adam Jurgonski, Krzysztof Kołodziejczyk, Monika Kosmala, Joanna Milala, Zenon Zduńczyk, Bartosz Fotschki and Ewa Żary-Sikorska

Abstract

In two experiments on rats it was analyzed whether the lowering rate of postprandial glycaemia depends on the degree of polymerization of strawberry ellagitannins (ET). Two types of highly-concentrated polyphenolic extracts were used, one rich in monomeric ET (ETM; 94.9% polyphenols and 67% ETM in it), the second in dimeric ET (ETD; 95.9% polyphenols, and 78.0% ETD in it). The experiment 1 comprised three oral sugar tolerance tests, GTT (with glucose; to examine monosaccharide transport across epithelium), SuTT (with sucrose; to examine the activity of mucosal disaccharidase) and StTT (with starch; to examine the action of salivary alpha-amylase, and then of pancreatic amylase in the small intestine as well as all the aforementioned mechanisms), while in the experiment 2 the healthy and pre-diabetic rats were subjected to 1-h small intestine perfusion with fluids containing glucose or sucrose. Considering the shape of blood glucose concentration curve following GTT and SuTT, as well as changes in glycaemia and mucosal disaccharidases activity observed within and after small intestine perfusion, the ETM (vs. ETD) extract more positively mitigated sugar-induced post-prandial glycaemic load. Contrary to expectations, the effect of extracts on pre-diabetic rats was negligible. The extract ETD, in turn, potently mitigated starch-induced postprandial glycaemic load during test StTT. The results clearly showed that the separate mechanisms (glucose transport across the intestine, intestinal mucosal disaccharidases inhibition activity, pancreatic α-amylase inhibitory activity) leading to decreased postprandial glycaemia upon dietary administration of strawberry ellagitannins largely depended on their chemical structure, i.e. degree of polymerization.