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  • Author: Krisztina Horicsányi x
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Abstract

Drug-eluting stents provide a solution for treating restenosis in arteries expanded by using conventional bare metal stents, but there are a small number of publications on the processes of coating damage established due to the various effects that occur during the life cycle of the stent. In the current research damage to the coating was investigated along with the effects of damage on the corrosion resistance of the stent in multiple ways. This research investigates not only traditional drug eluting stents with polymer matrix, but also the new generation of polymer-free types.

Abstract

During implantation, stents are delivered in crimped state to the narrowed lesion, where they are expanded to the desired size by the balloon. Due to insufficient size selection or high resistance to plaque, the stent is often widened by the expansion pressure to a level greater than the nominal pressure specified by the manufacturer. Depending on the degree of overpressure, the nominal diameter of the stent may change by several tenths of a millimetre. Numerous studies have dealt with the physiological effects of overexposure and stenogenic stress, but so far no studies have been carried out to investigate the stent coating and corrosion properties of the stent. In our research a widely used drug-eluting, platinum-chromium alloyed steel stent was observed with an inflation pressure of 12 and 18 bar. Scanning electron microscopy revealed lesions of the coating and potentiodynamic tests were performed to determine the corrosion rate.