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  • Author: Khrystyna Kozak x
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Abstract

Due to the fact that the number of natural disasters in the world has increased in recent years, experts note that climate change is the cause. As a consequence of the nature of the needs to improve the fuel and energy complex in the countries in world. This solution could be solar energy and similar energy sources. The paper presents the classification of energy-efficient houses proposed by international standards and its critical analysis. Emphasis is placed on the problem of improving solar collectors integrated into the construction of buildings. The paper presents the temperature characteristics of an experimental solar collector. For the experimental solar collector combined with the translucent facade of the building, thermal characteristics are set, in particular, such as thermal capacity and thermal efficiency.

Abstract

One of the most promising energy sources is solar energy, which is confirmed by the growth in the development of renewable energy for European countries. The main goal of research is to design and implement the latest energy systems for passive buildings using renewable energy. In this paper is documented the optimal operation stages of the solar heat supply system were investigated with recommendations for further development of the design and construction of passive buildings in Ukraine South.

Abstract

Background

Chronic obstructive pulmonary disease (COPD) continues to cause a heavy health and economic burden in the Europe and around the world. Arterial hypertension (AH) is considered as one of the principal COPD-associated comorbidi-ties. However, no data for association between gene polymorphism and AH in patients with COPD in Ukraine have ever been internationally published. We assessed the genotype and allele frequencies of angiotensinogen (AGT) M235T polymorphisms in patients with COPD and comorbid AH.

Methods

The study group consisted of 96 patients: Group 1 (25 individuals with COPD), Group 2 (23 individuals with AH) and Group 3 (28 individuals with COPD and AH). The control group consisted of 20 healthy subjects. M/T genotypes of AGT were determined by polymerase chain reaction amplification.

Results

The results of the study have not demonstrated any significant impact of alleles of AGT genes on the occurrence of diseases such as COPD, AH and combinations thereof. However, analysis of odds ratio has demonstrated the presence of a trend towards a protective role of the M allele of the AGT gene concerning occurrence of COPD, AH and their combinations. At the same time, the presence of the T allele of the AGT gene may increase the risk for occurrence of the above-mentioned diseases.

Conclusions

The study that we have conducted suggests that the presence of T allele of the AGT gene at position 235 of the peptide chain both in homozygous and heterozygous states may increase the risk for AH in patients with COPD.