The study examines the acute response of bone turnover markers to two different single bouts of resistance exercises in women. Serum bone alkaline phosphatase and sclerostin concentration were measured before, 24 and 48 hours after the interventions to detect the dynamics of bone turnover. Subjects performed two exercises and a control experiment without exercise (CONTR) on different occasions, with 3-week breaks between the interventions, in a random order. First exercises protocol had a constant resistance of 75 % 1 RM (ISOF). Second, serial stretch loading (SSL), was isokinetic: velocity of concentric and eccentric phase of the movement was 50 and 40 cm/s, respectively. Short stops were incorporated into both phases of the movement after every 20 mm, resulting in a frequency of the force peaks of 10 Hz in concentric as well as in eccentric phase. Both protocols consisted of 6 sets of 6 repetitions and 2-minute resting periods. The exercises interventions had no statistically significant effect on either bone turnover marker concentration at any of the time points.