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Iulian Ilie and Gheorghe Ion Gheorghe

Abstract

The smart mechatronic microsystem in 4D is designed and built for metrological and indstrial measurements and applications. The intelligent mechatronic system consists of 3 electric linear axes and a rotation system mounted on the linear Z-axis, which increases the capacity of the measuring and positioning system, allowing further expansion of the technical and technological services of the entire mecatronic system by connecting grippers, palpator, stylus module, etc.

Open access

Adina N. Hadade, Caius M. Breazu, Iulian V. Ilie and Calin I. Mitre

Abstract

Sepsis and septic shock are major healthcare problems, resulting in high morbidity and mortality. The Surviving Sepsis Campaign (SSC), which standardised the approach to sepsis, was recently updated. Strategies to decrease the systemic inflammatory response have been proposed to modulate organ dysfunctions. Endotoxin, derived from the membrane of Gram-negative bacteria, is considered a major factor in the pathogenesis of sepsis. Endotoxin adsorption, if effective, has the potential to reduce the biological cascade of Gram-negative sepsis.

We present a case of a 64-year-old man with severe Gram-negative sepsis, following purulent peritonitis secondary to rectosigmoid adenocarcinoma. To reduce the amplitude of the general effects of endotoxins we used a novel device, the Alteco® LPS Adsorber (Alteco Medical AB, Lund, Sweden), for lipopolysaccharide (LPS) adsorption.

The efficacy markers were: the overall haemodynamic profile, translated into decreased vasopressor requirements, the normalisation of the cardiac index, the systemic vascular resistance index combined with the lactate level and the reduction in procalcitonin (PCT) levels. A decrease in the sequential organ failure assessment (SOFA) score at twenty-four hours was demonstrated.

The clinical course following treatment was favourable for the days immediately following the treatment.This was attributed to the removal of endotoxin from the systemic circulation. The patient died one week after the endotoxin removal session, developing an ischemic bowel perforation with subsequent multiple organ failures.

Open access

Gheorghe Ion Gheorghe, Anghel Constantin and Iulian Ilie

Abstract

The current scientific work show for the first time, (i) a new complex mixmechatronic concept of integration and fusion in the structures of smart technical and technological systems and (ii) the systems of electronic control for holistic physical-virtual assembly.

The content of the paper highlight some results of professional researches in Mechatronics and Cyber-Mix Mechatronics fields at the National Institute of Research and Development in Mechatronics and Measurement Technique– Bucharest and also at Politehnica University of Bucharest (PUB) from Romania. Some of these results are in the process of transfer and capitalization to the industry, economy and society.

Open access

Elena-Teodora Tâlvan, Călin Ilie Mohor, Daniel Chisnoiu, Iulian Mihai Făgețan, Constantin-Dan Tâlvan, Victor Cristea and Radu Septimiu Câmpian