Alienation is a recurring literary subject in the United States. Its peculiarity is occasioned by the phenomenon of racial segregation, among others, with which the society is characterized. Thus, considerable critical attention has been given to the causes as well as the attendant socio-political, economic and psychological imports on the victims. From a psychological perspective, specifically, this paper engages in a comparative analysis of the effects of alienation on characters of African American and Native American origins produced by the same system in two novels which have African American and Native American roots – Toni Morrison’s The Bluest Eye and James Welch’s Winter in the Blood, respectively. In order to understand the variance and/or convergence in the personality formations of the African American and Native American characters in the narratives, consequent upon the racially alienating system, the paper adopts Carl Jung’s psychological theory of personality typology, labelled introversion and extraversion, with a view to assessing how, typically, persons of these origins are more likely to react to the socio-political, cultural and economic situations affecting them as minority ethnic groups in the United States.