Nowadays, the focus shifts from information and communication technology access to skills and knowledge. Moreover, lack of digital skills is an obstacle in the process of learning new digital competences using technologies and e-learning. The objective of this research is to investigate how to facilitate students to use the acquired digital skills in practice and to evaluate the impact of students’ previous knowledge level. Based on the e-inclusion digital skills model, the author develops two research questions: How students’ previous experience impacts practical usage of the acquired ICT skills and How students’ self-assessment correlates with practical usage of the acquired ICT skills. The research employs student-centred learning theory, where the learning process is based on students’ active action, experience and values. The research is based on a literature review and one case study. The results of this study confirm the relationship of the e-inclusion digital skills model with the knowledge level acquired and its usage.