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  • Author: Hakan Mutlu x
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The Restriction of Individual Performance of PGPR on Maize Nutrient Uptake by Antagonistic Relations


Recent studies have shown that certain soil microorganisms are capable to sustain plant nutrition in both conventional and organic agriculture; however, yet further studies needed for evaluation of the factors affecting PGPR performance. The goal of this research was to evaluate performance of natural bacteria relative to nutrient uptake and biomass development in corn (Zea mays L.) as it is related to conventional production systems. Soils have been collected from forested areas of Lake Region. The isolated bacteria have been tested at the conventional farm in Mediterranean region. Nine isolated and one cocktailed bacteria suspensions have been applied to rhizosphere of corn plants under regular cultivation practices in conventional production systems. The results revealed that all isolates are showing either positive or negative effect on both plant performance and nutrient uptake. No statistical differences were observed on grain yield; however, Isolates 3 and 9 showed improved grain-excluded biomass performances by 37.1% and 38.5% respectively. Phosphorus, zinc and manganese uptakes were the highest in Isolate 6 whereas the highest Fe uptake was determined in Isolate 8 at the tuft formation stage. Although all isolates represent their specific individual performances as far as any plant nutrient uptakes are concerned, their cocktail was not as effective. That happened probably due to competition between the isolates.

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Endothelial Dysfunction Markers in Low Cardiovascular Risk Individuals: Comparison of Males and Females


Background: Cardiovascular diseases (CVD) account for approximately 50% of the total deaths in Turkey. Most of them are related with atherosclerotic coronary heart disease. Predictive value of endothelial dysfunction markers related with the earliest stage of atherosclerosis has been getting more attention. We hypothesized that differences in endothelial dysfunction biochemical markers among genders would aid to capture proatherogenic activity that was not diagnosed by conventional risk assessment scoring systems.

Methods: We assessed the endothelial dysfuntion markers in 92 Turkish adults who were in the »low CV risk group« according to ESC (European Society of Cardiology)-Score Risk Charts. We compared the males and females.

Results: We observed higher endothelial dysfunction rates in males, with higher median and mean levels of e-NOS, ox-LDL before and after adjustment for HDL lowness and obesity (P=0.018, P=0.036 for NOS; P=0.000, P=0.004 for ox-LDL, respectively). Men had higher hs-CRP levels than females before adjustment (P=0.021). Decreased e-NOS levels were related with FMD for females before adjustment for confounders (P=0.028). We also found significant correlation between e-NOS and ox-LDL levels both before (r=0.360, P<0.001) and after adjustment (r=0.366, P<0.01) for confounders which pointed out the nitrosative stress. In multivariate regression analyses, after adjusting for other endothelial dysfunction markers which were not included in the ESC-risk scoring system, decreased e-NOS levels were independently asssociated with impaired flow mediated dilatation for females (odds ratio 0.3; P=0.038).

Conclusions: Our results underline the importance of gender in evaluating endothelial dysfunction biochemical markers to assess cardiovascular risk for low CV risk indivuals.

Open access
HPV Types in Turkey: Multicenter Hospital Based Evaluation of 6388 Patients in Turkish Gynecologic Oncology Group Centers / Türkiye’deki HPV Tipleri: Türk Jinekolojik Onkoloji Grubuna Üye Merkezlere Başvuran 6388 Hastanın Retrospektif Analizi


Objective: To evaluate the prevalence of HPV DNA and cervical cytological abnormalities, to compare cervical cytology results and HPV DNA and to define HPV types distribution in a large series of Turkish women who have undergone HPV analysis in hospitals that are members of the Turkish Gynecological Oncology Group.

Material and Method: Between 2006 and 2010, a total of 6388 patients’ data was retrospectively evaluated at 12 healthcare centers in Turkey. Demographic characteristics, cervical cytology results, HPV status and types were compared.

Results: The mean age of the patients was 38.9±10.2. Overall, 25% of the women were found to be HPV positive. Presence of HPV-DNA among patients with abnormal and normal cytology was 52% and 27%, respectively. There was significant difference with respect to decades of life and HPV positivity (p < 0.05). HPV was positive in (within the HPV (+) patients) 37%, 9%, 27%, 20%, 22%, and 41% of the ASCUS, ASC-H, LSIL HSIL, glandular cell abnormalities, and SCC cases respectively The most common HPV types in our study were as follows; HPV 16 (32%), HPV 6 (17%), HPV 11 (9%), HPV 18 (8%), HPV 31 (6%), HPV 51 (5%), HPV 33 (3%).

Conclusion: In this hospital based retrospective analysis, HPV genotypes in Turkish women with normal and abnormal cytology are similar to those reported from western countries. Further population based prospective multicenter studies are necessary to determine non-hospital based HPV prevalence in Turkish women

Open access