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  • Author: Goran Petrović x
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Goran Petrović

Summary

This paper analyses the current position of physical culture in the society. It points out the social changes that have substantially suppressed the term physical education and replaced it with the phrase, physical education and sport. In the light of need to reinstate this term into the professional discourse, there was a reminder of the importance and the social scientific contribution to creation of the Theory of physical culture by Milivoje Matić. The critical analysis of the current state of physical education was also conducted. In order to improve physical education classes, a new paradigm of physical education, that will be based on installation of the functional system of physical education and curriculum reform, has to be created. New physical education paradigm signalizes the return to the physical culture - following in professor Matić’s footsteps.

Open access

Goran Savić, Vladimir Vasić, Milan Petrović, Jovan Petrović, Dragoslav Bašić and Jovan Hadži-Đokić

Summary

Testicular microlithiasis is a condition characterized by the ultrasonographic findings with multiple microliths, with the prevalence of 0.6% to 9%. This is a condition of unknown etiology; however, in many cases it may be associated with cryptorchidism, Klinefelter syndrome, Down syndrome, varicocele, testicular torsion and male pseudohermaphroditism. Many retrospective studies point to the association between testicular microlithiasis and testicular cancer.

We report a case of a 50-year-old patient who presented to the urologist because of dysuric symptoms. Ultrasonographic examination of both testicles revealed microcalcifications in large numbers, i.e. “the phenomenon of the starry sky”. More than 20 microcalcifications were present on the cross section of both testicles. Standard laboratory blood tests were normal. Prostate-specific antigen was 1.22 ng/ml. If risk factors for developing cancer are present, some authors recommend a biopsy of the testicles. However, based on the literature review, currently, there is no a strictly defined protocol.

Open access

Miodrag Dimitrijević, Sofija Petrović, Borislav Banjac, Goran Barać and Velimir Mladenov

Summary

The food production at the global level is about to meet its border. Industrialization of agriculture correlates with an explosive enlargement of human population, during XX and at the beginning of XXI centuries. An ongoing process of environmental erosion has been speeding up during that period, not only in our physical surrounding, but also in biodiversity. A new direction in agricultural food production is in demand. Organic food production has been recognized as the way of providing safety and quality food, preserving the environment in the same time. In the other hand new land areas have to be explored for agricultural use, in order to enhance food quantity to meeting the increasing demand for food. These targets set new requirements in plant breeding. To fulfill these requirements the genetic variability harbored in genetic resources has to be preserved, examined and put to good use.

Open access

Zoran Kovacevic, Goran Davidovic, Jelena Vuckovic-Filipovic, Mirjana A. Janicijevic-Petrovic, Katarina Janicijevic and Andrijana Popovic

Abstract

Background: Toxic hepatitis may clinically manifest as other diseases of the liver, where it must always be considered in differential diagnoses of unexplained liver damage, such as poisoning with kombucha tea.

Case report: 47-year old female patient was hospitalized and has consumed daily ounces of kombucha tea. During hospitalization patient was diagnosed with toxic hepatitis and treated with intravenous solutions of hepatic protective and ursodeoxycholic-acid (effective therapy).

Conclusion: Examinations showed that kombucha tea has potential to revert the CCl4-induced hepatic toxicity, but used in overdose can induce toxicity himself.

Open access

Goran Davidovic, Violeta Iric-Cupic, Srdjan Milanov, Ivan Simic, Ziva Zivic and Mirjana Janicijevic-Petrovic

Abstract

Background: Many cardiovascular diseases are associated with obesity, but, despite this fact, obese people live longer than their normal-weight counterparts do. This phenomenon is called the „obesity paradox“.

Aim: Purpose was to investigate the impact of obesity on the final outcome; determine the connection between obesity and heart rate > 80 beats per minute and other risk factors, and presence of „obesity paradox“.

Material and Methods: Research included 140 patients with anterior wall acute STEMI treated in Coronary Unit, Clinical Center Kragujevac form January 2001-June 2006. Heart rate was calculated as the mean value of baseline and heart rate in the first 30 minutes after admission. Body mass index was calculated as the ratio of body weight in kilograms and body height in squared meters, and classified according to the WHO recomendations.

Results: More than 75% obese patients were in both groups, survivors and those who died. In the subgroup with heart rate > 80 results were similar. Obesity had no significant effect on mortality despite the fact that the large number of patients with fatal outcome was obese.

Conclusion: Correlation with acute myocardial infarction and elevated heart rate is evident, but obesity was not independent predictor for mortality which can only partly confirm presence of „obesity paradox“.

Open access

Gorica Vuković, Vojislava Bursić, Tijana Stojanović, Aleksandra Petrović, Sonja Gvozdenac, Mira Starović, Slobodan Kuzmanović and Goran Aleksić

Summary

The undemanding LC-MS/MS method was developed for the synchronized analysis of atropine and scopolamine in maize crop. The dSPE was carried out with 1% acetic acid in acetonitrile/water and a mixture of magnesium sulphate, sodium chloride and sodium citrate. The analytes were separated on a Zorbax XDB C18 column using methanol/water as the mobile phase in gradient mode. The detection was done using a tandem masss spectrometry (MS/MS) in the positive ESI. The tropane alkaloids exhibited excellent linearity in the range of 2-20 µg/kg with the LOQ of 5 µg/kg for maize. The extraction recoveries of atropine and scopolamine were 65.7 and 85.5% with the intraday RSDr 10.25 and 4.29%, respectively. The validated method was appled to real maze samples. One sample contained 18.8 µg/kg of atropine and 6.3 µg/kg of scopolamine.

Open access

Ivana Petrovic, Ivan Stankovic, Goran Milasinovic, Gabrijela Nikcevic, Bratislav Kircanski, Velibor Jovanovic, Srdjan Raspopovic, Nikola Radovanovic and Sinisa U. Pavlovic

Summary

Background: In the majority of patients with a wide QRS complex and heart failure resistant to optimal medical therapy, cardiac resynchronization therapy (CRT) leads to rever se ventricular remodeling and possibly to changes in cardiac collagen synthesis and degradation. We investigated the relationship of biomarkers of myocardial collagen meta bolism and volumetric response to CRT.

Methods: We prospectively studied 46 heart failure patients (mean age 61±9 years, 87% male) who underwent CRT im plantation. Plasma concentrations of amino-terminal pro peptide type I (PINP), a marker of collagen synthesis, and carboxy-terminal collagen telopeptide (CITP), a marker of collagen degradation, were measured before and 6 months after CRT. Response to CRT was defined as 15% or greater reduction in left ventricular end-systolic volume at 6-month follow-up.

Results: Baseline PINP levels showed a negative correlation with both left ventricular end-diastolic volume (r=−0.51; p=0.032), and end-systolic diameter (r=−0.47; p=0.049). After 6 months of device implantation, 28 patients (61%) responded to CRT. No significant differences in the base-line levels of PINP and CITP between responders and nonresponders were observed (p>0.05 for both). During follow-up, responders demonstrated a significant increase in serum PINP level from 31.37±18.40 to 39.2±19.19 μg/L (p=0.049), whereas in non-responders serum PINP levels did not significantly change (from 28.12±21.55 to 34.47±18.64 μg/L; p=0.125). There were no significant changes in CITP levels in both responders and non-responders (p>0.05).

Conclusions: Left ventricular reverse remodeling induced by CRT is associated with an increased collagen synthesis in the first 6 months of CRT implantation.