Żaneta Brudkowska, Małgorzata Tomczyk, Katarzyna Jusiak, Hanna Karakuła-Juchnowicz and Ewa Rudnicka-Drożak
Introduction: Beta blockers are mainly used in treating cardiovascular diseases. However, it has been observed that these drugs have also an anxiolytic potential. Over the years, a number of clinical trials have been conducted aimed at determining the effectiveness of beta blockers in treating anxiety disorders.
The aim of the article: The main objective of the article is to present the significance and position of adrenolytic drugs in the pharmacotherapy of anxiety disorders on the basis of available literature. Moreover, the authors also decided to take into account the data from current research results, considering the problem of side effects of using adrenolytic drugs - especially the controversial reports on their effect on the development of affective disorders.
Method: An analysis was conducted of articles from Medline/PubMed database, selected on the basis of the following key words: anxiety disorders, beta blockers, adrenolytic drugs, as well as on the basis of their dates of publication: 1960-2017. In order to conduct a reliable and complete review of literature, the authors decided to include works from quite an extended period of time. The articles included in the review were published in Polish and English.
Results: The review of articles concerning the treatment of anxiety disorders clearly suggests that propranolol is effective in reducing the frequency of panic attacks and the tendency for avoidance behavior in patients with agoraphobia. Other studies report on potential benefits in terms of early interventional prevention and treating posttraumatic stress disorder with propranolol. However, there is lack of randomized clinical trials concerning the therapeutic effect of other adrenolytic drugs in treating anxiety disorders. Early research works reported that (mainly lipophilic) beta blockers may have a depressogenic effect; however, the latest studies have not confirmed it.
The contemporary research on the therapeutic potential of beta blockers in treating anxiety disorders is insufficient. What seems to be most promising, however, are reports concerning the desirable effects of using adrenolytic drugs in treating posttraumatic stress disorder, which implicates the necessity of conducting further research verifying the validity of their application.
Grzegorz Józef Nowicki, Barbara Ślusarska, Ewa Rudnicka-Drożak, Anna Wiśniewska, Bernadeta Jędrzejkiewicz, Kamil Pielaszkiewicz and Aleksandra Sekut
Aim. Determination of health behaviors in the group of people performing medical and non-medical professions.
Material and methods. The research covered 598 individuals divided into two groups: those performing medical professions (group M, n = 305) and non-medical (group P; n = 293). Standardized tools were used: Health Behavior Inventory, Multidimensional Health Locus of Control Scale - version B, General Self-Efficacy Scale on risk factors and prevention of civilization diseases (own authorship). The controls were subjected to measurement of blood pressure as well as their height and body mass tests.
Results. In group M, the level of self-efficacy, the location of health control in terms of the influence of the others and the chance, age, incidence of cardiovascular diseases in the father, smoking and the level of mean systolic blood pressure explain 17.5% of the variability of health behavior. In group P, the level of self-efficacy, location of health control in terms of the influence of the others and the chance, monthly net income per a family member, the occurrence of neoplasms in siblings, smoking, average blood pressure and the level of knowledge about risk factors and prevention of civilization diseases explain 27.9% of the variance of the health behavior variable.
Conclusions. There is a diversification of selected determinants of health behaviors in the group of individuals performing medical and non-medical professions, with their stronger impact on non-medical professionals (17.5% vs. 27.9% of their variability).