Waste negative impact on the environment and man is becoming one of the most important problems in all industrial countries. Waste amount grows every year. Waste may cause a complex negative impact on the landscapes of territories, biosphere and human health. Therefore, the task of development of efficient waste management system is so important. Examples of waste negative impact are considered in the present paper. Methods and approaches of reduction of waste negative influence are analysed. Suggestions for improving the existing waste management system of Russia are made. Results of approbation of the proposed waste management system in Samara region of Russia are considered.