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Carmen Popa, Violeta Anghelina and Octavian Munteanu

Abstract

In this paper the deformation state of a circular and isotropic plate is analyzed, using as methods of comparison the analytical, the finite element and the experimental element methods. In the finite element method, the plate is analyzed by several programmes, as well as assembled with the respective container.

Open access

Caterina Grif, C Rădulescu, S Voidăzan, Carmen Popa and O Grama

Abstract

Introduction: The assessment of the Doppler velocimetric indices of the uterine, umbilical and middle cerebral artery helps in diagnosing and monitoring pregnancies with fetal growth disorder.

Material and method: Two groups were studied: the 1st group SGA (small for gestational age) including 22 fetuses whose birth weight was below the 10th percentile for gestational age and the 2nd group AGA (appropriate for gestational age) comprising 58 fetuses whose birth weight was between the 10th and 90th percentile. According to Doppler changes we could identify fetuses with intra uterine growth restriction (IUGR) and perform a comparative analysis of Doppler changes according to frequency and also assessed the predictive accuracy of some abnormal velocimetric indices for diagnosing SGA.

Results: In the SGA group we found 8 fetuses with IUGR (36.3%), based on the fetal brain-sparing phenomenon indicated by Doppler changes. In the AGA group Doppler changes were observed in only 1 pregnancy (1.7%). The frequency of Doppler changes was significantly higher in the SGA group. The highest predictive accuracy for SGA was found for a cerebroplacental ratio (CPR) below 1.08 (88.89% PPV; 80.28% NPV; 36.36% Se and 98.28% Sp) with p < 0.0001.

Conclusions: Many cases of IUGR occur in pregnancies without evident risk factors as shown in this study. The most effective parameter for diagnosing SGA was found to be the CPR below 1.08.

Open access

Radu Iatan, Pavel Florescu, Carmen Popa and Gheorghiţa Tomescu

Abstract

Starting of the characteristic expressions of some breaking polynomial criteria, known and used in practice, it is highlighted how to assess the safety coefficients used in some practical cases. It is obvious that the decision belongs to the user given the experience in the adequate technical domain. In this regard it must not neglect the fact in that the breakage is produced most often in unpredictable moments, conditioned by multiple factors, dependent on material, on manufacturing technologies of finished products, respective the operating conditions.

Open access

Roxana Spulber, Carmen Chifiriuc, Mădălina Fleancu, Ovidiu Popa and Narcisa Băbeanu

Abstract

In a nanobiotechnology world with many applications in biomedicine, a novel combination of inorganic-organic materials is needed to prove a novel functionality. Natural compounds from bee pollen extract coated on magnetite nanoparticles could open up a new way in apitherapy field. Iron oxide nanoparticles have proved special requirements for biological applications like superparamagnetic properties, high biocompatibility and nontoxic material. Magnetite nanoparticles functionalized with natural bioactive substances extracted from bee pollen have been characterised and investigated for antimicrobial activity. Previous findings demonstrate that magnetite nanoparticles (MNPs) and pollen ethanolic extracts (PEE) exhibited antimicrobial activity against a large antimicrobial spectrum, including Grampositive, Gram-negative and antifungal microorganisms.

Open access

Vesa Cosmin Mihai, Zaha Carmen Dana, Popa Loredana, Cismaș-Pruteanu Petrișor, Moisi Mădălina, Popescu Mircea, Florica Mekereș, Daina Lucia, Maghiar Adrian and Popa Amorin

Abstract

Patients recently diagnosed with diabetes mellitus need to go to a complex evaluation regarding not only glycaemia and HbA1C, but also blood pressure values, lipid metabolism, kidney function, medical history and lifestyle choices. Cardiovascular risk assessment can reveal which patients fall into moderate and high categories of risk, where regular follow-up and intensive therapy addressing all the risk factors must be strictly performed. We selected a group made of 385 diabetes mellitus type II patients, a representative for the whole population of newly diagnosed diabetic patients from our county in 2017. We determined their anthropometric indicators, their biochemical parameters, their lifestyle choices and we assessed their coronary heart disease risk at 10 years using UKPDS risk engine.

Open access

Vesa Cosmin Mihai, Daina Lucia Georgeta, Popa Loredana, Moisi Mădălina, Zaha Carmen Dana and Popa Amorin Remus

Abstract

Diabetes incidence in Bihor County in 2016 was 0.55% or 558/100.000 and in 2017 was 0.43% or 437/100.000. The prevalence of diabetes was 5.24% in 2016 and 5.48% in 2017. Age adjusted prevalence was 7.20% in 2016 and 7.66% in 2017, in the 20-79 age group. This prevalence is lower than the national prevalence from PREDATORR study of 11.6%. Data from diabetes registers underestimate diabetes prevalence. As a consequence it is mandatory to effectuate a screening of diabetes mellitus in Bihor County.

Open access

Cristian Jinca, Carmen Angela Maria Petrescu, Estera Boeriu, Andrada Oprisoni, Loredana Balint-Gib, Mihaela Baica, Cristina Popa, Nicoleta Andreescu, Margit Serban, Emilia Ursu and Smaranda Arghirescu

Abstract

Introduction. The unsatisfactory results of the survival in patients with acute lymphoblastic leukemia (ALL) until 2000 in our center have led us to improve the approach of diagnosis and therapy. Since 2003 in all patients the following have been performed: flow cytometry, conventional genetic diagnosis, FISH (fluorescent in situ hybridization), and molecular biology. Objectives. Our aims were to identify solutions to increase patients’ survival. Patients and method. It is a single-center, retrospective study of 136 patients with ALL treated at 3rd Pediatric Clinic of Timisoara, over a period of 10 years (2003-2012), where survival was assessed. Results. Morphologically, 86% of the patients were L1 type, 13% L2 type and 1% L3 type. Flow citometry revealed that 68% were ALL with B precursors, and 19% with T immunophenotype. Acute leukemia with mixed phenotype (biphenotypic) was identified in 2.3% of patients and 10.7% of the forms were acute leukemia with myeloid markers. In 27.7% of patients, mutations were detected by the RT-PCR method, the most commonly identified was TEL-AML1 (ETV6- RUNX1) accounting for 12.7% of the cases. Relapse-free survival at 5 years for the entire group was 59%, and for the group treated between 2008 and 2012 it was 72%. Conclusion. Our analysis confirms the decisive value of laboratory investigations for the prognosis and improvement of supportive therapy.