The need to undertake research work on the commercialization of results from scientific research and development projects emerged from the Author’s professional experience as well as the incomprehensive literature on the role of Polish research institutes in the process of technology transfer and commercialization of innovative solutions, in particular in the case of mining machinery and equipment. From the available literature, the commercialization of research results and technology transfer are analyzed from the perspectives of academia and entrepreneurs, but there is no analysis of this challenge from the perspective of the research institutes which create the majority of innovative solutions implemented in Poland. The research results presented in this article identify and highlight not only the main factors which facilitate knowledge transfer in the widest sense, but also the barriers which should be overcome. An integrated commercialization model of research results, developed by the Author, is described in the article. Some examples of other models, used to assess innovative technology transfer processes, i.e. Transfer model of the Cracow University of Technology, Jolly’s model, United model (science + market), Trzmielak’s linear – subsequent model, Network – interactive model and IpOp model, are also presented. Special attention is paid to the process of generating innovative ideas and to the area of efficient project management. Based on the integrated model, practical management recommendations for the successful commercialization of innovative solutions are given. It is highlighted that the integrated model can be treated as a diagnostic tool, enabling an efficient assessment of the transfer of research results and commercialization of innovative solutions.