In the paper presented are the results of calculations using authors own model to predict heat transfer coefficient during flow boiling of carbon dioxide. The experimental data from various researches were collected. Calculations were conducted for a full range of quality variation and a wide range of mass velocity. The aim of the study was to test the sensitivity of the in-house model. The results show the importance of taking into account the surface tension as the parameter exhibiting its importance in case of the flow in minichannels as well as the influence of reduced pressure. The calculations were accomplished to test the sensitivity of the heat transfer model with respect to selection of the appropriate two-phase flow multiplier, which is one of the elements of the heat transfer model. For that purpose correlations due to Müller-Steinhagen and Heck as well as the one due to Friedel were considered. Obtained results show a good consistency with experimental results, however the selection of two-phase flow multiplier does not significantly influence the consistency of calculations.