Abdominal Compartment Syndrome as an Independent Mortality Predictor Factor During Acute Pancreatitis
Aim: The aim was to study the role of abdominal compartment syndrome and intra-abdominal hypertension (IAH) as indipendent predictor factors on outcome and mortality in patients during early phase of acute pancreatitis (AP).
Material and Methods: According the IAP 102 patients with medically treated AP were divided: in the first group (N = 32 patients) the IAP was over 12 mmHg, in second group (N = 27 patients) the IAP was over 20 mmHg (ACS), and the third group (N = 43 patients) with normal pressure. There were recorded APACHE 2 score in admission, the incidence of multiorganic dysfunction syndrome and mortality.
Results: No statistical significance is observed between three groups regarding age, gender, APACHE II score, Ranson score, CTSI. Kruskal-Wallis test resulted positive for all variables suggesting a statistically significant difference between groups. The pairwise test for comparison of subgroups according to Conover, yielded a statistically significant difference of ACS (p<0.05). ACS group resulted with more early deaths (13 patients) and total deaths (15 patients).
Conlusion: The abdominal compartment syndrome and increased intrabdominal pressure occurred during the early fase of AP may be predictors of increased MODS and mortality.