Power is seductive, and fantasies of power affect both men and women, who are sometimes willing to do anything in order to achieve or retain it. The paper looks at how such a modern transmediation as manga renders powerful femininity in two of Shakespeare’s great tragedies, namely Hamlet and Macbeth. The paper aims to discuss the ways in which the emotive behaviour of both female protagonists eventually makes them inappropriate for the power roles they assume as wives, queens and mothers.
This paper aims to revisit three adaptations of Red Riding Hood fairy tales and explore some of the wolf’s reincarnations in order to see how realities change in time. It has generally been observed in the literature that in pop culture Red has undergone quite dramatic changes from the little ingénue to the mature seductress. But what has happened to the bad wolf? How is he imagined by the 21st century pop culture? How do his agency and power change? What (new) message does he convey? To answer these questions, I shall look at three fairly recent advertisements that adapt the classic Little Red story for the screen: “Red Bull” energizer (February 2010), “Chanel no. 5” (featuring actress Estella Warren, late 1990s, 2007) and “B.U. Heartbeat” (featuring Tyson Kuteyi, 2008) perfumes. I will explore not only how such commercials reframe the dominant Western cultural pattern, but if they also undo the lessons both men and women have so far been forced to learn.
It is no secret that, over the past three decades, Romanian migrants have contributed to an ambivalent image of Romania and that cultural stereotypes have heavily influenced the negative portrayal of Romanians in European media, particularly so in the case of British newspapers (cf. Mădroane 2014). Among the people who have fought against such stereotypes is the Prince of Wales, who has endeavoured to promote a thoroughly positive image of Transylvania (and, by extension, of Romania) with its natural beauties, resources and traditions. What this paper aims to do is to explore this aspect as well as its effects in Romanian newspapers over a period of approximately eight years (2011-2018).
In Romania, Shakespeare played an important role in the construction of Romania’s cultural identity and in the reshaping of political awareness during the communist dictatorship. In recent years, the Bard’s work has been translated into a contemporary, accessible Romanian language, with theatrical or musical adaptations targeted at a public whose tastes are shaped by popular culture. The authors discuss, from this perspective, two recent adaptations: The Taming of the Shrew (2005), acclimatized to contemporary Romanian realities (names, locations and folk music), and Romeo and Juliet (2009) that relocates the tragedy in the musical genre. The choice of two musical genres popular with the most widely spread segments of the public - the conservative, but less educated middle-aged group of non-theatre-goers and the youth - indicates an attempt, still new for the Romanian cultural market, to accommodate Shakespeare to the interests of two different communities of consumers, so far absent from this country’s high culture circuit.
Introduction: Myxofibrosarcoma is a rare subtype of soft tissue sarcoma with a locally infiltrative behavior and ability to determine distant metastases.
Materials and methods: We presented two myxofibrosarcoma cases who benefited from segmental or radical resection.
Management and outcome: In the case of the 80-year-old woman, with grade 3 myxofibrosarcoma, we practiced radical surgery with scapulohumeral disarticulation followed by adjuvant radiotherapy.
The therapeutic option for the 77-year-old man with grade 2 myxofibrosarcoma was segmental resection followed by adjuvant radiotherapy. After three months, the patient was in a good clinical condition with no sign of local recurrence, but with the presence of pulmonary metastases for the patient who benefited of segmental resection.
Discussion: The radical resection had better short-term results, with no local or distant metastases at three months after surgery, although the tumor had a higher grade (G3), compared to segmental resection practiced for a lower grade tumor (G2), in which case the patient developed pulmonary metastasis at three months follow up.
Conclusion: Myxofibrosarcoma represents a challenging situation regarding the management due to its unpredictive clinical course. Our cases raised the following question: should we consider treating it more aggressively in order to obtain good local control and reduce the risk of metastasis?
Acute coronary syndromes exhibit rapid and variable ischemic dynamics, with consecutive electrocardiographic changes, sometimes in the absence of angina.
We report the case of a 50 year-old man, admitted for suspected angor de novo, asymptomatic upon admission, and with a normal electrocardiogram. After a few hours, the repeated electrocardiogram displays biphasic T waves in V2–V4, in the absence of symptoms, and then marked ST elevation in the same territory, without chest pain. The patient is transferred with a STEMI diagnosis, and the coronary angiography documents a critical sub-occlusive stenosis in the proximal segment of the left anterior descending artery (LAD), for which a drug-eluting stent is inserted, with a favourable evolution.
Wellens syndrome is defined by characteristic electrocardiographic changes of T waves in leads V2–V4, occurring in the context of unstable angina, usually without pain. They express a critical stenosis in the proximal LAD artery. Recognition of the Wellens syndrome is crucial, as these “pre-infarction” changes tend to evolve, sometimes rapidly, to an extensive anterior myocardial infarction. The rapid and unpredictable ischemic electrocardiographic changes make this case remarkable, as they occur in an asymptomatic patient with unstable angina (angor de novo), thus underlining the need for careful supervision in such patients.
This paper discusses notions of physical violence, domestic violence, and sexual assault and the ways in which these were socially and legally perceived in early modern Europe. Special attention will be paid to a number of Shakespearean plays, such as Titus Andronicus and Edward III, but also to the narrative poem The Rape of Lucrece (whose motifs were later adopted in Cymbeline), where the consumption of the female body as a work of art is combined with verbal and physical abuse.
A rapid, sensitive, high-throughput liquid chromatography coupled with tandem mass spectrometry method for the quantification of rivaroxaban from human plasma has been developed and validated. For the analytical separation a Zorbax SB-C18 column with isocratic flow of mobile phase composed of 0.2% formic acid in water and acetonitril (65:35, V/V) with a flow rate of 1 mL/min at a temperature of 45ºC was used. Detection of rivaroxaban was performed using positive electrospray ionization and MS/MS mode (sum of m/z 231.1; 289.2 and 318.2 from m/z 436.3). Plasma samples were prepared using single-step protein precipitation with methanol. Method validation was performed with regards to selectivity, linearity (r >0.9927), within-run and between-run precision (CV< 13.1 %) and accuracy (bias< 9.4 %) over a concentration range of 24.00 - 960.00 ng/mL plasma. Recovery was between 96.5 - 108.5% and the lower limit of quantification of rivaroxaban was 24.00 ng/mL. The developed method is simple, rapid, and selective, requires small plasma sample volumes, and was successfully applied for therapeutic drug monitoring of rivaroxaban in treated patients.