Background and aims: To assess the levels of total testosterone in the metabolic syndrome patients.
Material and Methods: We included ninety-six patients in our study, forty-nine with metabolic syndrome according to the definition of International Diabetes Federation (IDF) and forty-seven as control. Anthropometric measurements were registered and blood samples were taken after an overnight fast.
Results: The mean values of different parameters showed significant differences between both groups. The total testosterone mean value was (338,97±91,2 ng/ml) substantially lower as compared to patients with metabolic syndrome to control group.
Conclusion: There is an inverse relationship between total testosterone and metabolic syndrome. Low total testosterone can be a predictor of rising incidence of metabolic syndrome.
Metabolic syndrome is a group of conditions that increases the risk of developing diabetes and cardiovascular diseases. The most important pathogenic factors for metabolic syndrome are insulin resistance and obesity. The clinical presentation of this syndrome results from its influence on glucose and fat metabolism. Testosterone deficiency has a prevalence of up to 50% in men with metabolic syndrome and type 2 diabetes mellitus. A low level of testosterone is a factor for cardiovascular diseases and predictor of metabolic syndrome and, on the other hand, the components of metabolic syndrome can lead to low testosterone. This article reveals the bidirectional link between low testosterone level or hypogonadism and metabolic syndrome.