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  • Author: Aleksandar Đorđević x
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Summary

Background/Aim: Implant treatment expands extensively the possibilities of prosthetic treatment, which provide benefits, bigger comfort as well as general improvement of the patient’s life quality. In cases with no possibility of implantation, it is possible to improve conditions by using modern methods for bone tissue repair. One of factors important for the long-term success is proper oral hygiene, as well as raising awareness of its importance to patients. The aim of the paper is to present a patient rehabilitated with multiple implants and followed-up for a five-year period, and to point out the importance of raising patient’s awareness and motivation in order to preserve the results of the treatment.

Case Report: A 31-year-old patient was admitted to the oral surgery clinic for rehabilitation of a poor oral health status. After taking history, clinical examination and additional analysis, the following treatment plan was suggested: to remove impacted upper canines and to put an implant supported by fixed prosthesis in the upper jaw, to make two implants supported by bridges laterally and one dental supported by bridge in the inter-canine sector in the lower jaw. The treatment was carried out in several stages that involved extraction of residual roots and impacted teeth, augmentation of bone defects with bone substitutes and bio-absorbable membranes, placing implant, and prosthetic rehabilitation. By verbal communication with the patient, we pointed out the importance of proper oral hygiene and regular check-ups. The five year follow-up showed the absence of factors that could adversely affect the success of the treatment, and the patient was still highly motivated to maintain proper oral hygiene.

Conclusions: It is possible to achieve predictable results in complex cases by using a multiphase prosthetic treatment supported by implants. Concerning a long-term success, motivation, proper information and patient’s willingness to cooperate play an important role.

Abstract

This is a preliminary study of the depth distribution of 137Cs radionuclides in cultivated anthrosol soil of a 15-year old peach tree plantation at the experimental field “Radmilovac” near Belgrade. Before planting, the soil was ploughed at the depth of 1 m. The soil had not been annually ploughed, irrigated and treated with mineral fertilizers for three years before sampling. Activity concentration for 137Cs ranged from 1.8 Bq kg-1 to 35 Bq kg-1. Along the soil depth it varied highly, reaching as high a total variation coefficient as 83 %. Radiocaesium distribution patterns depended on the extent of soil mixing in the plough layer, as it was mechanically transferred from the surface to the lower soil layers during cultivation. 137Cs was associated with humus content and fixation to clay fractions in the soil. Our results single out soil’s hygroscopic water as a valuable parameter for 137Cs behaviour that could be used commonly if the measurement is standardised.

Abstract

Melanoma rarely develops in the genital area. It is responsible for 5% of all vulvar malignancies. Postmenopausal women are usually more affected and the main differential diagnosis is vulvar melanosis and vulvar nevi. There are limited numbers of studies on dermoscopic features of mucosal melanoma, particularly early-stage lesions. Dermoscopic criteria have been described for the diagnosis of vulvar melanosis, and observational studies have been conducted to define the dermoscopic features of nevi and melanoma on the vulva. We are presenting the case of a 69-year old female with suspected recurrence of vulvar melanoma who previously had surgical removal of mucosal lentiginous melanoma on the left labia minor in June 2017. Five months after the primary melanoma surgery, the patient noticed de novo pigmentation at the left and right labia minor and urethral opening. On clinical examination, irregular light-brown pigmentation with ill-defined borders was evident on the labia minora of the vulva and around the external urethral orifice. On dermoscopy, irregular pigmented network, with white scar-like and structureless pinkish areas was evident. Incisional biopsy of the vulvar mucosa revealed melanoma in situ, confirming the local recurrence. CT scans of the head, thorax, abdomen and pelvis and gynaecological examination revealed no secondary deposits. Ultrasound of the regional inguinal lymph nodes revealed enlarged suspected pathologic involvement of the lymph nodes in both inguinal regions. Lymph node fine needle aspiration of lymph nodes in the left and right inguinal area revealed pleomorphic infiltrate of lymphoid cells with hemosiderin or melanoma pigment in the cytoplasm. Cystoscopic findings were within normal range. Interdisciplinary tumour board indicated wide excision of melanoma with margins of 1 cm and resection of the urethra, as well as biopsy of the enlarged left inguinal lymph node. Histopathological analysis of the resected mucosa revealed lentiginous spread of melanocytes showing moderate atypia, with focal pagetoid spread, without mitoses and ulceration and without invasion of lamina propria. The resection margins were tumour-free. Non-specific lymphadenitis was diagnosed on lymph node histopathological analysis. The patient was regularly monitored by a dermatologist and urologist, and had no recurrence. The accurate and prompt diagnosis is essential in the case of the vulvar melanoma which has unfavourable and unpredictable prognosis, with a tendency of local recurrences and regional and distant metastases in the case of invasive melanoma. In order not to miss early mucosal melanoma, dermatologists and gynaecologists should not avoid biopsy of lesions that demonstrate any clinical or dermoscopic feature of atypical melanocytic lesion, especially in case of the development of irregular pigmentation that expands and changes over time, the appearance of a solitary amelanotic papule or nodule requires excision or, in case of large diameter lesions, incision biopsies. Larger studies are needed to define more rigorously clinical and dermoscopic criteria that accurately distinguish early mucosal melanomas from benign skin lesions.

Abstract

Hotels offer different types of services which have different impacts on the users’ satisfaction and have an influence in various extents on decision making, when it comes to the selection of hotels. As a part of research, empirical analysis based on the importance of different services which hotels provide, was conducted. The idea of research is to determine the importance of different types of services for users. The survey was conducted on a sample of 850 respondents in Serbia. The study used AHP methodology which is used in the decisionmaking process analysis and is suitable for studies defining the rank of relevance of individual elements. The obtained results presented in the study provide information such as, what services offered by hotels have the greatest importance for users. Based on the obtained results in empirical research, and by applying cluster analysis, two different segments of hotel guests are identified based on the preferred services. Segments are statistically different and can represent various targets in the hotel business policy.

Abstract

The focus of our research was to evaluate different apples cultivars in terms of their biological properties and bioactive compounds content, and determine the levels of their resistance (or susceptibility) to fire blight. The properties of 10 scab-resistant apple cultivars were examined on the Žiča monastery estate (West Serbia) during the period from 2011 to 2015. The biological and chemical properties such as firmness, maturity stage, total soluble solids, total acids, total and reducing sugars, ascorbic acid content and surface blush of apple fruits were monitored. Various phenolic compounds in the tested samples were tentatively identified by LC-MS analyses. A study of generative properties included: number of flower buds, fruit mass and width, crop load, yield efficiency and yield. During the period of blooming and intensive shoot growth, artificial inoculations were carried out. For each cultivar, a fire blight score was determined by dividing the average length of necrotic tissue by the average total shoot length. In the study period, the cultivars ‘GoldRush’ (41.1 t ha−1) and ‘Florina’ (35.9 t ha−1) produced the highest yields, and the cultivars ‘Discovery’ (19.0 t ha−1) and Selection 25/63 (15.1 t ha−1) the lowest. The cultivar ‘William’s Pride’ produced the largest fruits, with an average fruit mass of 206.8 g. The earliest harvest period was recorded for the cultivar ‘Discovery’ (end of July), and the latest for the cultivar ‘GoldRush’ (beginning of October). The cultivar ‘Enterprise’ had the highest value of total phenols (432.2 mg 100 g −1 FW), while the cultivar ‘Topaz’ had the highest value of total flavanols (145.2 mg 100 g−1 FW). The highest degree of susceptibility to fire blight was found in Selection 25/63, and the greatest resistance was manifested by the cultivar ‘GoldRush’. In the five-year study period, the cultivars ‘GoldRush’, ‘Rewena’ and ‘Enterprise’ exhibited better bio-chemical properties and higher levels of resistance to fire blight than the remaining cultivars.